A5051513331- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Asymmetric Hydrogenation and Catalysis
- Metal-Catalyzed Oxygenation Mechanisms
- Crystallography and molecular interactions
- Organophosphorus compounds synthesis
- Asymmetric Synthesis and Catalysis
- Metal complexes synthesis and properties
- Chemical Synthesis and Analysis
- Synthetic Organic Chemistry Methods
- Magnetism in coordination complexes
- Electrocatalysts for Energy Conversion
- Porphyrin and Phthalocyanine Chemistry
- Enzyme Catalysis and Immobilization
- Enzyme-mediated dye degradation
- Electrochemical sensors and biosensors
- Metalloenzymes and iron-sulfur proteins
- Lanthanide and Transition Metal Complexes
- Boron Compounds in Chemistry
- Advanced Synthetic Organic Chemistry
- Molecular spectroscopy and chirality
- Analytical Chemistry and Chromatography
- Chemical synthesis and alkaloids
- Electrochemical Analysis and Applications
- Mass Spectrometry Techniques and Applications
Institut des Sciences Moléculaires de Marseille
2009-2025
Aix-Marseille Université
2009-2025
Centre National de la Recherche Scientifique
2009-2023
Centrale Marseille
2014-2023
Institut de Chimie Radicalaire
2002
Laboratoire de Chimie de Coordination
1995-2000
Catalyse
1997
Université Paris-Sud
1996
Several recent studies have shown that the combination of photosensitizers with metalloenzymes can support a light-driven multielectron reduction molecules such as CO2 or HCN. Here we show association zinc tetramethylpyridinium porphyrin (ZnTMPyP4+) photosensitizer multicopper oxidase (MCO) laccase allows to link oxidation an organic molecule four electrons dioxygen into water. The enzyme is photoreduced within minutes porphyrin/enzyme ratio low 1:40. With 1:1 ratio, consumption rate 1.7...
In this study, two copper complexes were synthesized using N3 (arising from pyridines and one amide group) containing ligands N-(2-picolyl)picolinamide (L1H) bis(2-pyridylcarbonyl)amine (L2H), forming [(L1)CuII(OH2)(NO3)] (1) [(L2)CuII(OH2)2](NO3) (2). The reaction of complex 1 with hydrogen peroxide in alcoholic solvents yielded a formate-bound complex. Studies isotopically labeled 13C ethanol indicated that formate originates the C1 after C-C bond cleavage. Complex was found to...
Abstract Water oxidation by copper‐based complexes to form dioxygen has attracted attention in recent years, with the aim of developing efficient and cheap catalysts for chemical energy storage. In addition, high‐valent metal–oxo species produced metal presence water can be used achieve substrate oxygenation use H 2 O as an oxygen source. To date, this strategy not been reported copper complexes. Herein, a copper(II) complex, [(RPY2)Cu(OTf) ] (RPY2=N‐substituted bis[2‐pyridyl(ethylamine)]...
We describe the synthesis and characterization of a new mononuclear palladium complex ( PdL ) based on thiosemicarbazone ligand. X‐ray diffraction data collected single crystals reveal that is neutral entity with symmetric square‐planar geometry around metal center. The exhibits an electrocatalytic behavior for proton reduction in DMF solvent using trifluoroacetic acid (TFA) as source. Gas analysis under controlled conditions during 4 h at pool mercury working electrode showed moderate...
The chiral oxazaphospholidine–borane complex 2 was used as catalyst (2 mol %) in asymmetric reduction of ketones by borane with an enantioselectivity ranging from 33 to 92% at 110 °C and 100% conversion; under stoichiometric conditions the proceeded 99% enantiomeric excess.
2-Hydroxypyridine-N-oxide (HOPNO) is described as a new and efficient transition-state analog (TS-analog) inhibitor for the mushroom tyrosinase with an IC50 = 1.16 μM KI 1.8 μM. Using binuclear copper(II) complex [Cu2(BPMP)(μ−OH)](ClO4)2 (2) known functional model catecholase activity, we isolated fully characterized 1:1 (2)/OPNO adduct in which HOPNO deprotonated chelates only one Cu-atom of site bidentate mode. On basis these results, structural inhibition by proposed.
Combining a palladium-based complex with laccase allows the oxidation of an alcohol substrate at room temperature and atmospheric pressure.
We have investigated spectrally, crystallographically as well computationally charge transfer complexes involving synthesized<italic>N</italic>-aryl-<italic>N</italic>′-methyl non-symmetric viologen cations and hexacyanoferrate(<sc>ii</sc>) anions.
Abstract The synthesis of a dinuclear copper(II) complex, supported by 1,3‐diamino‐2‐propanol‐based tetraamide ligand, is reported. Structural properties in the solid state and solution, means XRD analysis NMR spectroscopy, respectively, provide evidence highly flexible complex that can display several conformations, leading to image wings butterfly. was fully characterized redox were investigated. Room‐temperature spectro‐electrochemistry used monitor formation metastable mono‐oxidized...
The chiral oxazaphospholidine (2) derived from (S)-(+)-prolinol reacts with benzyl bromide in a stereoselective Michaelis–Arbuzov reaction to give (3), an ideal precursor for the synthesis of hybrid phosphine–phosphine oxide ligand (5).
We report the synthesis and characterization of a trinuclear nickel complex. Solid state solution studies using X-ray diffraction, NMR UV-vis spectroscopy highlight square planar geometries around metal centers an all-sulfur coordination sphere. It exhibits significant electrocatalytic activity for hydrogen evolution in DMF Et3NHCl as proton source. DFT suggest that sulfur atoms act relay, proposed [NiFe] hydrogenases.
Abstract During a program dedicated to the biocatalytic access of structurally useful α‐hydroxy ketones, we made unexpected observation that epoxy enol acetates derived from (+)‐ and (–)‐menthone stereoselectively rearranged on exposure silica through diastereoselective process, providing easy complete set α‐hydroxymenthone stereoisomers. The absolute configurations four stereoisomers were unambiguously established by IR‐VCD X‐ray diffraction, thus clarifying some literature discrepancy. Two...
This study investigates the site-directed immobilization of a hybrid catalyst bearing biquinoline-based-Pd(II) complex (1) and robust laccase within cavities silica foam to favor veratryl alcohol oxidation. We performed grafting 1 at unique surface located lysine two variants, either closed (1⊂UNIK157 ) or opposite position (1⊂UNIK71 enzyme oxidation site. After into monoliths hierarchical porosity, we show that catalytic activity is dependent on orientation loading each hybrid, 1⊂UNIK157...
Abstract Polysaccharide oxidative depolymerization is highly desirable to achieve recalcitrant biomass valorization. Inspired by recently discovered Lytic Monooxygenases, mononuclear copper complexes have been prepared and studied in the literature. However, activities were evaluated on different substrates under various conditions. In this work we intended establish a robust reproducible activity assay, aqueous solution at pH close from neutrality mild We several of increasing complexity:...
Three neutral copper(II) complexes [Cu(L) 2 X] [X = none, N , ‐dimethylformamide (DMF) 0.5 ‐dimethylacetamide (DMA) for 1 and 3 respectively] containing benzotriazole–phenolate ligand HL [ 2‐(2 H ‐benzotriazol‐2‐yl)‐4,6‐di‐ tert ‐pentylphenol] have been synthesized investigated with single‐crystal X‐ray diffraction, elemental analysis, spectroscopic techniques [ESI‐MS, IR, UV/Vis, electron paramagnetic resonance (EPR)]. The geometry of complex is distorted square planar, while the...
Abstract The borane complex of (2R,4S)-2-phenyl-1,3,2- oxazaphospholidine 2 was readily synthetized. This can be used as catalyst in enantioselective reduction ketones toluene, with BH3:THF (or BH3:SMe2) reducing agent. catalytic iso-propyl methyl ketone yields (R)-3-methyl-2-butanol 92% e.e. and 100% conversion. Reduction different under stoichiometric conditions gives the corresponding alcohols = 99%.