A5074089878- Virology and Viral Diseases
- Sepsis Diagnosis and Treatment
- Chronic Kidney Disease and Diabetes
- Respiratory Support and Mechanisms
- Cystic Fibrosis Research Advances
- Global Health Care Issues
- Machine Learning in Healthcare
- Cardiac Arrest and Resuscitation
- Immune responses and vaccinations
- Hemodynamic Monitoring and Therapy
- Clinical Reasoning and Diagnostic Skills
- Sympathectomy and Hyperhidrosis Treatments
- Complement system in diseases
- Electrolyte and hormonal disorders
- Heart Rate Variability and Autonomic Control
- Mosquito-borne diseases and control
- Blood Pressure and Hypertension Studies
- Amoebic Infections and Treatments
- Malaria Research and Control
- Non-Invasive Vital Sign Monitoring
- Heme Oxygenase-1 and Carbon Monoxide
- Artificial Intelligence in Healthcare
- Migraine and Headache Studies
- Neonatal Respiratory Health Research
- Patient Safety and Medication Errors
Cambridge Health Alliance
2024
Harvard University
2022-2024
Massachusetts Institute of Technology
2022-2024
University of Maryland, Baltimore
2015-2023
Mount Auburn Hospital
2022-2023
Boston University
2023
Brigham and Women's Hospital
2022
Brown University
2018-2019
Providence College
2019
Rhode Island Hospital
2018-2019
<h3>Importance</h3> Pulse oximetry (SpO<sub>2</sub>) is routinely used for transcutaneous monitoring of blood oxygenation, but it can overestimate actual oxygenation. This more common in patients racial and ethnic minority groups. The extent to which these discrepancies are associated with variations treatment not known. <h3>Objective</h3> To determine if there disparities supplemental oxygen administration inconsistent pulse oximeter performance. <h3>Design, Setting, Participants</h3>...
A malaria vaccine based on Plasmodium falciparum apical membrane antigen 1 (AMA1) elicited strain specific efficacy in Malian children that waned the second season after vaccination despite sustained AMA1 antibody titers. With goal of identifying a humoral correlate vaccine-induced protection, pre- and post-vaccination sera from vaccinated with control group received rabies were tested for AMA1-specific immunoglobulin G (IgG) subclasses (IgG1, IgG2, IgG3, IgG4) avidity. Samples previously...
Introduction and Objectives: The Life-Space Assessment can be used to measure a patient's level of mobility. This study evaluated the relationship between life-space mobility frequency hospitalization in previous year other clinical markers health among adults with cystic fibrosis (CF). Methods: was administered ambulatory CF clinic or by telephone. Life-space correlated most recent forced expiratory volume one second as percent predicted value (FEV1 % predicted), body mass index (BMI)...
Objective. The purpose of this study was to determine whether mobility and physical activity were associated with lung function in adults cystic fibrosis (CF). Design. This a prospective cohort observational an urban, academic, specialized care center. Participants ambulatory, nonhospitalized CF. Main Outcome Measures. Mobility assessed monthly by the Life-Space Assessment (LSA) questionnaire quarterly pedometer. Lung spirometry. Results. Twenty-seven subjects participated. Subjects recorded...
Abstract Background Electronic stethoscopes are becoming more common in clinical practice. They may improve the accuracy and efficiency of pulmonary auscultation, but data to support their benefit limited. Objective To determine how auscultation with an electronic stethoscope affect decision making. Methods An online module consisting six fictional ambulatory cases was developed. Each case included a brief history lung sounds recorded analogue stethoscope. Internal medicine resident...
High resolution clinical databases from electronic health records are increasingly being used in the field of data science. Compared to traditional administrative and disease registries, these newer highly granular datasets offer several advantages, including availability detailed information for machine learning ability adjust potential confounders statistical models. The purpose this study is compare analysis same research question using an database record database. Nationwide Inpatient...
Background Correct hospital medication reconciliation is important for continuity of care, but optimal home antihypertensive ordering has not been adequately studied. Since excessive blood pressure control associated with adverse renal and cardiovascular outcomes, we assessed the association inpatient doses amlodipine (10mg vs. 5mg) length stay failure fluid electrolyte disorders (RF/FED). Methods In this retrospective cohort study, clinical demographic data on patients initially admitted to...
Abstract Background Slow correction of severe hyponatremia has been historically recommended due to the risk rare but catastrophic neurologic events with rapid correction. A recent study challenging this paradigm reported that is associated shorter hospital length stay, did not control for admission diagnosis. The objective was determine whether stay when controlling Methods This retrospective cohort based on fourth edition Medical Information Mart Intensive Care, MIMIC-IV, a deidentified,...
A 72-year-old woman presented to the emergency department with shortness of breath, diffuse swelling and a haemoglobin 4.2 g/dl. Her history was notable for an unusual necrotic occipital neck mass that had begun enlarge intermittently bleed over past year. The patient initially unable tolerate CT scan because mass, care further complicated by extended boarding more than 24 h in department. Initial fevers were attributed blood transfusion, but she subsequently developed septic shock...