Natascha Del Vecchio

ORCID: 0000-0003-2092-8001
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About
Contact & Profiles
Research Areas
  • HIV/AIDS Research and Interventions
  • HIV, Drug Use, Sexual Risk
  • Adolescent Sexual and Reproductive Health
  • LGBTQ Health, Identity, and Policy
  • HIV Research and Treatment
  • Bioinformatics and Genomic Networks
  • Social Media and Politics
  • Data-Driven Disease Surveillance
  • Gene expression and cancer classification
  • Bayesian Methods and Mixture Models
  • COVID-19 Impact on Reproduction
  • Prenatal Substance Exposure Effects
  • FOXO transcription factor regulation
  • Cardiovascular Health and Risk Factors
  • Syphilis Diagnosis and Treatment
  • Complex Network Analysis Techniques
  • Mental Health Research Topics
  • Health disparities and outcomes
  • Health, Environment, Cognitive Aging
  • Computational and Text Analysis Methods
  • Social Capital and Networks
  • Computational Drug Discovery Methods

University of Chicago
2021-2024

Chicago Department of Public Health
2023

Indo-American Center
2022

The University of Texas Health Science Center at Houston
2021

COVID-19 has disproportionately impacted vulnerable populations, including Black men who have sex with (BMSM) and transgender women (BTW). We investigated associations of stressors behaviors pre-exposure prophylaxis (PrEP) antiretroviral therapy (ART) among BMSM BTW.As part the Neighborhoods Networks (N2) study, we conducted virtual interviews during peak infectivity in Chicago BTW (April-July 2020). Survey questions included multilevel stressors, behaviors, current PrEP/ART use access....

10.1097/qai.0000000000002770 article EN JAIDS Journal of Acquired Immune Deficiency Syndromes 2021-07-26

// Arvand Asghari 1 , * Katherine Wall 2 Michael Gill Natascha Del Vecchio 3 Farnaz Allahbakhsh Jacky Wu Nan Deng 4 W. Jim Zheng 5 Hulin Michihisa Umetani 6 and Vahed Maroufy Center for Nuclear Receptors Cell Signaling, Department of Biology Biochemistry, University Houston, TX 77204, USA Biostatistics Data Science, School Public Health, UTHealth, 77030, Chicago HIV Elimination, Chicago, IL 60637, Clinical Cancer Prevention Department, Texas MD Anderson Center, Biomedical Informatics, Health...

10.18632/oncotarget.28225 article EN Oncotarget 2022-04-06

Abstract This study introduces an innovative methodological approach to identify potential drivers of structuring HIV-1 transmission clustering patterns between different subpopulations in the culturally and racially/ethnically diverse context Houston, TX, largest city Southern United States. Using 6332 pol sequences from persons newly diagnosed with HIV during period 2010–2018, we reconstructed clusters, using HIV-TRAnsmission Cluster Engine (HIV-TRACE); inferred demographic risk parameters...

10.1038/s41598-021-82673-8 article EN cc-by Scientific Reports 2021-02-08

Objective: Young MSM (YMSM) bear a disproportionate burden of HIV infection in the United States and their risks acquiring may be shaped by complex multilayer social networks. These networks are formed through not only direct contact with social/sex partners but also indirect anonymous contacts encountered when attending venues. We introduced new application state-of-the-art graph-based deep learning method to predict that can identify influential neighbors within these multiple network...

10.1097/qad.0000000000002784 article EN AIDS 2020-12-10

Substance use, particularly binge drinking of alcohol and noninjection substance is associated with increased risk for HIV infection among youth, but structured use screening brief intervention are not often provided as part reduction.

10.2196/43653 article EN cc-by JMIR Mental Health 2023-03-29

Abstract Detection of viral transmission clusters using molecular epidemiology is critical to the response pillar Ending HIV Epidemic initiative. Here, we studied whether inference with an incomplete dataset would influence accuracy reconstructed network. We analyzed sequence data available from ~ 13,000 individuals diagnosed (2012–2019) Houston Health Department surveillance 53% completeness (n = 6852 sequences). extracted random subsamples and compared resulting networks versus full-size...

10.1038/s41598-022-21924-8 article EN cc-by Scientific Reports 2022-11-10

<sec> <title>BACKGROUND</title> Social network data are essential and informative for public health research implementation as they provide details on individuals their social context. </sec> <title>OBJECTIVE</title> We aimed to generate a more complete sociocentric-like “fuzzy” by harmonizing alternative sources of egocentric digital examine relationships between participants in the N2 cohort study. Further, we propose peer effects status neutral HIV care continuum cascade....

10.2196/preprints.64497 preprint EN 2024-07-18

Social support has been associated with viral suppression among persons living HIV (PWH). We examined cross-sectional data from young Black men who have sex to see if sociodemographic factors, medical history, and egocentric Facebook social measures are related suppression. Differences between participants were using Chi-square, Fisher's exact, or Wilcoxon Rank Sum Tests, significance set at

10.3390/ijerph21101352 article EN International Journal of Environmental Research and Public Health 2024-10-12

Public health surveillance data used in HIV molecular cluster analyses lack contextual information that is available from partner services (PS) data. Integrating these sources retrospective can enrich understanding of the risk profile people clusters. In this study, clusters were identified and matched to on partners other gleaned at time diagnosis, including coinfection with syphilis. We aimed produce a more complete membership Houston, Texas, city ranking ninth nationally rate new...

10.1089/aid.2022.0088 article EN AIDS Research and Human Retroviruses 2023-02-14

Objectives: This study investigates primary peer-referral engagement (PRE) strategies to assess which strategy results in engaging higher numbers of people with HIV (PWH) who are virally unsuppressed. Design: We develop a modeling that simulates an epidemic (transmission, disease progression, and viral evolution) over 6 years using agent-based model followed by simulating PRE strategies. investigate two where referrals based on social network (SNS) or sexual partner contact tracing (SPCT)....

10.1097/qad.0000000000003767 article EN AIDS 2023-10-26

Black men who have sex with (BMSM) and transgender women (BTW) are disproportionately affected by incarceration HIV. We assessed factors associated HIV testing viral suppression among 176 incarcerated BMSM BTW in Chicago, IL; Los Angeles, CA; Houston, TX. In multivariable logistic regression, having a sexual orientation of bisexual, heterosexual, or other vs. gay same-gender loving was higher odds custody (aOR 8.97; 95% CI 1.95 - 41.24). Binge drinking 0.19; 0.04 0.92) being unemployed prior...

10.1080/09540121.2022.2094312 article EN AIDS Care 2022-07-17

<sec> <title>BACKGROUND</title> Substance use, particularly binge drinking of alcohol and noninjection substance is associated with increased risk for HIV infection among youth, but structured use screening brief intervention are not often provided as part reduction. </sec> <title>OBJECTIVE</title> The purpose the study was to test efficacy a fully automated electronic intervention, called Step Up, Test reduce misuse adolescents young adults presenting testing. Secondary objectives were...

10.2196/preprints.43653 preprint EN 2022-10-19

Abstract Objective(s) Young Black men who have sex with (YBMSM) are a key population identified in the Illinois Getting to Zero (GTZ) initiative experienced disproportionate HIV incidence. Rising stimulant use has been determined impede effectiveness of ART and pre-exposure prophylaxis for suppressing transmission populations. This modeling study explores impact on incidence among YBMSM – given limited development dedicated or culturally appropriate interventions this assesses these...

10.1101/2021.09.22.21263980 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2021-09-23

Abstract Breast cancer (BC) is the most common type of and second leading cancer-related cause death in women worldwide. Endocrine therapy an effective therapeutic approach for estrogen receptor (ER)-positive breast cancer; however, many cases, tumor regrowth occurs after becomes unresponsive anymore. While some gene mutations contribute to resistance patients, underlying causes endocrine therapies are mostly undetermined. In this study, we utilized our recently developed statistical...

10.21203/rs.3.rs-1047808/v1 preprint EN cc-by Research Square (Research Square) 2021-11-11
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