A5083461967- Bipolar Disorder and Treatment
- Child and Adolescent Psychosocial and Emotional Development
- Maternal Mental Health During Pregnancy and Postpartum
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Schizophrenia research and treatment
- Adolescent and Pediatric Healthcare
- Child Nutrition and Feeding Issues
- Attention Deficit Hyperactivity Disorder
- Family Support in Illness
- Treatment of Major Depression
- Family Caregiving in Mental Illness
- Child Abuse and Trauma
- Functional Brain Connectivity Studies
- Mental Health Research Topics
- Tryptophan and brain disorders
- Sleep and related disorders
- Eating Disorders and Behaviors
- Food Security and Health in Diverse Populations
- Health disparities and outcomes
- Early Childhood Education and Development
- Genetics and Neurodevelopmental Disorders
- Genetic Associations and Epidemiology
- Stuttering Research and Treatment
- Birth, Development, and Health
- Cannabis and Cannabinoid Research
Nova Scotia Health Authority
2015-2024
Dalhousie University
2015-2024
Capital District Health Authority
2014
King's College London
2011
Psychiatry Research Trust
2009
Charles University
2007
The offspring of parents with mental disorders are at increased risk for developing themselves. to may extend transdiagnostically other than those present in the parents. literature on this topic is vast but mixed. To inform targeted prevention and genetic counseling, we performed a comprehensive, PRISMA 2020-compliant meta-analysis. We systematically searched published up September 2022 retrieve original family high-risk registry studies reporting any type disorder. random-effects...
Severe mental illness (SMI), including schizophrenia, bipolar disorder and severe depression, is responsible for a substantial proportion of disability in the population. This article describes aims design research study that takes novel approach to targeted prevention SMI. It based on rationale early developmental antecedents SMI are likely be more malleable than fully developed mood or psychotic disorders low-risk interventions targeting may reduce risk Families Overcoming Risks Building...
Background Attention-deficit hyperactivity disorder (ADHD) and anxiety disorders have been proposed as precursors of bipolar disorder, but their joint relative roles in the development are unknown. Aims To test prospective relationship ADHD with onset disorder. Method We examined between ADHD, a birth cohort 2 409 236 individuals born Denmark 1955 1991. Individuals were followed from sixteenth birthday or January 1995 to first clinical contact for until December 2012. calculated incidence...
Abstract Background Social anxiety disorder increases the likelihood of unfavourable outcomes in people with bipolar disorder. Cognitive behavioural therapy (CBT) is first-line treatment for social However, have been excluded from studies that this recommendation based on. Method We completed a case series to obtain initial data on whether CBT an acceptable, safe, and effective Results Eleven euthymic participants attended up sixteen three follow-up sessions Participants average 95% offered...
Abstract Background Children of parents with mood and psychotic disorders are at elevated risk for a range behavioral emotional problems. However, as the usual reporter psychopathology in children is parent, reports early problems may be biased by parents' own experience mental illness their state. Methods Independent observers rated using Test Observation Form 378 youth between ages 4 24 (mean = 11.01, s.d . 4.40) who had parent major depressive disorder, bipolar schizophrenia, or no...
Background Attention‐deficit/hyperactivity disorder (ADHD) and lower cognitive ability have been linked with increased likelihood of exposure to adversity. We hypothesized that these associations may be partly due genetic factors. Methods calculated polygenic scores for ADHD intelligence assessed psychopathology general in a sample 297 youth aged 5–27 years enriched offspring parents mood psychotic disorders. an adversity score as mean 10 indicators, including socio‐economic disadvantage,...
Psychotic symptoms are common in children and adolescents may be early manifestations of liability to severe mental illness (SMI), including schizophrenia. SMI psychotic associated with impairment executive functions. However, previous studies have not differentiated between 'cold' 'hot' We hypothesized that the propensity for is specifically functions, such as decision-making context uncertain rewards losses.In a cohort 156 youth (mean age 12.5, range 7-24 years) enriched familial risk SMI,...
Abstract Background Offspring of parents with major mood disorders (MDDs) are at increased risk for early psychopathology. We aim to compare the rates neurodevelopmental in offspring bipolar disorder, depressive and controls. Method established a lifetime diagnosis [attention-deficit/hyperactivity disorder (ADHD), autism spectrum communication disorders, intellectual disabilities, specific learning motor disorders] using Kiddie Schedule Affective Disorders Schizophrenia, Present Lifetime...
Basic symptoms, defined as subjectively perceived disturbances in thought, perception and other essential mental processes, have been established a predictor of psychotic disorders. However, the relationship between basic symptoms family history transdiagnostic range severe illness, including major depressive disorder, bipolar disorder schizophrenia, has not examined.
Background Virtual care may improve access to healthcare and be well suited digitally connected youth, but experts caution that privacy technology barriers could perpetuate inequities. Success of virtual will depend on its alignment with patient preferences. However, information preferences for in-person is missing, especially youth. We sought quantify versus mental physical in youth their parents, including vulnerable segments the population such as families a parent severe illness (SMI)....
Abstract Background The long-term outcomes of bipolar disorder range from lasting remission to chronic course or frequent recurrences requiring admissions. distinction between I and II disorders has limited utility in outcome prediction. It is unclear what extent the clinical predicts outcomes. Methods A representative sample 191 individuals diagnosed with was recruited followed for up 5 years using a life-chart method. We previously described over first 18 months dimensional characteristics...