A5034976288- Essential Oils and Antimicrobial Activity
- Advanced Drug Delivery Systems
- Polysaccharides Composition and Applications
- Computational Drug Discovery Methods
- Drug Solubulity and Delivery Systems
- Natural Antidiabetic Agents Studies
- Pharmacology and Nanomedicine Research
- Phytochemicals and Antioxidant Activities
- Polysaccharides and Plant Cell Walls
- Pharmacological Effects of Natural Compounds
- Drug-Induced Hepatotoxicity and Protection
- Diverse Scientific Research Studies
- Advancements in Transdermal Drug Delivery
- Piperaceae Chemical and Biological Studies
- Moringa oleifera research and applications
- Nanoparticle-Based Drug Delivery
- Cholinesterase and Neurodegenerative Diseases
- Genetic Neurodegenerative Diseases
- Toxin Mechanisms and Immunotoxins
- Nigella sativa pharmacological applications
- Tryptophan and brain disorders
- Hops Chemistry and Applications
- Lipid Membrane Structure and Behavior
- Phytochemicals and Medicinal Plants
- Graphene and Nanomaterials Applications
Tishk International University
2019-2024
JSS Academy of Higher Education and Research
2015
Technology Information, Forecasting and Assessment Council
2012-2014
Indian Institute of Management Indore
2014
National Institute of Pharmaceutical Education and Research
2014
Polymers from natural sources are widely used as excipients in the formulation of pharmaceutical dosage forms. The objective this study was to extract and further characterize tamarind gum polysaccharide (TGP) obtained Tamarindus indica an excipient for biomedical applications. Double distilled water a solvent extraction while Ethyl alcohol antisolvent precipitation. results Hausner ratio, Carr’s index angle repose were found be 0.94, 6.25, 0.14, respectively, which revealed that powder is...
Purpose: The present study was intended to fabricate chitosan (Ch)-tamarind gum polysaccharide (TGP) polyelectrolyte complex stabilized cubic nanoparticles of simvastatin and evaluate their potential against human breast cancer cell lines. Materials Methods: antisolvent precipitation method used for formulation nanoparticles. Factorial design (3 2 ) utilized as a tool analyze the effect Ch TGP concentration on particle size entrapment efficiency Results: Formulated showed high (67.19± 0.42–...
The purpose of the present study was to develop emulsions encapsulated by chitosan on outer surface a nano droplet containing 5-fluorouracil (5-FU) as model drug. were characterized in terms size, pH and viscosity evaluated for their physicochemical properties such drug release skin permeation vitro. tween 80 (T80), sodium lauryl sulfate, span 20, combination polyethylene glycol (PEG) T20 exhibited 88%, 86%, 90% 92%, respectively. Chitosan-modified considerably controlled 5-FU compared...
Present study deciphers development of oral polysaccharide-based colon targeted solid self-nanoemulsifying drug delivery system (S-SNEDDS) xanthohumol (XH). Several studies have shown that XH has anti-inflammatory and antioxidant properties, suggesting it could be a good candidate for the treatment colorectal diseases (CRD). Despite its potential, low aqueous solubility. As result, bioavailability is constrained by dissolution rate. The liquid (L)-SNEDDS was constituted using Labrafac PG as...
Objective: To propose a theoretical formulation of engeletin-nanostructured lipid nanocarriers for improved delivery and increased bioavailability in treating Huntington's disease (HD). Methods: We conducted literature review the pathophysiology HD limitations currently available medications. also reviewed potential therapeutic benefits engeletin, flavanol glycoside, through Keap1/nrf2 pathway. then proposed across blood-brain barrier (BBB) bioavailability. Results: is an autosomal dominant...
The oldest remedies identified to mankind are herbal medicines. India is recognized worldwide for its Ayurvedic treatment. has rich history of using many plants medicinal purposes. Remedial cooperating extremely dynamic position in customary drugs the action a variety illness. However key obstacle, which hindered promotion use alternative medicines developed countries, no evidence documentation and absence stringent quality control measures. There demand every investigate effort execute on...
Development of self-nanoemulsifying drug delivery systems (SNEDDS) docosahexaenoic acid (DHA) is reported with the aim to achieve enhanced dissolution rate. The optimized composition liquid SNEDDS (L-SNEDDS) formulation was Labrafil M1944 CS, 47% v/v Tween 80, 27% Transcutol P, and 0.1% DHA. L-SNEDDS were solidified using Syloid XDP 3150 as solid porous carrier. droplet size, polydispersity index, zeta potential, percentage loading, cloud point for found be 43.51 ± 1.36 nm, 0.186 0.053,...
Abstract: Drug discovery and development (DDD) is a highly complex process that necessitates precise monitoring extensive data analysis at each stage. Furthermore, the DDD both timeconsuming costly. To tackle these concerns, artificial intelligence (AI) technology can be used, which facilitates rapid of datasets within limited timeframe. The pathophysiology cancer disease complicated requires research for novel drug development. first stage in involves identifying targets. Cell structure...
Plant secondary metabolites possess excellent antioxidant properties and reported as important source of antioxidants in nutraceuticals. Rutin is one the plant having property. It majorly present tobacco, rue, buckwheat well some citrus fruits such grapes, lime, orange, lemon. As nutraceutical it useful treating osteoporosis, oxidative stress, inflammation, cancer diabetes. However, its therapeutic efficacy limited due to lipophilicity that further causes dissolution rate oral...
The aim of present study was to introduce the role quality by design produce curcumin crystals with enhanced dissolution rate and bioavailability. liquid antisolvent method used crystals. crystal growth controlled using Box–Behnken design. variables in crystallization process included ratio pyrocatechol polyethylene glycol (PEG) 1500, solvent addition rate, stirring time, speed. Combination these found yield 2.45 ± 0.56 μm size 0.321 polydispersity index that exhibited solubility, product...