Shubham Thakur

ORCID: 0000-0001-5857-2624
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About
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Research Areas
  • Ruminant Nutrition and Digestive Physiology
  • Advanced Drug Delivery Systems
  • Nanoparticle-Based Drug Delivery
  • Advancements in Transdermal Drug Delivery
  • Fatty Acid Research and Health
  • Genetic and phenotypic traits in livestock
  • Drug Solubulity and Delivery Systems
  • Animal Nutrition and Physiology
  • Agricultural Science and Fertilization
  • Livestock Management and Performance Improvement
  • Crop Yield and Soil Fertility
  • Reproductive Physiology in Livestock
  • Agricultural pest management studies
  • RNA Interference and Gene Delivery
  • Dermatology and Skin Diseases
  • Neonatal Respiratory Health Research
  • Autopsy Techniques and Outcomes
  • Rice Cultivation and Yield Improvement
  • Meat and Animal Product Quality
  • Inhalation and Respiratory Drug Delivery
  • Electrospun Nanofibers in Biomedical Applications
  • Computational Drug Discovery Methods
  • Food Security and Health in Diverse Populations
  • Eicosanoids and Hypertension Pharmacology
  • Agronomic Practices and Intercropping Systems

Indo Soviet Friendship College of Pharmacy
2024-2025

Guru Nanak Dev University
2019-2024

Chaudhary Sarwan Kumar Himachal Pradesh Krishi Vishvavidyalaya
2023

Central Institute for Research on Buffaloes
2023

Institute of Himalayan Bioresource Technology
2023

Panjab University
2022

Punjab Engineering College
2022

University of Mumbai
2021-2022

Lala Lajpat Rai University of Veterinary and Animal Sciences
2021

Indian Council of Agricultural Research
2019

Fibromyalgia (FM) is a chronic musculoskeletal disorder characterised by widespread pain, fatigue, sleep disturbances, and cognitive dysfunction. Conventional treatment primarily focuses on symptomatic relief through pharmacological interventions, often with limited success. Ayurveda, the ancient Indian system of medicine, offers holistic approach addressing underlying imbalance Vata dosha, reducing Ama (toxins), enhancing Ojas (vital energy). Ayurvedic interventions such as Panchakarma...

10.46607/iamj1813032025 article EN International Ayurvedic Medical Journal 2025-03-12

Objective The study aimed to formulate and optimize Lapatinib-loaded calcium pectinate nanoparticles (LAP-PEC-NPs) using central composite design (CCD), evaluate their physicochemical properties, compare anticancer efficacy with raw LAP on MCF7 breast cancer cell lines.Significance of Review is significant as it successfully developed LAP-PEC-NPs through systematic optimization. These exhibited favorable high drug entrapment, sustained release. effective inhibition growth by underscores...

10.1080/03639045.2025.2485311 article EN Drug Development and Industrial Pharmacy 2025-04-02

Abstract: Paracellular transport is the movement of pharmaceuticals across biological membranes, which acts as a major barrier to drug delivery and sometimes limits efficacy therapeutic agents. Liposomes other lipid vesicles have emerged one most promising pharmaceutical carriers because their inherent biocompatibility ability trap both hydrophilic lipophilic drugs. Drug release and, hence, permeation through target membranes for often blocked by steadily impermeable nature bilayers. This...

10.2174/0115748855381844250317064852 article EN Current Drug Therapy 2025-04-04

Nutraceuticals, functional foods, immunity boosters, microcapsules, nanoemulsions, edible packaging, and safe food are the new progressive terms, adopted to describe industry. Also, rising awareness among consumers regarding these has created an opportunity for manufacturers scientists worldwide use as a delivery vehicle. Packaging performs very imminent role in supply chain well it is consequential part of process manufacturing. Edible packaging swiftly emerging art science which...

10.3389/fsufs.2021.734921 article EN cc-by Frontiers in Sustainable Food Systems 2021-10-26

M astitis, an inflammatory reaction of the mammary gland, is regarded as most common infectious disease dairy cows resulting in considerable economic losses for both farmers and milk processors (Halasa et al., 2007; Geary 2012).It characterized by physical, chemical bacteriological changes pathological transformations glandular tissue udder.Almost all cases bovine mastitis are associated with bacteria; however yeasts, fungi or algae may also be involved (Hogan 1999).Mastitis initiated after...

10.17582/journal.jahp/2018/6.1.18.26 article EN Journal of Animal Health and Production 2018-01-01

In continuous efforts to develop anti-Alzheimer's agents, we rationally designed and synthesized a series of multitargeting molecules by incorporating the essential molecular features standard drug donepezil. Among series, compound 4b showed properties act as an agent, which is better tolerable in vivo than Acetylcholinesterase (AChE) inhibition data that inhibits enzyme with half-maximal inhibitory concentration (IC50) value 0.78 μM also DNA protection, was confirmed through nicking assay,...

10.1021/acschemneuro.1c00535 article EN ACS Chemical Neuroscience 2022-02-23

Docetaxel (DTX) is a highly lipophilic, BCS class IV drug with poor aqueous solubility (12.7 µg/mL). Presently, only injectable formulation available in the market which uses large amount of surfactant (Tween 80) and dehydrated alcohol as solubilizer. High concentrations Tween 80 formulations are associated severe consequences i.e. nephrotoxicity, fluid retention, hypersensitivity reactions. The present study aims to eliminate 80, thus novel biocompatible Vitamin E TPGS based nanovesicle DTX...

10.1080/08982104.2020.1835955 article EN Journal of Liposome Research 2020-10-14

Abstract Background The present study focused on developing a superior adsorbent carrier (microparticles) to solidify the self-emulsifying drug delivery system. two approaches, solvent evaporation and spray drying, were explored synthesize microparticles using chitosan (CH) EDTA disodium. 3 2 full factorial design was applied optimize microparticle process produced by both methods. Results various characterization evaluations of revealed amide linkages between CH disodium, XRD results showed...

10.1186/s43094-024-00588-3 article EN cc-by Future Journal of Pharmaceutical Sciences 2024-02-12

Abstract: Total Parenteral Nutrition (TPN) is a method of providing nutrients directly into the bloodstream for individuals who are unable to meet their nutritional needs through normal digestive process or gastrointestinal system. It provides macronutrients and micronutrients in single container, reducing handling contamination risks making it more cost-effective. TPN has potential be used as drug delivery system, with applications combination therapies, personalized medicine, integrating...

10.2174/0113894501284598240226102943 article EN Current Drug Targets 2024-03-08

Abstract: Scalp psoriasis is a common manifestation of that significantly impacts patient's quality life. About 80% cases involve the scalp, making it most frequently affected area body. The treatment scalp particularly crucial because its hard-to-treat nature and substantial adverse on overall well-being. Along with physical symptoms discomfort itching, psoriasis, especially when affects can cause severe psychological damage. Treating be challenging due to location associated symptoms, such...

10.2174/0113894501292755240304063020 article EN Current Drug Targets 2024-03-19
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