A5101537826- Pregnancy and preeclampsia studies
- Preterm Birth and Chorioamnionitis
- Pregnancy-related medical research
- Reproductive System and Pregnancy
- Maternal and fetal healthcare
- Nanoparticle-Based Drug Delivery
- Prenatal Screening and Diagnostics
- Advanced Drug Delivery Systems
- Gestational Diabetes Research and Management
- Neonatal Respiratory Health Research
- Blood Coagulation and Thrombosis Mechanisms
- Assisted Reproductive Technology and Twin Pregnancy
- Ectopic Pregnancy Diagnosis and Management
- Birth, Development, and Health
- Wound Healing and Treatments
- Graphene and Nanomaterials Applications
- Natural Antidiabetic Agents Studies
- Bone Tissue Engineering Materials
- Electrospun Nanofibers in Biomedical Applications
- Computational Drug Discovery Methods
- Adipokines, Inflammation, and Metabolic Diseases
- biodegradable polymer synthesis and properties
- Cholinesterase and Neurodegenerative Diseases
- Neonatal and Maternal Infections
- Drug Solubulity and Delivery Systems
Chitkara University
2022-2024
Father Muller Medical College Hospital
2024
GITAM University
2024
Pandit Ravishankar Shukla University
2024
Banaras Hindu University
2016-2023
Indian Institute of Technology BHU
2016-2023
Chaitanya Bharathi Institute of Technology
2023
Institute of Engineering
2023
Desh Bhagat University
2021-2022
Maharishi Markandeshwar University, Mullana
2020-2022
Diabetes mellitus is most common disorder characterize by hyperglycemia. Chronic hyperglycemia may lead to over production of free radicals thereby results in oxidative stress which impaired healing wounds. Ferulic acid (FA) has been shown have antidiabetic and antioxidant properties. The aim the present study was develop nanoparticles its hypoglycemic wound activities. acid-poly(lactic-co-glycolic acid) (FA-PLGA) were prepared nano precipitation method. FA-PLGA had an average size 240 nm....
Abstract Objectives To determine the clinical significance of presence amniotic fluid (AF) ‘sludge’ among asymptomatic patients at high risk for spontaneous preterm delivery. Methods This retrospective case–control study included 281 with ( n = 66) or without 215) AF ‘sludge’, who underwent transvaginal ultrasound examination between 13 and 29 completed weeks gestation. Patients threatened labor, multiple gestation, fetal anomalies, placenta previa uterine contractions were excluded. Results...
Microbial infection and oxidative damage of the fibroblast often results in prolonged incomplete wound healing. Therefore, there is an increasing demand for a scaffold being effective to prevent any possible neutralize excessively released free radicals. Herein, we designed PCL-based nanofiber loaded with ciprofloxacin hydrochloride (CHL) quercetin. Developed showed formation smooth continuous 101.59 ± 29.18 nm average diameter entrapping drugs amorphous form without physico-chemical...
Objective: Infection has been implicated in the pathogenesis of preeclampsia, yet association between microbial invasion amniotic cavity (MIAC) and preeclampsia not determined. The aim this study was to determine prevalence, diversity associated with MIAC, as well nature host response MIAC patients preeclampsia.
Objective: Microbial invasion of the amniotic cavity (MIAC) has been detected in women with preterm labor, prelabor rupture membranes (PROM), and patients at term PROM or spontaneous labor. Intrauterine infection is recognized as a potential cause fetal growth restriction; yet, frequency MIAC pregnancies small-for-gestational-age (SGA) fetuses unknown. The aim this study was to determine frequency, diversity relative abundance microbes fluid (AF) an SGA neonate using combination culture...
Intrauterine devices (IUDs) are used for contraception worldwide; however, the management of pregnancies with an IUD poses a clinical challenge. The purpose this study was to determine outcome pregnancy in patients IUD.
Obesity, insulin resistance, and dyslipidemia are associated with preeclampsia. Recently, "adipose tissue failure", characterized by dysregulation of adipokine production, has been implicated in the pathophysiology these metabolic complications. Adiponectin, an insulin-sensitizing, anti-atherogenic, anti-inflammatory angiogenic adipokine, circulates oligomeric complexes including: low-molecular-weight (LMW) trimers, medium-molecular-weight (MMW) hexamers high-molecular-weight (HMW) isoforms....
Quercetin (Qu), is a flavonoid known to have anti-diabetic effects owing its antioxidant property, thus promoting regeneration of the pancreatic islets, ultimately increasing insulin secretion. But therapeutic application Qu hampered by low oral bioavailability and unfavourable physicochemical characteristics. The present work aimed at formulation loaded Soluplus® micelles (SMs) so as enhance provide prolonged release for management diabetes. Box-Behnken response surface methodology was...
Objective: To propose a theoretical formulation of engeletin-nanostructured lipid nanocarriers for improved delivery and increased bioavailability in treating Huntington's disease (HD). Methods: We conducted literature review the pathophysiology HD limitations currently available medications. also reviewed potential therapeutic benefits engeletin, flavanol glycoside, through Keap1/nrf2 pathway. then proposed across blood-brain barrier (BBB) bioavailability. Results: is an autosomal dominant...
Real-time object detection is a critical task in edge computing applications, where low latency and energy efficiency are paramount. This paper proposes hybrid YOLO-based FPGA architecture optimized for real-time at the edge. The combines computational of hardware accelerators with flexibility software-based post-processing to achieve balance between performance adaptability. proposed system offloads compute-intensive convolutional layers fabric, leveraging parallel processing capabilities...
Background: There is increase in caesarean section (CS) rate worldwide. As per WHO CS are should be 10-15%. The present study undertaken to know the incidence of at a tertiary centre and also analyse cases as Robsons 10 group classification system. Methods: A prospective observational was conducted department obstetrics gynaecology GIMS Kalaburagi from January 2023 December 2023. All pregnant women gestational age 28 weeks or more admitted labour room delivered taken into this study....
Abstract Objective The aim of this study was to determine whether the risk early spontaneous preterm delivery (PTD) in asymptomatic women with a sonographic cervical length ≤ 15 mm mid‐trimester changes as function gestational age at diagnosis. Methods This cohort included 109 patients diagnosed 14–24 weeks gestation. Women multifetal gestation, cerclage and dilatation > 2 cm were excluded. population stratified by diagnosis (< 20 vs. 20–24 weeks) (≤ 10 11–15 mm). primary outcome...
Fetal death can lead to disseminated intravascular coagulation or fetal syndrome. However, currently it is not clear what are the changes in system patients with a without This study was undertaken determine: (1) whether absence of syndrome associated hemostatic markers maternal plasma and amniotic fluid; (2) hypertension placental abruption further profile these patients.A cross-sectional included following: determination platelet activation normal pregnancy (n = 71) demise (FD) 65); fluid...
Lee J, Romero R, Dong Z, Xu Y, Qureshi F, Jacques S, Yoo W, Chaiworapongsa T, Mittal P, Hassan S & Kim C J (2011) Histopathology 59 , 928–938 Unexplained fetal death has a biological signature of maternal anti‐fetal rejection: chronic chorioamnionitis and alloimmune anti‐human leucocyte antigen antibodies Aims: Chronic is histological manifestation cellular rejection. As failure graft survival the most catastrophic event in organ transplantation, we hypothesized that could be consequence...