A5051536473- Cervical Cancer and HPV Research
- Lymphoma Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- Hemophilia Treatment and Research
- Platelet Disorders and Treatments
- Hematological disorders and diagnostics
- AI in cancer detection
- Sarcoma Diagnosis and Treatment
- Long-Term Effects of COVID-19
- Acute Lymphoblastic Leukemia research
- Fungal Infections and Studies
- Sepsis Diagnosis and Treatment
- Cancer Genomics and Diagnostics
- Cutaneous lymphoproliferative disorders research
- Oral and Maxillofacial Pathology
- Pleural and Pulmonary Diseases
- Acute Myeloid Leukemia Research
- Viral-associated cancers and disorders
- Bone Tumor Diagnosis and Treatments
- Cancer Cells and Metastasis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Blood Coagulation and Thrombosis Mechanisms
- T-cell and Retrovirus Studies
- Pancreatic and Hepatic Oncology Research
- Carcinogens and Genotoxicity Assessment
Dr. Ram Manohar Lohia Institute of Medical Sciences
2014-2024
Sanjay Gandhi Post Graduate Institute of Medical Sciences
2011-2021
Purpose: Liquid biopsy has entered the arena of cancer diagnostics in past decade and detection circulating tumor cells (CTC) is one diagnostic component. CTCs gallbladder (GBC) have hitherto not been comprehensively analysed. Methods Results: The current study focused on role 27 cases treatment-naive GBC 6 normal controls as well cholecystitis. An EasySep kit featuring negative immunomagnetic bead separation flow cytometric EpCAM positive CD45 revealed 25 cases. At a cut-off point ≥1, CTC...
Background: Development of inhibitors to transfused factor VIII in patients with hemophilia A continues be a challenge for professionals involved care. The majority India receive ‘on-demand’ rather than prophylactic therapy. present study was done assess the prevalence (PWHA) receiving therapy North Indian population and clinicopathological parameters influencing development inhibitors. Methods: group comprised 300 PWHA. Detailed clinical parameters, treatment history, bleeding profile...
We measured the expression of serum procalcitonin (PCT), quantitative C-reactive protein (QCRP), neutrophil CD64 (nCD64) and monocytic HLA-DR (mHLA-DR) sequentially in patients admitted to intensive care unit (ICU) correlated these biomarkers predict development sepsis its outcome.Consenting adult more than 18 years age, who developed during an observation period 20 days with a sequential organ failure assessment score (SOFA) ≥ 2 or those already had at admission ICU were included. SOFA...
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) modulates antiviral immunity via T cells, but whether these cells are active or abundant in coronavirus disease 2019 (COVID-19) patients is unknown. The present study aimed to investigate the temporal shifting T-cell population and their subsets, T-Helper (Th) cell (CD4) T-Cytotoxic (Tc) (CD8) COVID-19 patients.Thirty confirmed (nasal swab reverse transcription-polymerase chain reaction (RT-PCR) confirmed) were enrolled. On basis...
Background: DNA ploidy analysis of cervical intraepithelial neoplasia (CIN) and invasive cancer samples by flow cytometry (FCM) has been established as an aid to prognostic assessment. Liquid based cytology (LBC) increases diagnostic specificity using ancillary techniques that provide information beyond morphology. The present study was undertaken assess in LBC adjunct for early detection pre-cancer cancer. Methods: assessment performed on 50 cases 31 controls. Cell pellets were obtained...
Abstract Background Mammography is the primary imaging modality for diagnosing breast cancer in women more than 40 years of age. Digital tomosynthesis (DBT), when supplemented with digital mammography (DM), useful increasing sensitivity and improving BIRADS characterization by removing overlapping effect. Ultrasonography (US), combined above combination, further increases diagnostic confidence. Since most research regarding has been screening settings, we wanted to quantify its role...
Cystic liver lesions in an adult may occur for a variety of reasons, most which are benign nature. Infiltrating the parenchyma pose clinical challenge diagnosis and management. In case presented herein, cystic lesion adjacent to gall bladder involving had be differentiated from carcinoma, is quite common India. Parasitic infestation extremely rare presentation significant its This highlights infrequent challenges approach subsequent
ABSTRACT A 71‐year‐old man presented with erythroderma and multiple nodular skin lesions over the face, scalp, upper limbs trunk. The facial was thickened, producing rare ‘leonine facies’ appearance. Investigations revealed presence of atypical lymphoid cells in peripheral blood, bone marrow skin. blood were positive for helper T‐cell antigens (CD4, CD2, CD5 CD7) on immunophenotyping by flow cytometry. histopathology showed dermal infiltration small lymphocytes epidermotropism. These...
Although several peripheral blood abnormalities have been reported in COVID 19,Leukoerythroblastosis is an unusual finding. We report 33 COVID19 cases presenting with leukoerythroblastosis. intend to describe its incidence this novel viral infection and correlate it the clinical outcome.It a Prospective study done at Level 3 19 hospital of LUCKNOW, INDIA. Hematologic test records day 1 admission admitted from 20th August 2020 30th September were reviewed. Peripheral smear examination was...
Non-Hodgkin's lymphoma are neoplasms derived from T cells and B their precursors in the lymphoid system with higher susceptibility involvement of extra-nodal sites. Predominant ureteric is an unusual presentation. We present a case diffuse large B-cell secondary ureter who had symptoms urinary tract infection absence positive urine culture, non-responsive to broad spectrum antibiotics masquerading pyogenic leading pyelonephritis ureteritis. Radiological examination revealed mass like soft...
Solitary plasmacytoma of bone are a spectrum plasma cell disorder which defined by presence clonal in the including skull. The occurrence true skull with large amyloid deposits young patient is rare presentation. We present case 25-year-old man 3-month history slowly growing mass occipital region associated headache. Neurological examination was within normal limits. Magnetic resonance imaging revealed extra-axial mass, inner table were partially destroyed tumour, but dura not involved....
We report the cytological findings of a sacro-coccygeal chordoma in 53 year male diagnosed preoperatively by guided fine needle aspiration cytology. The smears shows characteristic Physalliphorous cells metachromatic background myxoid material entrapping cords cuboidal cells. Differential diagnosis cytology include conventional and chondrosarcoma, liposarcoma, malignant fibrous histiocytoma, metastatic mucinous carcinoma myxo-papillary ependymoma. distinguishing features between these...