A5076482431- Synthesis and biological activity
- Synthesis and Biological Evaluation
- Chemical synthesis and alkaloids
- Synthesis and Characterization of Heterocyclic Compounds
- Chemical Synthesis and Analysis
- Click Chemistry and Applications
- Multicomponent Synthesis of Heterocycles
- Synthesis and Catalytic Reactions
- Chemical Synthesis and Reactions
- Catalytic C–H Functionalization Methods
- Asymmetric Synthesis and Catalysis
- Sulfur-Based Synthesis Techniques
- Cancer therapeutics and mechanisms
- Meat and Animal Product Quality
- Computational Drug Discovery Methods
- Synthetic Organic Chemistry Methods
- Phenothiazines and Benzothiazines Synthesis and Activities
- Quinazolinone synthesis and applications
- Catalytic Cross-Coupling Reactions
- Cyclopropane Reaction Mechanisms
- Marine Sponges and Natural Products
- Radiopharmaceutical Chemistry and Applications
- Orthopedic Infections and Treatments
- Bioactive Compounds and Antitumor Agents
- Oxidative Organic Chemistry Reactions
Government College University, Faisalabad
2016-2025
Saarland University
2010-2020
University of Faisalabad
2020
Bahauddin Zakariya University
2011
University of Oklahoma Health Sciences Center
2003
North West London Pathology
1985
High protein content, excellent amino acid profile, absence of anti-nutritional factors (ANFs), high digestibility and good palatability fishmeal (FM), make it a major source in aquaculture. Now, FM is at risk due to an increase its demand price. So, there greatest need find cheap sources replace FM. Plant are acknowledged best their large availability low cost. However, they have certain ANFs, deficiency some acids, nutrient bioavailability poor presence starch fiber. These contrasting...
Novel azomethines derived from acefylline tethered triazole hybrids ( 7a-k ) have been synthesized and evaluated against human liver cancer cell line (Hep G2) using MTT assay. The series of exhibited promising efficacy line. Screening the identified compound 7d with least viability value (11.71 ± 0.39%) as most potent anticancer agent in contrast to reference drug (cell = 80 3.87%). In this study, potentials novel agents inhibit proteins were assessed. Subsequently, structure-activity...
Benzofuran and 1,3,4-oxadiazole are privileged versatile heterocyclic pharmacophores which display a broad spectrum of biological pharmacological therapeutic potential against wide variety diseases. This article reports in silico CADD (computer-aided drug design) molecular hybridization approaches for the evaluation chemotherapeutic efficacy 16 S-linked N-phenyl acetamide moiety containing benzofuran-1,3,4-oxadiazole scaffolds BF1-BF16. virtual screening was carried out to discover assess...
Abstract The remediation of pesticides from the environment is one most important technology nowadays. Herein, magnesium oxide (MgO) nanoparticles and calcium-doped (Ca-doped MgO) were synthesized by co-precipitation method used for degradation thiamethoxam pesticide in aqueous media. Characterization MgO Ca-doped performed XRD, SEM, EDX, FT-IR analysis to verify synthesis variations chemical composition. band gap energy crystalline size found be 4.8 4.7 eV 33 34 nm respectively. was...
ABSTRACT Microencapsulation is a methodology utilized across different areas to upgrade the viability, steadiness, and conveyance of bioactive compounds. improves stability, controlled release, sensory properties in pharmaceuticals, food products, agriculture, skincare aquaculture by enclosing molecules within protective coatings. Spray drying, emulsification, coacervation are techniques employed tailor release profiles safeguard encapsulated The microencapsulation technique shelf life...
β-Amino alcohols are versatile intermediates in the synthesis of various biologically potent compounds, which can also be achieved by ring opening epoxides amines. In present review, focus has been placed on with amines under a variety reaction parameters reported during 2011–2015. All factors that resulted excellent yields and high regioselectivity, environmentally benign, use mild conditions have discussed detail. addition, applications these methods active compounds such as β-blockers described.
Human tyrosinase (hTYR) is a key and rate-limiting enzyme along with human tyrosinase-related protein-1 (hTYRP1), which are among the most prominent targets of inhibiting hyper pigmentation melanoma skin cancer. In current in-silico computer-aided drug design (CADD) study, structure-based screening sixteen furan-1,3,4-oxadiazole tethered N-phenylacetamide structural motifs BF1-BF16 was carried out to assess their potential as hTYR hTYRP1 inhibitors. The results revealed that showed higher...
The tyrosinase enzyme has a vital role in the browning of vegetables and fruits biosynthesis melanin. In this work, we synthesized diverse library coumarin–triazole hybrids, these compounds were characterized by using suitable analytical techniques. Our research work extends beyond synthetic effort to explore therapeutic potential compounds. We put through meticulous vitro screening against enzyme, coumarin derivatives evinced good IC50 values range 0.339 ± 0.25 µM 14.06 0.92 µM. compounds,...
The urgent need to address the severe environmental risk posed by chromium-contaminated industrial wastewater necessitates development of eco-friendly cleanup methodologies. Utilizing Ficus benghalensis plant extracts, present study aims develop green zinc oxide nanoparticles for removal Cr metal ions from wastewater. leaves benghalensis, often known as banyan tree, were used extract a solution synthesizing ZnO NPs. These developed with goal efficiently eliminating chromium (Cr) effluents....
In this study, a series of 1,2,4-triazole-tethered β-hydroxy sulfide scaffolds 11a-h was synthesized in good to remarkable yields (69-90%) through the thiolysis oxiranes by thiols aqueous basic catalytic conditions. The sulfides were screened against bacterial tyrosinase enzyme, and Gram-positive Gram-negative cultures
Abstract Despite their importance to global economies, the aquaculture and seafood sectors are major contributors waste, which is a problem for environment. Because of its biocompatibility recyclability, fish rich in chitin chitosan—holds potential several fields. The shells crustaceans source chitosan, two substances with versatile useful qualities. Although it not very soluble, biocompatible biodegradable, much like cellulose. more solubilized chitosan made when deacetylated. About half...