A5051528562- Cancer Genomics and Diagnostics
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pancreatic and Hepatic Oncology Research
- Parvovirus B19 Infection Studies
- Cancer Mechanisms and Therapy
- Breast Cancer Treatment Studies
- Genetic factors in colorectal cancer
- Burkholderia infections and melioidosis
- Molecular Biology Techniques and Applications
- High Altitude and Hypoxia
- Dermatological and COVID-19 studies
- Salivary Gland Tumors Diagnosis and Treatment
- Cytomegalovirus and herpesvirus research
- Animal Virus Infections Studies
- Hemostasis and retained surgical items
- Epigenetics and DNA Methylation
- Heme Oxygenase-1 and Carbon Monoxide
- Hemophilia Treatment and Research
- Pneumocystis jirovecii pneumonia detection and treatment
- Phytochemistry and biological activities of Ficus species
- Complementary and Alternative Medicine Studies
- Cancer, Hypoxia, and Metabolism
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Diphtheria, Corynebacterium, and Tetanus
- Otolaryngology and Infectious Diseases
Sri Ramachandra Institute of Higher Education and Research
2018-2025
Dr. Ram Manohar Lohia Institute of Medical Sciences
2016-2024
King George's Medical University
2024
Institute of Genomics and Integrative Biology
2022-2024
Academy of Scientific and Innovative Research
2022-2024
National Center for Disease Control
2022
Tata Memorial Hospital
2019
All India Institute of Medical Sciences
2016
This study aimed to identify B-cell epitope candidates using multiple identification software and in silico analysis of the modeled B19 V protein against specific antibodies molecular docking dynamics simulation. Materials Methods: Full-length amino acid sequences VP1 were retrieved from NCBI. A consensus sequence was generated CLC viewer. Linear B cell epitopes identified Bepipred 2.0, ABCpred, LBTope. The linear synthesized validated V-specific antibodies. 3D model ITASSER server....
Gallbladder carcinoma, uncommon in most of the world, is frequent South East Asia. It presents advanced stages with limited therapeutic options. We investigated targetable predictive and prognostic Markers 268 cases including 233 primary site lesions 35 metastatic gallbladder carcinoma.EGFR, VEGF, HER2/Neu p53 were assessed using immunohistochemistry. was validated a subset by fluorescent situ hybridization (FISH) tissue microarray (TMA). Broader spectrum gene variation screened NGS...
Biopsy of palpable breast masses can be performed manually by palpation guidance or under imaging guidance. Based on retrospective studies, image guided biopsy is considered more accurate than biopsy; however, these techniques have not been compared prospectively. We conducted this prospective study to verify the superiority and determine size beneficial effect over biopsy.Over a period 18 months, 36 patients each with were randomized into arms. Ultrasound was used for in 33 mammographic...
Background: Development of inhibitors to transfused factor VIII in patients with hemophilia A continues be a challenge for professionals involved care. The majority India receive ‘on-demand’ rather than prophylactic therapy. present study was done assess the prevalence (PWHA) receiving therapy North Indian population and clinicopathological parameters influencing development inhibitors. Methods: group comprised 300 PWHA. Detailed clinical parameters, treatment history, bleeding profile...
The utility of cell-free (cf) DNA has extended as a surrogate or clinical biomarker for various diseases. However, more profound and expanded understanding the diverse cfDNA population its correlation with physiological phenotypes environmental factors is imperative using full potential. high-altitude (HA; altitude > 2,500 m above sea level) environment characterized by hypobaric hypoxia offers an observational case-control design to study differential profile in patients pulmonary edema...
A core component of every blood program is the supply safe and products. The elevated risk transmission through these products due to parvovirus B19 (B19V) resistance virus inactivation procedures. Our study aimed screen asymptomatic donors for B19V at a tertiary care hospital in Chennai, Tamil Nadu, between September 2020 June 2021. Sera from 106 healthy who tested negative Human immunodeficiency (HIV), Hepatitis B surface antigen (HBsAg), C (HCV), syphilis, malaria were anti-B19V IgM IgG...
Abstract The dramatic changes in physiology at high altitude (HA) as a result of the characteristic hypobaric hypoxia condition can modify innate and adaptive defense mechanisms body. As consequence, few sojourners visiting HA with mild or asymptomatic infection may have an enhanced susceptibility to high-altitude pulmonary edema (HAPE), acute but severe sickness. It develops upon rapid ascent altitudes above 2500 m, otherwise healthy individuals. Though HAPE has been studied extensively,...
Burkholderia is a genus consisting of several species including the pseudomallei group, cepacia complex and other phytopathogens. gram-negative bacillus with protean presentation that can be acquired from various sources, water, soil, plant surfaces, hospital environments. The organism on Gram staining seen as rod culture, colonies are non-lactose fermenting. As it mimic diseases, frequently misdiagnosed there lack awareness about clinical spectrum disease diagnosis. This study aims to...
first_page Download PDF settings Order Article Reprints Font Type: Arial Georgia Verdana Size: Aa Line Spacing: Column Width: Background: Open AccessAbstract The Development and Standardization of a U-Bent LSPR Fiber Optic Biosensor to Screen for Parvovirus B19 IgM † by Reuben Kuruvilla ThomasReuben Thomas SciProfiles Scilit Preprints.org Google Scholar 1,*, Ratan Kumar ChaudharyRatan Chaudhary 2, Vikraman AruldossVikraman Aruldoss Swati KumariSwati Kumari 1, Padma SrikanthPadma Srikanth...
Introduction:There are, at present, no biomarkers to predict prognosis of Gallbladder cancer.We conducted a prospective exploratory study evaluate the role serum CA 19-9 and 242 as prognostic markers.Material Methods: We enrolled consecutive patients for this were estimated from venous samples.Association these markers with clinical variables median overall survival (OS) difference between who has raised versus normal levels was determined.Results: Sixty-two study.Forty-four (71%) had...
Context: Circulating free DNA (cfDNA) analysis has emerged as novel noninvasive diagnostic biomarker in several solid tumors. Raised levels have been reported malignancies and may correlate with clinicopathological treatment response. The current study was designed to assess the diagnostics of cfDNA different tumor types correlating (T), nodes (N), metastases (M) stage. Design: Serum samples were collected from naïve cases histologically diagnosed tumors including 23 brain tumors, 48...
The incidence of extraintestinal infection caused by Salmonella spp has been increased during the past decade. Here we report a case parotid abscess enterica subspecies serotype Typhi ( S . Typhi) in an individual without any significant abnormality gland. A 68-year-old man presented to surgical department with high-grade intermittent fever associated painful swelling over right side face, extending into neck. An ultrasound neck revealed was isolated from pus drained patient treated...
Burkholderia is a genus consisting of several species including the pseudomallei group, cepacia complex and other phytopathogens. Gram-negative bacillus with protean presentation which can be acquired from water or soil sources. This causes infectious disease public health importance. It considered as potential biological weapon it resistant to multiple classes antibiotics cause high mortality rate. The organism on Gram staining seen negative rod characteristic safety pin appearance culture,...