A5061755674- Urological Disorders and Treatments
- Sexual Differentiation and Disorders
- Urologic and reproductive health conditions
- Pediatric Urology and Nephrology Studies
- Testicular diseases and treatments
- Renal and related cancers
- Genital Health and Disease
- Congenital Anomalies and Fetal Surgery
- Sarcoma Diagnosis and Treatment
- Renal cell carcinoma treatment
- Urinary and Genital Oncology Studies
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Kidney Stones and Urolithiasis Treatments
- Sperm and Testicular Function
- Hernia repair and management
- Tissue Engineering and Regenerative Medicine
- Cardiac tumors and thrombi
- Sexual function and dysfunction studies
- Ureteral procedures and complications
- Urinary Tract Infections Management
- Neonatal Health and Biochemistry
- Vascular Tumors and Angiosarcomas
- Ethics and Legal Issues in Pediatric Healthcare
- Tumors and Oncological Cases
- COVID-19 Impact on Reproduction
Children's Hospital of Zhejiang University
2016-2025
Zhejiang University
2011-2021
National Clinical Research
2020
Boston Children's Hospital
2015
The purpose of this study is to analyze the histopathological features resected testicular remnant specimens, ascertain incidence presence either germ cells (GCs) or seminiferous tubules (SNTs), and assess whether surgical excision necessary. A total 332 boys with vanishing testis underwent removal unilateral remnants, age 7-164 months (median 25 months). Among cases, 212 (63.8%) were younger than 36 143 (66.5%) found have hypertrophied contralateral testes larger 1.6 cm in longitudinal...
Background Wilms tumor (WT) is the most common renal malignant in children. It occurs primarily at preschool age. The purpose of this review to present current standards diagnosis and treatment WT around world. Data sources All recent literature on were searched reviewed. Results Most cases with are sporadic. survival patients high (90%). Involvement mutidisciplinary collaborative groups WT. National Tumor Study Group (NWTSG)/Children’s Oncology (COG) International Society Paediatric (SIOP)...
The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome 2 (SARS-CoV-2) has spread to more than 100 countries. Children approved be susceptible SARS-CoV-2 infection. Preventing and controlling the epidemic while ensuring orderly flows pediatric surgery clinical work proven a big challenge for both patients clinicians during epidemic. Based on transmission characteristics requirements prevention control COVID-19, authors proposed some concrete measures...
This study aimed to evaluate the medium and long-term outcomes of tunneled labial mucosa tube graft urethroplasty in treatment primary severe hypospadias failed hypospadias. We retrospectively reviewed medical records patients who underwent at a single center between 2007 2020. Data collected included patient demographic, operative post-operative characteristics. The surgical procedure was performed two stages. Binary logistic regression model used identify risk factors for postoperative...
Necrotizing enterocolitis (NEC) is a life-threatening inflammatory disease in newborns, but the mechanisms remain unclear. Interferon regulatory factor 5 (IRF5) master regulator of macrophage function and essential for proinflammatory M1 polarization. Our previous data indicated that macrophages promote NEC injury. Here, we investigated whether IRF5 involved pathogenesis NEC. First, found was upregulated infiltrated human neonates with compared to controls. We further confirmed upregulation...
To find a new appropriate evaluation for urethral plate quality in hypospadias repair, with particular interest the width proportion of to glans, serving as an appraisal index.Data were prospectively collected from prepubertal boys who underwent primary tubularized incised repair between January 2014 and April 2016 one center. Intrinsic parameters penis (meatal location, glans width, curvature degree) measured during operation. Urethroplasty complications recorded follow up. The correlation...
IntroductionComplications remain the top evaluation priority subsequent to hypospadias repair. Complications vary in further management, and usually require one or more reoperations. Patients and/or their parents concern not only with success rate of reoperation, but also risk numerous reoperations.ObjectiveTo identify factors associated reoperations following primary repair.Study designData were collected retrospectively from patients who underwent for complications repair at a single...
To compare the characteristics of conventional laparoscopic pyeloplasty (LP) and robotic-assisted (RALP) in infants young children with ureteropelvic junction obstruction (UPJO).We performed a retrospective study patients (age: 0-36 months) who underwent dismembered (Anderson-Hynes) fourth-generation RALP or traditional LP between April 2020 December 2020.A total 33 UPJO were enrolled: 12 (9 left side; 3 right side) 21 (18 side). In group, median patient age was 17 months (range: 5-36...
The present study evaluated the prognostic value of three‑dimensional ultrasound for fetal hydronephrosis. Pregnant females with hydronephrosis were enrolled and a novel indicator, renal parenchymal volume/kidney volume, was introduced to predict postnatal prognosis in comparison commonly used indicators. All indicators could whether surgery required hydronephrosis; however, predictive performance volume measurements as an individual indicator highest. In conclusion, is important predicting...
Persistent Müllerian duct syndrome (PMDS) is a rare clinically and genetically overlapping disorder caused by mutations in the anti-Müllerian hormone ( AMH ) gene or receptor type 2 AMHR2 gene. Affected individuals present uterus tubes normally virilized males are discovered unexpectedly during other surgeries. Since it complex, definitive clinical diagnosis can be missed, there no guidelines regarding how to deal with uterus. In study, exome sequencing Sanger verification were performed for...
Inflammatory myofibroblastic tumor (IMT) is an uncommon lesion with variable clinical behaviors from benign to mimicking malignant tumors. On rare occasions, IMT may exhibit transformation, and the strategy of remained undetermined. Herein, we report extremely unusual case transformation urinary bladder in a 14-year-old boy characterized by local aggressive behavior was successfully treated combined surgery perioperative chemotherapy.
Disorders of sexual development (DSD) refer to the congenital abnormalities chromosomes, gonads, or gender anatomy. Children with DSD usually experience more stress. The present study aims evaluate mental health status children DSD, and explore potential relevant factors. We included 30 age- gender-matched without as control group. All their parents completed scales Hamilton Anxiety Scale (HAMA). over 8 years old (