- Natural Antidiabetic Agents Studies
- Microplastics and Plastic Pollution
- Graphene and Nanomaterials Applications
- Plant biochemistry and biosynthesis
- biodegradable polymer synthesis and properties
- Silk-based biomaterials and applications
- Machine Learning in Bioinformatics
- Synthesis and biological activity
- Drug-Induced Hepatotoxicity and Protection
- Curcumin's Biomedical Applications
- Cardiac Ischemia and Reperfusion
- vaccines and immunoinformatics approaches
- Advanced Glycation End Products research
- Cholinesterase and Neurodegenerative Diseases
- Viral Infections and Immunology Research
- Phytochemicals and Antioxidant Activities
- Metabolomics and Mass Spectrometry Studies
- Cardiac Fibrosis and Remodeling
- Beetle Biology and Toxicology Studies
- Lipoproteins and Cardiovascular Health
- Fluoride Effects and Removal
- PARP inhibition in cancer therapy
- Sarcoma Diagnosis and Treatment
- Gout, Hyperuricemia, Uric Acid
- Microbial Fuel Cells and Bioremediation
Integral University
2015-2025
University of Waterloo
2011
Abstract: Silver nanoparticles (AgNps) have attracted maximal attention among all metal nanoparticles, and the study of their biological properties has gained impetus for further medical adoption. This evaluated cellular molecular mechanisms associated with action AgNps against an opportunistic pathogen, Candida albicans . Spherical, stable AgNp (average size 21.6 nm) prepared by a chemical reduction method showed minimum inhibitory concentration (required to inhibit growth 90% organisms) at...
Boerhaavia diffusa Linn. of family Nyctaginaceae is a known traditional medicinal plant and has been used in the treatment many free radical mediated diseases. Excessive formation radicals, either reactive oxygen species (ROS) or nitrogen (RNS) responsible for damaging various biomolecules like DNA, lipids proteins. The present investigation was initially carried out to explore possible link between antioxidant, oxidative DNA damage protective α-amylase inhibitory property B. root extract...
Abstract Background Curcumin, quercetin and rutin are flavonoids having strong antioxidant potential, individually used in treatment of numerous ailments. The safety assessment each them is already established but no toxicological has been done that would guarantee the safe use these three when as a polyherbal combination (PHC). aim this study to evaluate possible effect female Swiss albino mice. Methods In acute toxicity study, oral dose poly herbal was administered four groups stepwise...
The receptor of Advanced Glycation Endproducts (RAGE) and (AGE) have multiple functions in our body their restraint are being observed neurodegenerative memory impairment disorders. review different pathways allows an understanding the probable mechanism neurodegeneration involving RAGE AGE. Commonly we observe AGE accumulation neural cells tissues but extent increases with presence disorder. AGEs can also be seen morbid accumulation, pathological structures form amyloid clots, nervous...
The silkworm cocoon has been used in the treatment of various ailments different Asian countries. This research was designed to evaluate effect sericin on myocardial necrosis and hypertrophy isoproterenol-challenged rats. rats were administered with (500 1000 mg/kg, p.o.) for 28 days, followed by administration isoprenaline (85 s.c.) 29th 30th days. cardioprotective activity assessed physical, enzymatic, histopathological parameters along apoptotic marker expression. showed that...
Abstract Background Sericin is a widely used protein in the pharmaceutical industry derived from silkworm, Bombyx mori , and for treatment of various diseases pathological conditions. It main ingredient Unani preparation khameera abresham. The study was conducted to evaluate preclinical toxicity silk sericin mice. Methods In acute study, administered once orally different groups animals at doses 500, 1000, 2000 mg/kg. Animals were observed 14 days. sub-acute mice 4 weeks toxic group mg/kg,...
Abstract Cardiometabolic disorders (CMD) is a constellation of metabolic predisposing factors for atherosclerosis such as insulin resistance (IR) or diabetes mellitus (DM), systemic hypertension, central obesity, and dyslipidemia. diseases (CMDs) continue to be the leading cause mortality in both developed developing nations, accounting over 32% all fatalities globally each year. Furthermore, dyslipidemia, angina, arrhythmia, heart failure, myocardial infarction (MI), are major causes death,...
A bacterial strain Azohydromonas australica DSM 1124 has been chosen, which is accumulated intracellular polyβ-hydroxybutyrate particles, each method merit and demerit for employed in PHB extraction.Our study, we have selected chloroform-sodium hypochlorite method.It one of the methods extracting forms 1124.Polyhydroxybutyrate a biodegradable biocompatible thermoplastic with many interesting applications medicine, food packaging tissue engineering materials.That does not produce any toxins...