- Ovarian function and disorders
- Eating Disorders and Behaviors
- Reproductive Biology and Fertility
- Hormonal and reproductive studies
- Menopause: Health Impacts and Treatments
- Sexual function and dysfunction studies
- Child Nutrition and Feeding Issues
- Infant Health and Development
- Estrogen and related hormone effects
- Menstrual Health and Disorders
- Acne and Rosacea Treatments and Effects
- Sexual Differentiation and Disorders
- Reproductive Health and Contraception
- Human Health and Disease
- Women's cancer prevention and management
- Meta-analysis and systematic reviews
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Neuroendocrine regulation and behavior
- COVID-19 and healthcare impacts
- Healthcare professionals’ stress and burnout
- Growth Hormone and Insulin-like Growth Factors
- Pharmaceutical industry and healthcare
- Dermatological and Skeletal Disorders
- Botulinum Toxin and Related Neurological Disorders
- Gynecological conditions and treatments
University of Brescia
2000-2025
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
2013-2025
Brescia University
2018-2019
This study shows the effect of a long-term treatment (60 cycles) with ethinyl oestradiol/cyproterone acetate pill, and follow-up after 6 months from cessation, in polycystic ovarian syndrome. The 140 studied women had ovaries moderate or severe acne, 108 also presented hirsutism. endocrine profile significantly modified six cycles (P < 0.001), further significant decrease gonadotrophins, oestrogens androgens 12 cycles, greater increase sex hormone-binding globulins insulin-like growth...
Objective The real-world PatiEnt satisfactiON studY (PEONY) involves postmenopausal women already treated or starting local estrogen therapy (LET) ospemifene. aim of the present analysis was to assess treatment satisfaction and persistence, effectiveness patient-reported outcomes (PROs) in sexual function quality life after 6 months with LET ospemifene treat vulvovaginal atrophy (VVA).
To compare the effectiveness of finasteride and flutamide in treatment hirsutism patients with polycystic ovary syndrome (PCOS) idiopathic hirsutism. Randomized study. One hundred ten hirsute were selected: 64 women PCOS 46 Patients assigned randomly to receive 5mg once daily or 250mg twice daily, for 12 consecutive months. Hirsutism was evaluated at months therapy, Ferriman-Gallwey score measurement terminal hair diameters (microm) taken from four different body areas. Blood samples...
This study evaluated the prognosis of functional hypothalamic amenorrhea (FHA) and predictive factors recovery, through a long-term follow-up. Ninety-three women affected by FHA underwent follow-up for an average period 8.1 yr (range 7-9 yr). At end follow-up, 65 (70.7%) patients recovered. Statistical analysis showed that there was no association between recovery anamnestic causes or with echographic ovarian morphology but identified as basal body mass index (BMI), cortisol, androstenedione...
The aim of this study was to investigate whether the absence or presence acne hirsutism in 248 women with polycystic ovary syndrome associated different clinical, endocrine, metabolic and ultrasonographic factors. Patients were divided into three groups: 96 (38.7%) without any androgenic symptoms; 94 (37.9%) only hirsutism; 58 (23.4%) acne. cycle alterations (oligomenorrhea amenorrhea) echographic ovarian morphology (polycystic multifollicular ovaries) showed no significant differences...
Over the last decade, risk benefits ratio of hormone replacement therapy (HRT) has been reevaluated mainly in tens cardiovascular risk. Present Consensus Statement is largely inspired by Global on Menopausal Hormone Therapy 2013 and 2016 leading global menopause societies (The American Society for Reproductive Medicine, The Asia Pacific Menopause Federation, Endocrine Society, European Andropause International Osteoporosis Foundation North Society). aim these recommendations to provide a...
The leucine-75-proline variant of apolipoprotein A-I leads to a new hereditary systemic amyloidosis involving mostly the liver and kidney.The objective study was examine effects this on testicular structure function.This an observational in which patients with were characterized.The carried out at Endocrinology Department Brescia University.Over 13-yr period, 25 found be affected by amyloidosis. Thirteen had testicle as first or only organ involved (group 1); 12 damage followed that other...
To determinate the profile of androstenedione (A), total (T), and free testosterone (FT), dehydroepiandrosterone (DHEA), DHEA-sulphate (DHEAS), sex hormone-binding globulin (SHBG), insulin-like growth factor-I (IGF-I) IGF-binding protein-3 (IGFBP-3) in non-smoking, postmenopausal women normal weight to search for correlations between hormones carrier proteins chronological age, number years postmenopause age onset menopause.A group 149 aged 49 74 were divided into three groups based on...
Adequate counselling on contraceptive methods can help users choose the most appropriate method. The aim of this study was to assess effects structured provided by gynaecologists selection a combined hormonal contraception method.Women aged 18-40 years (n = 1871) who were considering use method (pill, transdermal patch or vaginal ring) underwent session in which comprehensive information. Pre- and post-counselling questionnaires choice completed participants.After counselling, many women (38...
Objectives This study aimed to evaluate the relation between blood pressure (BP) or heart rate and genito-urinary symptoms in 504 women across menopausal age (40–55 years old).Methods In this multicenter, cross-sectional study, data of office systolic (SBP), diastolic (DBP) were related presence vaginal dryness, dyspareunia, atrophy (VA), recurrent urinary infection (RUI), hot flushes (HF) status.Results Vaginal dryness (coefficient linear regression β = 5.45, 95% confidence interval [CI]...
In the last decade, risk benefits ratio of MHT has been evaluated mainly in terms cardiovascular risk. Present Consensus Statement is largely inspired by Global on Menopausal Hormone Therapy 2013 and 2016 leading global menopause societies (The American Society for Reproductive Medicine, The Asia Pacific Menopause Federation, Endocrine Society, European Andropause International Osteoporosis Foundation North Society).
Hirsutism in females can be a source of considerable psychological distress and threat to female identity. The aim our study was evaluate possible relationship between facial, total body hair involvement physical, mental social well-being during 12 months follow-up treatment. Both objective subjective methods evaluating hirsutism were used: the Ferriman-Gallwey (FG) scoring method questionnaires General Health Questionnaire (GHQ)-12, Polycystic Ovary Syndrome (PCOSQ) SF-12.The 469 patients...