Jichang Zhang

ORCID: 0000-0003-2189-0172
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About
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Research Areas
  • Esophageal Cancer Research and Treatment
  • MicroRNA in disease regulation
  • Esophageal and GI Pathology
  • Circular RNAs in diseases
  • Gastric Cancer Management and Outcomes
  • Cancer-related molecular mechanisms research
  • Tracheal and airway disorders
  • Advanced MRI Techniques and Applications
  • Cardiac Imaging and Diagnostics
  • Fuel Cells and Related Materials
  • Coronary Interventions and Diagnostics
  • Lung Cancer Diagnosis and Treatment
  • Cardiac Ischemia and Reperfusion
  • Molecular Biology Techniques and Applications
  • Cell Adhesion Molecules Research
  • Atherosclerosis and Cardiovascular Diseases
  • Metastasis and carcinoma case studies
  • Angiogenesis and VEGF in Cancer
  • Atrial Fibrillation Management and Outcomes
  • Cancer Research and Treatments
  • Medical Imaging Techniques and Applications
  • Inflammatory mediators and NSAID effects
  • Helicobacter pylori-related gastroenterology studies
  • 2D Materials and Applications
  • Cardiac pacing and defibrillation studies

Second Affiliated Hospital of Jilin University
2014-2025

Dalian University
2022-2023

Dalian University of Technology
2022-2023

University of Nottingham Ningbo China
2018-2022

Jilin University
2014-2021

Peking University
1994-2021

Peking University Cancer Hospital
1994-2021

Jilin Medical University
2020

ETH Zurich
2019

Hebei University of Technology
2016-2017

// Chun-Li Song 1 , Bin Liu Hong-Ying Diao Yong-Feng Shi Ji-Chang Zhang Yang-Xue Li Ning Yun-Peng Yu Guan Wang Jin-Peng Qian Department of Cardiology, The Second Hospital Jilin University, Changchun 130041, P. R. China Correspondence to: Song, e-mail: songchunli220@163.com Keywords: microRNA-320, cardiomyocytes, ischemia-reperfusion, hypoxia-reoxygenation, apoptosis rate Received: December 23, 2015     Accepted: April 24, 2016     Published: May 09,...

10.18632/oncotarget.9240 article EN Oncotarget 2016-05-09

The primary objective of this study investigated the role microRNA-320 (miR-320) on left ventricular remodeling in rat model myocardial ischemia-reperfusion (I/R) injury, and we intended to explore mechanism miR-320-mediated myocardium protection. We collected 120 male Wistar rats (240–280 g) then randomly divided them into three groups: (1) sham surgery group (sham group: n = 40); (2) (I/R (3) I/R with antagomir-320 + 40). Value changes heart function transesophageal echocardiography were...

10.3390/ijms151017442 article EN cc-by International Journal of Molecular Sciences 2014-09-29

Download This Paper Open PDF in Browser Add to My Library Share: Permalink Using these links will ensure access this page indefinitely Copy URL DOI

10.2139/ssrn.5091853 preprint EN 2025-01-01

The myocardial energy metabolism shift is one of the most important pathological features ischemic heart disease (IHD). Although several microRNAs (miRs) are involved in regulation metabolism, their exact effects and underlying mechanisms remain unclear. aim this study was to investigate whether microRNA(miR-210) regulates during oxidative stress H9c2 cardiomyocytes.Cell survival analyzed via CCK assay. detected by lactate assay, ATP assay RT2 profiler glucose PCR array. Protein mRNA...

10.1159/000480417 article EN cc-by-nc-nd Cellular Physiology and Biochemistry 2017-01-01

Oxidative stress induces endothelial cell apoptosis and promotes atherosclerosis development. MicroRNA‐210 (miR‐210) is linked with in different types. This study aimed to investigate the role of miR‐210 human umbilical vein cells (HUVECs) under oxidative determine underlying mechanism. HUVECs were treated concentrations hydrogen peroxide (H 2 O ), viability was evaluated using 3‐(4,5‐dimethylthiazol‐2‐yl)‐2,5‐diphenyltetrazolium bromide assay ATP assay. To evaluate H ‐mediated apoptosis,...

10.1155/2017/3565613 article EN cc-by Oxidative Medicine and Cellular Longevity 2017-01-01

Semiconductor–metal contacts as one major challenge have severely hindered the further progress of two-dimensional (2D) electronics. Here, we present a simple and effective strategy to improve electrical performances by fabricating van der Waals (vdW) heterostructures with 2D semiconductor MoS2 type-II Dirac semimetal PtTe2. The PtTe2 nanoflakes are synthesized through CVD routes separately, followed systematic material characterizations confirm their structures. Furthermore, constructed...

10.1021/acsanm.2c05051 article EN ACS Applied Nano Materials 2023-02-03

To investigate plasma total ghrelin and obestatin levels the ghrelin/obestatin ratio prospectively, in hypertensive obese patients.Height, weight, waist hip circumferences were measured normotensive patients matched healthy controls; body mass index to calculated. Fasting glucose insulin homeostasis model assessment of resistance (HOMA-IR) was determined. concentrations by radioimmunoassay calculated.A 38 patients, 40 controls enrolled. Hypertensive had lower than or controls. In addition,...

10.1177/0300060514543040 article EN Journal of International Medical Research 2014-09-03

// Chun-Li Song 1 , Bin Liu Yong-Feng Shi Ning You-You Yan Ji-Chang Zhang Xin Xue Jin-Peng Wang Zhuo Zhao Jian-Gen Yang-Xue Li Xiao-Hao Jun-Duo Wu Department of Cardiology, The Second Hospital Jilin University, Changchun 130041, Province, China Correspondence to: Song, email: singersongchunli@163.com Keywords: microRNA-130a, PTEN, PI3K/Akt/eNOS signaling pathway, coronary artery endothelial cells, cell injury Received: June 29, 2016      Accepted: September 21,...

10.18632/oncotarget.12431 article EN Oncotarget 2016-10-04

This study aimed to investigate the effect of microRNA-30b (miR-30b) in rat myocardial ischemic-reperfusion (I/R) injury model. We randomly divided Sprague-Dawley (SD) rats (n = 80) into five groups: 1) control group; 2) miR-30b 3) sham-operated 4) I/R group, and 5) I/R+miR-30b group. Real-time quantitative polymerase chain reaction, immunohistochemical staining Western blot analysis were conducted. TUNEL assay was employed for testing cardiomyocyte apoptosis. Our results showed that levels...

10.1002/jcb.25208 article EN Journal of Cellular Biochemistry 2015-04-28

Oxidative stress can induce cell injury in vascular endothelial cells, which is the initial event development of atherosclerosis. Although quantitative real-time polymerase chain reaction (qRT-PCR) has been widely used gene expression studies oxidative injuries, using carefully validated reference genes not received sufficient attention related studies. The objective this study, therefore, was to select a set stably expressed for use qRT-PCR normalization injuries human umbilical vein cells...

10.1186/s12867-017-0086-z article EN cc-by BMC Molecular Biology 2017-04-05

PURPOSE: The aim of this study was to evaluate the applicability of125 I-labeled carcinoembryonic antigen-specific monoclonal antibody CL58 in clinical radioimmunoguided surgery for colorectal cancer. METHODS: First, we tested purity and affinity constant measured binding cancer cells normal cells. Second, injected125I-labeled into nude mice with colon cancers. Then, samples from tumor, blood, tissues injected were weighed counted a gamma-ray counter assessment biodistribution. Finally,...

10.1007/bf02660772 article EN Diseases of the Colon & Rectum 2003-12-01

Sluggish oxygen reduction reaction kinetics have been a main obstacle for commercial application of fuel cells. To replace Pt-based noble metal electrocatalysts, it is crucial to develop economical materials as electrocatalysts. Herein, we provide strategy prepare Co and N codoped carbon nanotubes efficient reaction. The composites are synthesized by hydrothermal followed calcination at 900 °C. Graphitic nitride used template nitrogen source, citric acid cobalt nitrate hexahydrate sources,...

10.1039/d0na00502a article EN cc-by-nc Nanoscale Advances 2020-01-01

Introduction: Intravascular coronary stenting has been used in the treatment of artery disease (CAD), with a major limitation in-stent restenosis (ISR).The 316 stainless steel widely for stents.In this study, we developed novel coating method to reduce ISR by simultaneously vascular endothelial growth factor (VEGF) and anti-CD34 antibody on 316L steel.Methods: Round sheets D-H group were polymerized compounds generated from condensation reaction dopamine heparin using...

10.5935/1678-9741.20150016 article EN cc-by Brazilian Journal of Cardiovascular Surgery 2015-01-01

Deep hibernators go through several cycles of profound drops in body temperature during the winter season, with core temperatures sometimes reaching near freezing. Yet unlike non-hibernating mammals, they can sustain breathing rhythms. The physiological processes that make this possible are still not understood. In study, we focused on medullary Ventral Respiratory Column a facultative hibernator, Syrian hamster. Using shortened day-lengths, induced "winter-adapted" state, which is...

10.3389/fnins.2019.00376 article EN cc-by Frontiers in Neuroscience 2019-04-26
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