A5060619291- Sepsis Diagnosis and Treatment
- Metabolomics and Mass Spectrometry Studies
- Respiratory Support and Mechanisms
- Hemodynamic Monitoring and Therapy
- Nosocomial Infections in ICU
- Central Venous Catheters and Hemodialysis
- Intensive Care Unit Cognitive Disorders
- Pancreatitis Pathology and Treatment
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Cardiac Arrest and Resuscitation
- Renal function and acid-base balance
- Antifungal resistance and susceptibility
- Tracheal and airway disorders
- Antibiotic Use and Resistance
- Antibiotic Resistance in Bacteria
- Thermal Regulation in Medicine
- Diet and metabolism studies
- COVID-19 Clinical Research Studies
- Airway Management and Intubation Techniques
- Electrolyte and hormonal disorders
- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Vascular Procedures and Complications
- Abdominal Surgery and Complications
Sanjay Gandhi Post Graduate Institute of Medical Sciences
2016-2025
Creative Commons
2023
Society of General Internal Medicine
2023
Christie's
2020
University of Lucknow
2015-2020
Society of Critical Care Medicine
2018
Engineering Associates (United States)
2016
New York Proton Center
2016
Centre of Biomedical Research
2015
Dr. A.P.J. Abdul Kalam Technical University
2015
Aluminum phosphide (AlP) is a cheap, effective and commonly used pesticide. However, unfortunately, it now one of the most common causes poisoning among agricultural pesticides. It liberates lethal phosphine gas when comes in contact either with atmospheric moisture or hydrochloric acid stomach. The mechanism toxicity includes cellular hypoxia due to effect on mitochondria, inhibition cytochrome C oxidase formation highly reactive hydroxyl radicals. signs symptoms are nonspecific...
OBJECTIVE To report the International Nosocomial Infection Control Consortium surveillance data from 40 hospitals (20 cities) in India 2004–2013. METHODS Surveillance using US National Healthcare Safety Network’s criteria and definitions, methodology. RESULTS We collected 236,700 ICU patients for 970,713 bed-days Pooled device-associated healthcare-associated infection rates adult pediatric ICUs were 5.1 central line–associated bloodstream infections (CLABSIs)/1,000 line–days, 9.4 cases of...
An important risk factor for nosocomial infection in an intensive care unit (ICU) is prior colonization. This study was undertaken to determine the spectrum of bacterial colonization and predisposing factors patients being admitted ICU India, with special emphasis on extended-spectrum beta-lactamase (ESBL)- metallo-beta-lactamase (MBL)-producing Gram-negative bacteria. Nasal, oral rectal swab samples were collected processed isolation ESBL-producing bacteria MBL-producing Pseudomonas...
Acute respiratory distress syndrome (ARDS) is associated with high mortality rates, which are further exacerbated when accompanied by acute kidney injury (AKI). Presently, there a lack of comprehensive studies thoroughly elucidating the metabolic dysregulation in ARDS patients AKI leading to poor outcomes. We hypothesized that metabolomics can be potent tool highlight differences profile unraveling unidentified pathophysiological mechanisms and without AKI.
Despite advancements in ventilator technologies, lung supportive and rescue therapies, the outcome prognostication acute respiratory distress syndrome (ARDS) remains incremental ambiguous. Metabolomics is a potential insightful measure to diagnostic approaches practiced critical disease settings. In our study patients diagnosed with mild moderate/severe ARDS clinically governed by hypoxemic P/F ratio between 100–300 but indistinct molecular phenotype were discriminated employing nuclear...
Diaphragm ultrasound (DUS) is a well-established point of care modality for assessment dimensional and functional aspects the diaphragm. Amongst various measures, diaphragmatic thickening fraction (DTf) more comprehensive. However, there still uncertainty about its capability to predict weaning from mechanical ventilation (MV). The present prospective observational exploratory study assessed diaphragm at variable negative pressure triggers (NPTs) with US in ICU patients.Adult patients...
To evaluate the incidence, risk factors and associated mortality of central line-associated bloodstream infection (CLABSI) in an adult intensive care unit (ICU) India.This prospective observational study was conducted over a period 16 months at tertiary referral medical center.We this center.All patients with venous catheter (CVC) for >48 h admitted to ICU were enrolled.Patient characteristics included underlying disease, sequential organ failure assessment (SOFA), acute physiology chronic...
Limited studies are available on prevalence and severity of vitamin D deficiency in a critically ill population. To the best our knowledge, this first study its kind an Indian intensive care set-up.One hundred fifty-eight patients were prospectively enrolled for over 2 years. Demographic profile clinical characteristics noted. Blood sample serum 25 (OH) was collected admission (4 ml). Serum measured using radioimmunoassay kit. Vitamin labelled as insufficient (31-60 nmol/l), deficient (15-30...
Predisposing aetiologies in Acute Respiratory Distress Syndrome (ARDS), perpetuates to heterogeneous clinical course hampering therapeutic response. Therefore, physiological variables need be identified by stratifying ARDS subphenotypes and endotype, target heterogeneity. The present study is stimulated the fact that heterogeneity arises from diverse pathophysiological changes leading distinct endotypes characterized perturbed biological mechanism which can exploited terms of metabolic...
Background: Traumatic brain injury (TBI) is a major cause of mortality among young individuals, accounting for 65% deaths in road traffic accidents.Paroxysmal sympathetic hyperactivity (PSH) common syndrome associated with TBI.This study represents the first prospective investigation aimed at assessing impact gabapentin on TBI patients, focusing prevention secondary and edema while enhancing Glasgow Coma Scale (GCS). Materials methods:The was conducted from September 2019 to July 2021 after...
Nosocomial infection caused by Pseudomonas aeruginosa (P. aeruginosa) is very common, despite the application of various preventive measures in intensive care units (ICUs) leading to increased morbidity, mortality, prolonged hospital stay, and treatment cost.The aim present study identify source P. patients admitted tertiary ICU.From 200 selected randomly, appropriate clinical specimens from different sites were collected processed for isolation identification nosocomial pathogens....
Metabolomics is emerging as a significant approach to reflect the individual's response pathophysiological conditions. Nuclear magnetic resonance (NMR) spectroscopy has evolved tool identify metabolic dysregulations in critically ill patients afflicted with conditions like acute respiratory distress syndrome (ARDS), severe pancreatitis (SAP), kidney injury (AKI), and sepsis. The spectral data from serum sample of study control group are recorded using an 800 MHz NMR spectrometer processed...
This study aimed to examine the clinical characteristics, weaning pattern, and outcome of patients requiring prolonged mechanical ventilation in acute intensive care unit settings a resource-limited country.This was prospective single-center observational India, where all adult were followed for duration pattern survival at both discharge 12 months. The definition used that National Association Medical Direction Respiratory Care.During one-year period, 49 with mean age 49.7 years had...
IntroductIonSepsis is the manifestation of complex interactions between invading microorganisms and immune, inflammatory, coagulation responses host. [1]Coagulopathy in sepsis a risk factor for mortality.Conventional assays (CCAs) include prothrombin time/international normalized ratio (INR), activated partial thromboplastin time (aPTT), platelet count (PLT), fibrinogen.CCAs are routinely used to diagnose disorders also guide transfusion practices.However, CCAs have many limitations....
Background: A high incidence of errors occur while filling up death certificates in hospitals. The purpose this study was to analyze the impact an educational intervention on certification intensive care unit (ICU). Patients admitted ICUs by virtue being critically ill have a higher mortality than other hospitalized patients. This designed see if any improvement could be brought about certificates. Materials and Methods: Educating sessions, interactive workshops, monthly audits for...