A5090304286- Heart Failure Treatment and Management
- Cardiac Structural Anomalies and Repair
- Transplantation: Methods and Outcomes
- Cardiovascular Function and Risk Factors
- Mechanical Circulatory Support Devices
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Cardiomyopathy and Myosin Studies
- Viral Infections and Immunology Research
- GDF15 and Related Biomarkers
- Cardiac Arrhythmias and Treatments
- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Renal Transplantation Outcomes and Treatments
- Cardiac tumors and thrombi
- Coronary Artery Anomalies
- Cardiac Valve Diseases and Treatments
- Nutrition and Health in Aging
- Infective Endocarditis Diagnosis and Management
- Neuropeptides and Animal Physiology
- Ultrasound in Clinical Applications
- Congenital Heart Disease Studies
- Cardiac Arrest and Resuscitation
- Central Venous Catheters and Hemodialysis
- Medication Adherence and Compliance
Chulalongkorn University
2015-2025
Thai Red Cross Society
2015-2025
King Chulalongkorn Memorial Hospital
2015-2025
Loma Linda University
2023
Saint Francis Hospital
2021
Bassett Healthcare Network
2021
Einstein Medical Center Philadelphia
2021
Agruicultural Research Institute
2017
Oregon Health & Science University
2012
Pacific Rim Electrophysiology Research Institute
2011
The underlying electrophysiological mechanism that causes an abnormal ECG pattern and ventricular tachycardia/ventricular fibrillation (Vt/VF) in patients with the Brugada syndrome (BrS) remains unelucidated. However, several studies have indicated right outflow tract (RVOT) is likely to be site of substrate. We hypothesized BrS who frequent recurrent VF episodes, substrate RVOT, either over epicardium or endocardium; electrograms would identified at this location, which serve as target for...
Abstract Background Acute heart failure (AHF) is a potentially life-threatening clinical syndrome, usually requiring hospital admission. Growth Differentiation Factor-15 (GDF-15) distant member of the transforming growth factor-β. The increased expression GDF-15 has been observed during (HF) and associated with worse outcomes. However, relationship between AHF not well understood limited evidence among Thai patients. Purpose Investigate correlation biomarker levels (measured upon admission...
ABSTRACT Since 1987, King Chulalongkorn Memorial Hospital (KCMH) has performed a substantial number of heart transplants as specific therapy for advanced‐stage failure. This descriptive study aimed to analyze post‐transplant survival in the recent era compared earlier periods and examine pharmacogenetics related immunosuppressants. Data from all recipients who underwent 1987 2021 were retrospectively retrieved electronic medical record. The genotypes relevant pharmacogenes analyzed alive...
To determine the prevalence, right ventricular (RV) characteristics, and outcomes of primary isolated RV failure (PI-RVF) after heart transplant (HTX). PI-RVF was defined as (1) need for mechanical circulatory support post-transplant, or (2) evidence RVF post-transplant measured by atrial pressure (RAP) > 15 mmHg, cardiac index < 2.0 L/min/m2 inotrope 72 h, pulmonary capillary wedge 18 transpulmonary gradient mmHg with systolic 50 mmHg. can be diagnosed from first 24-72 h completion...
We prospectively studied efficacy and safety outcomes of two 10-mg doses intravenous basiliximab on day 0 4 for induction therapy in 17 consecutive de novo heart transplant recipients. By the 2-week assessment post-transplant, there were no deaths, graft failures, or acute cellular rejections (ACRs) ISHLT grade ≥ 2R. 1-year 1 (6%) infectious death, 2 (12%) 2R ACRs, 6 (35%) asymptomatic cytomegalovirus (CMV) infections, (25%) treated infections. Our study was first to show that low-dose...
Background . White-coat hypertension (HT), masked HT, HT with white-coat effect, and uncontrolled are well-recognized problems of over- undertreatment high blood pressure in real-life practice. However, little is known about the true prevalence Thailand. Objectives To examine characteristics each subtype defined by mean home (HBP) clinic (CBP) using telemonitoring technology Thai hypertensives. Methods A multicenter, observational study included adult hypertensives who had been diagnosed for...
Abstract Objectives Our study aimed to determine the prevalence and prognosis of acute coronary syndrome with non-obstructive artery (ACS-NOCA) in patients hypertrophic cardiomyopathy (HCM). Methods results We enrolled a total 200 consecutive HCM over 139-month period from 2002 2013. The found that 28 (14% overall patients, 51% ACS) had ACS-NOCA, 18 (9% 86% MI) MINOCA as initial clinical presentations. highest disease (NOCA) was ST-elevation myocardial infarction (STEMI) (100%), followed by...
CoronaVac is an inactivated coronavirus disease (COVID-19) vaccine that was granted emergency authorization by the World Health Organization in June 2021. We present two cases of patients presenting with chest pain, abnormal electrocardiography, and elevated troponin consistent non-ST-elevation myocardial infarction within 24 hours after receiving COVID-19 vaccine.
Registries of patients hospitalized with acute heart failure (AHF) provided useful description characteristics and outcomes. However, a contemporary registry which provides sufficient evidence on outcomes after discharge is needed.The study aims to identify 1-year clinical prognostic predictors AHF.This retrospective enrolled who were due principal diagnosis AHF in tertiary care center Thailand between July 2017 June 2019. Baseline hospital courses the deceased survivors at 1 year compared....
Background We sought to investigate the impact of COVID-19 pandemic and Tele-HF Clinic (Tele-HFC) program on cardiovascular death, heart failure (HF) rehospitalization, transplantation rates in a cohort ambulatory HF patients during after peak pandemic. Methods Using clinic database, we compared data with before, during, (January 1 March 17 [pre-COVID], May 31 [peak-COVID], June October [post-COVID]). During peak-COVID, all were managed by Tele-HFC or hospitalization. After 1, chose either...
Elevated levels of high-sensitivity cardiac troponin (hs-cTn) are suggestive myocardial cell injury and coronary artery disease. We explored the association between hs-cTn subclinical arteriosclerosis using calcification (CAC) scoring among 337 virally suppressed patients with human immunodeficiency virus (HIV) who were ≥50 years old without evidence known disease.Noncontrast computed tomography blood sampling for hs-cTn, both subunit I (hs-cTnI) T (hs-cTnT), performed. The relationship CAC...
This Delphi method of consensus was designed to develop scientific statements for β-blockers in the continuum cardiovascular diseases with a special focus on role bisoprolol.
Abstract Funding Acknowledgements Type of funding sources: Public hospital(s). Main source(s): Ratchadapiseksomphotch Fund, Faculty Medicine, Chulalongkorn University Background Growth Differentiation Factor-15 (GDF-15) is a distant member the transforming growth factor-β (TGF-β) cytokine super family. The increased expression GDF-15 has been observed during various cardiac diseases include heart failure (HF) and may associated with worse outcomes. However, relationship still not well...
This study aimed to examine (i) whether circulating growth differentiation factor-15 (GDF-15) is associated with acute cellular cardiac allograft rejection (ACR); (ii) a longitudinal trend of GDF-15 after heart transplantation; and (iii) the prognostic value in predicting composite outcome severe primary graft dysfunction (PGD) 30 day mortality post-transplant.Serum samples were collected before transplantation at every endomyocardial biopsy (EMB) post-heart de novo transplant patients. A...
BACKGROUND Thyrotoxicosis-induced cardiomyopathy is a rare but potentially life-threatening condition that occurs in less than 1% of thyrotoxic individuals. Severely impaired left ventricular systolic function can lead to an overt cardiogenic shock requiring mechanical circulatory support. Abnormal cardiac structure and are reversible after achievement euthyroid state. CASE REPORT We present case 53-year-old patient with diagnosis thyrotoxicosis-induced acute heart failure. Transthoracic...
Cardiac complications following snake envenomation occur infrequently. Myocarditis, as a consequence of the toxic effect venom, is rare, and only few cases have been reported. We present case an 84-year-old man who was envenomed by cobra. In addition to respiratory failure due neurotoxicity cardiac abnormalities including elevated markers abnormal electrocardiogram were found. The findings on magnetic resonance imaging confirmed diagnosis acute myocarditis. patient spontaneously recovered...