Subheet Kumar Jain

ORCID: 0000-0003-2272-941X
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About
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Research Areas
  • Advancements in Transdermal Drug Delivery
  • Advanced Drug Delivery Systems
  • Drug Solubulity and Delivery Systems
  • Nanoparticle-Based Drug Delivery
  • Dermatology and Skin Diseases
  • Bee Products Chemical Analysis
  • Synthesis and biological activity
  • Pharmacogenetics and Drug Metabolism
  • Retinal Diseases and Treatments
  • Essential Oils and Antimicrobial Activity
  • Fatty Acid Research and Health
  • Nail Diseases and Treatments
  • Drug-Induced Hepatotoxicity and Protection
  • Hydrogels: synthesis, properties, applications
  • RNA Interference and Gene Delivery
  • Computational Drug Discovery Methods
  • Eicosanoids and Hypertension Pharmacology
  • Cancer Treatment and Pharmacology
  • Analytical Methods in Pharmaceuticals
  • Helicobacter pylori-related gastroenterology studies
  • Lipid Membrane Structure and Behavior
  • Synthesis of Organic Compounds
  • Retinal Imaging and Analysis
  • Pharmacological Effects of Natural Compounds
  • Acne and Rosacea Treatments and Effects

Indo Soviet Friendship College of Pharmacy
2025

Central Institute for Research on Buffaloes
2025

Guru Nanak Dev University
2015-2024

Indian Institute of Management Amritsar
2015-2018

GTx (United States)
2012-2018

Indian Institute of Integrative Medicine
2018

Punjabi University
2005-2013

Marymount University
2012

Dr. Hari Singh Gour University
2002-2006

Indian Institute of Technology Kharagpur
2006

This work describes the use of a novel vesicular drug carrier system called transfersomes, which is composed phospholipid, surfactant, and water for enhanced transdermal delivery. The transfersomal was much more efficient at delivering low high molecular weight to skin in terms quantity depth. In present study transfersomes liposomes were prepared by using dexamethasone as model drug. evaluated vitro vesicle shape size, entrapment efficiency, degree deformability, number vesicles per cubic...

10.1081/ddc-120025458 article EN Drug Development and Industrial Pharmacy 2003-01-01

Pyran-based heterocycles are promising for anticancer drug discovery.

10.1039/c7ra05441f article EN cc-by-nc RSC Advances 2017-01-01

Macrophages of the reticuloendothelial system and brain act as major reservoir for HIV because their long term survival after infection ability to spread virus particles bystander CD4 positive lymphocyte cells. The objective present study was investigate mannan-coated nanoparticles macrophage targeting didanosine. Different didanosine loaded were prepared using double desolvation technique characterized in vitro, ex vivo vivo. Results cellular uptake indicated 5-fold higher from formulation...

10.2478/v10007-007-0045-1 article EN cc-by-nc-nd Acta Pharmaceutica 2008-01-01

Diseases and disorders of the brain are extremely difficult to treat pharmacologically because most drugs unable pass across blood–brain barriers. Complex multi-strand tight junctions between adjacent cerebral endothelial cells choroid plexus epithelial form a physical barrier prevent passage water soluble from blood into brain, whereas inward lipid is restricted by drug efflux pumps which act as functional barrier. In present work, transferrin-coupled liposomal system for delivery...

10.1080/10611860500107401 article EN Journal of drug targeting 2005-05-01

Luliconazole is a new drug candidate for treatment of topical fungal infections. Its present therapy associated with limitations very poor and slow skin permeation, leading to required long term repeated administration complete cure disease. Lipid nanocarriers based elastic lipogel ethogel formulations were developed in strength 1% w/w extensively characterized vitro, ex-vivo, vivo compared their results the marketed formulation. The prepared found have ideal pH, nanometric vesicle size,...

10.1080/08982104.2019.1682602 article EN Journal of Liposome Research 2019-10-21

Development of self-nanoemulsifying drug delivery systems (SNEDDS) glimepiride is reported with the aim to achieve its oral delivery. Lauroglycol FCC, Tween-80, and ethanol were used as oil, surfactant, co-surfactant, respectively independent variables. The optimized composition SNEDDS formulation (F1) was 10% v/v 45% Tween 80, ethanol, 0.005% w/v glimepiride. Further, liquid solidified through spray drying using various hydrophilic hydrophobic carriers. Among carriers, Aerosil 200 found...

10.1080/03639045.2018.1431656 article EN Drug Development and Industrial Pharmacy 2018-01-23

The aim of the present study was to prepare and characterize novel vesicular carrier elastic liposomes, most commonly used non-steroidal anti-inflammatory agent diclofenac for its sustained targeted delivery. Elastic liposomes were prepared characterized in vitro vivo. effect different formulation variables like type surfactant, concentration surfactant dose drug on transdermal flux, amount deposited into skin, muscle plasma investigated. biological activity optimized evaluated using...

10.2174/1567201054368020 article EN Current Drug Delivery 2005-07-01

Docosahexaenoic Acid (DHA) supplementation is regarded as safe and beneficial to maternal health before, during, after pregnancy. DHA indeed an important fatty acid, its requirement elevated during pregnancy due fetal brain eye development requirements. Despite established importance, there no Recommended Dietary Allowance (RDA) for DHA, unlike other essential nutrients. The gap in the estimated average minimum required intake individual differences needs of among individuals. This depends...

10.2174/0115734013338932241204040840 article EN Current Nutrition & Food Science 2025-01-22
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