Rajan Kumar

ORCID: 0000-0002-3339-1816
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About
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Research Areas
  • Flavonoids in Medical Research
  • Drug Solubulity and Delivery Systems
  • Phytochemistry and Biological Activities
  • Curcumin's Biomedical Applications
  • Natural Antidiabetic Agents Studies
  • Medicinal Plants and Neuroprotection
  • Analytical Chemistry and Chromatography
  • Analytical Methods in Pharmaceuticals
  • Pharmacological Effects of Natural Compounds
  • Crystallization and Solubility Studies
  • Computational Drug Discovery Methods
  • Saffron Plant Research Studies
  • Cholinesterase and Neurodegenerative Diseases
  • Diabetic Foot Ulcer Assessment and Management
  • Polysaccharides Composition and Applications
  • Alzheimer's disease research and treatments
  • Wound Healing and Treatments
  • Nitric Oxide and Endothelin Effects
  • Phytochemistry and biological activity of medicinal plants
  • Polysaccharides and Plant Cell Walls
  • Chromatography in Natural Products
  • IoT and Edge/Fog Computing
  • Gut microbiota and health
  • Hops Chemistry and Applications
  • Nanoparticles: synthesis and applications

Lovely Professional University
2017-2024

All India Institute of Medical Sciences, Deoghar
2023-2024

Indian Institute of Technology Roorkee
2010-2022

Birla Institute of Technology, Mesra
2018-2022

Hindustan Institute of Technology and Science
2021

Dr. B. R. Ambedkar National Institute of Technology Jalandhar
2021

University of Wollongong
2014

Jawaharlal Nehru University
2014

Detection and prediction of the novel Coronavirus present new challenges for medical research community due to its widespread across globe. Methods driven by Artificial Intelligence can help predict specific parameters, hazards, outcomes such a pandemic. Recently, deep learning-based approaches have proven opportunity determine various difficulties in prediction. In this work, two learning algorithms, namely reinforcement learning, were developed forecast COVID-19. This article constructs...

10.3389/fpubh.2021.744100 article EN cc-by Frontiers in Public Health 2021-10-04

Present study deciphers development of oral polysaccharide-based colon targeted solid self-nanoemulsifying drug delivery system (S-SNEDDS) xanthohumol (XH). Several studies have shown that XH has anti-inflammatory and antioxidant properties, suggesting it could be a good candidate for the treatment colorectal diseases (CRD). Despite its potential, low aqueous solubility. As result, bioavailability is constrained by dissolution rate. The liquid (L)-SNEDDS was constituted using Labrafac PG as...

10.3390/pharmaceutics14112384 article EN cc-by Pharmaceutics 2022-11-05

Telmisartan (TLM), a nonpeptide angiotensin II antagonist, is widely prescribed for treating arterial hypertension and marketed by the innovator with trade name of Micardis plus. exhibits low aqueous solubility in pH range 3-7, which physiological pH. For addressing issue poor TLM, its commercial form makes use inorganic alkalinizers. The present work illustrates attempt to improve telmisartan via crystal engineering approach. A novel solid phthalic acid was obtained through solution...

10.1021/acsomega.8b02144 article EN publisher-specific-oa ACS Omega 2018-11-13

Development of self-nanoemulsifying drug delivery systems (SNEDDS) docosahexaenoic acid (DHA) is reported with the aim to achieve enhanced dissolution rate. The optimized composition liquid SNEDDS (L-SNEDDS) formulation was Labrafil M1944 CS, 47% v/v Tween 80, 27% Transcutol P, and 0.1% DHA. L-SNEDDS were solidified using Syloid XDP 3150 as solid porous carrier. droplet size, polydispersity index, zeta potential, percentage loading, cloud point for found be 43.51 ± 1.36 nm, 0.186 0.053,...

10.1080/03639045.2020.1742143 article EN Drug Development and Industrial Pharmacy 2020-03-12

• RP-HPLC method for fisetin was developed in rat plasma. The validated as per ICH guidelines. Method found linear the concentration range of 25–125 ng/mL. Recovery above 95% and % RSD less than 2 indicated about accuracy precision method. Absence interfering peaks at retention times quercetin method's specificity. Fisetin is an important phyto-flavonoid that possesses very good anti-oxidant, anti-Parkinson's anti-cancer activities. A bioanalytical estimation rat's plasma using reverse phase...

10.1016/j.sajb.2020.05.010 article EN cc-by South African Journal of Botany 2020-06-03
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