A5086888245- Drug Solubulity and Delivery Systems
- Flavonoids in Medical Research
- Natural product bioactivities and synthesis
- Advanced Drug Delivery Systems
- Analytical Chemistry and Chromatography
- Chromatography in Natural Products
- Crystallization and Solubility Studies
- Nanoparticle-Based Drug Delivery
- Phytochemistry and Biological Activities
- Polysaccharides Composition and Applications
Lovely Professional University
2020-2024
Development of self-nanoemulsifying drug delivery systems (SNEDDS) docosahexaenoic acid (DHA) is reported with the aim to achieve enhanced dissolution rate. The optimized composition liquid SNEDDS (L-SNEDDS) formulation was Labrafil M1944 CS, 47% v/v Tween 80, 27% Transcutol P, and 0.1% DHA. L-SNEDDS were solidified using Syloid XDP 3150 as solid porous carrier. droplet size, polydispersity index, zeta potential, percentage loading, cloud point for found be 43.51 ± 1.36 nm, 0.186 0.053,...
• RP-HPLC method for fisetin was developed in rat plasma. The validated as per ICH guidelines. Method found linear the concentration range of 25–125 ng/mL. Recovery above 95% and % RSD less than 2 indicated about accuracy precision method. Absence interfering peaks at retention times quercetin method's specificity. Fisetin is an important phyto-flavonoid that possesses very good anti-oxidant, anti-Parkinson's anti-cancer activities. A bioanalytical estimation rat's plasma using reverse phase...
Background: Chiral purity is a critical quality attribute of pharmaceutical materials as chiral compounds are known to exhibit different pharmacological and toxicological properties compared those their enantiomers (or diastereomers for molecules with multiple centers). It important note that about 40% the synthetic drugs chiral, 60% all pharmaceuticals 45% sold racemates. The objective current review discuss various chromatographic techniques used separation compounds. Methods: Various...