This study presents the fabrication and characterization of mixed matrix membranes (MMMs) incorporating green-synthesized silver nanoparticles (AgNPs) using Hibiscus Rosa sinensis extract within a polyethersulfone (PES) for nanofiltration (NF) application. The were evaluated their pure water permeability, salt rejection, dye removal, antifouling performance. Results showed that membrane with 0.75 wt% AgNPs exhibited highest permeability 36 L/m2 h−1 bar−1 attributed to increased porosity...

Novel azomethines derived from acefylline tethered triazole hybrids ( 7a-k ) have been synthesized and evaluated against human liver cancer cell line (Hep G2) using MTT assay. The series of exhibited promising efficacy line. Screening the identified compound 7d with least viability value (11.71 ± 0.39%) as most potent anticancer agent in contrast to reference drug (cell = 80 3.87%). In this study, potentials novel agents inhibit proteins were assessed. Subsequently, structure-activity...

The present study was conducted to evaluate the quality of drinking water and assess potential health hazards due contaminants in selected urban areas Lahore, Pakistan. Water samples were collected from ten sites analyzed for different physico-chemical parameters including turbidity, color, pH, total dissolved solids (TDS), nitrates, fluoride, residual chlorine, hardness. Additionally, heavy metal (arsenic) microbial (E. coli) also determined samples. Drinking evaluation indices, index (WQI)...

Benzofuran and 1,3,4-oxadiazole are privileged versatile heterocyclic pharmacophores which display a broad spectrum of biological pharmacological therapeutic potential against wide variety diseases. This article reports in silico CADD (computer-aided drug design) molecular hybridization approaches for the evaluation chemotherapeutic efficacy 16 S-linked N-phenyl acetamide moiety containing benzofuran-1,3,4-oxadiazole scaffolds BF1-BF16. virtual screening was carried out to discover assess...

St. John's wort in western Europe has been extensively utilized for the treatment of mild to moderate depression. Hypericin, a red pigment, is found be responsible its antidepressant activity. The aim current study was prepare nanoemulsion (O/W) hypericin designed immediate delivery drug brain prepared by means homogenization technique, and that followed physicochemical evaluation. Tween-80, Span-80, β-cyclodextrin, ethanol, eucalyptus oil were manufacturing nanoemulsion. Morphological...

Abstract The aim of the present study was to assess drinking water quality in selected urban areas Lahore and comprehend public health status by addressing basic parameters. Total 50 tap samples were collected from groundwater two district i.e., Gulshan-e-Ravi (site 1) Samanabad 2). Water analyzed laboratory elucidate physico-chemical parameters including pH, turbidity, temperature, total dissolved solids (TDS), electrical conductivity (EC), oxygen (DO), hardness, magnesium calcium hardness....

Abstract The remediation of pesticides from the environment is one most important technology nowadays. Herein, magnesium oxide (MgO) nanoparticles and calcium-doped (Ca-doped MgO) were synthesized by co-precipitation method used for degradation thiamethoxam pesticide in aqueous media. Characterization MgO Ca-doped performed XRD, SEM, EDX, FT-IR analysis to verify synthesis variations chemical composition. band gap energy crystalline size found be 4.8 4.7 eV 33 34 nm respectively. was...

This paper aims to elucidate the effects of exogenous brassinolide (BL) on maize germination and seedling growth under chilling stress. The cold-resistant hybrid Tiannong 9 cold-sensitive Tianhe 1 were soaked at stage (6 °C) leaves sprayed (4 °C), with BL concentrations 0, 0.01, 0.1, mg/L. rate seeds changes in biomass, antioxidant, photosynthetic, plant endogenous hormone systems chloroplast ultrastructures determined. results showed that optimum concentration alleviate stress seedlings was...

Green (sustainable) chemistry provides a framework for chemists, pharmacists, medicinal chemists and chemical engineers to design processes, protocols synthetic methodologies make their contribution the broad spectrum of global sustainability. conditions, especially catalysis, are pillar green chemistry. principles help overcome problems conventional synthesis, such as slow reaction rates, unhealthy solvents catalysts long duration completion time, envision solutions by developing...

At present, the energy shortage and environmental pollution are burning global issues. For centuries, fossil fuels have been used to meet worldwide demand. However, thousands of tons greenhouse gases released into atmosphere when burned, contributing warming. Therefore, green must replace fuels, hydrogen is a prime choice. Photocatalytic water splitting (PWS) under solar irradiation could address problems. In past decade, photocatalysts manufacture sustainable fuels. Scientists working...

Human tyrosinase (hTYR) is a key and rate-limiting enzyme along with human tyrosinase-related protein-1 (hTYRP1), which are among the most prominent targets of inhibiting hyper pigmentation melanoma skin cancer. In current in-silico computer-aided drug design (CADD) study, structure-based screening sixteen furan-1,3,4-oxadiazole tethered N-phenylacetamide structural motifs BF1-BF16 was carried out to assess their potential as hTYR hTYRP1 inhibitors. The results revealed that showed higher...

Green synthesis is one of the promising pathways for biologically active nanoscale materials. Herein, an eco-friendly silver nanoparticles (SNPs) was carried out using extract Teucrium stocksianum. The biological reduction and size NPS were optimized by controlling physicochemical parameters such as concentration, temperature, pH. A comparison fresh air-dried plant extracts also undertaken to establish a reproducible methodology. biosynthesized SNPs characterized UV-Vis spectroscopy, FT-IR,...

The urgent need to address the severe environmental risk posed by chromium-contaminated industrial wastewater necessitates development of eco-friendly cleanup methodologies. Utilizing Ficus benghalensis plant extracts, present study aims develop green zinc oxide nanoparticles for removal Cr metal ions from wastewater. leaves benghalensis, often known as banyan tree, were used extract a solution synthesizing ZnO NPs. These developed with goal efficiently eliminating chromium (Cr) effluents....

In this study, a series of 1,2,4-triazole-tethered β-hydroxy sulfide scaffolds 11a-h was synthesized in good to remarkable yields (69-90%) through the thiolysis oxiranes by thiols aqueous basic catalytic conditions. The sulfides were screened against bacterial tyrosinase enzyme, and Gram-positive Gram-negative cultures

In this study 12 species of Cyperaceae have been studied for quantitative and qualitative observation pollen grains through Light scanning electron microscopy. Pollens from different wetlands Azad Jammu Kashmir were collected. Morphological characters then investigated under the Scanning microscope. Two types observed apolar heteropolar. Shape pollens was prolate (4 spp), sub-spheroidal (7 oblate (1 spp). Variation in exine sculpturing granular reticulate areolate-punctate (3 psilate (2...

Abstract Coumarin sulfonamide is a heterocyclic pharmacophore and an important structural motif which core integral part of different therapeutic scaffolds analogues. sulfonamides are privileged pivotal templates have broad spectrum applications in the fields medicine, pharmacology pharmaceutics. exhibited versatile myriad biomedical activities such as anti-bacterial, antiviral, antifungal, anti-inflammatory anti-cancer. This review article focuses on features coumarin derivatives treatment...