- Animal testing and alternatives
- Animal Behavior and Welfare Studies
- Pharmacological Effects and Assays
- Stress Responses and Cortisol
- Children's Physical and Motor Development
- Neuroendocrine regulation and behavior
- Reproductive Biology and Fertility
- Zebrafish Biomedical Research Applications
- Nerve injury and regeneration
- Cellular Mechanics and Interactions
- Mitochondrial Function and Pathology
- Neuroscience and Neuropharmacology Research
- Neurogenesis and neuroplasticity mechanisms
- Genetics and Physical Performance
- Congenital heart defects research
- Ion channel regulation and function
- Nutrition, Genetics, and Disease
- Genetic Neurodegenerative Diseases
- Neurotransmitter Receptor Influence on Behavior
Universidade de São Paulo
2024
Instituto de Biologia Molecular e Celular
2010-2020
John Wiley & Sons (United States)
2016
Ecological Society of America
2016
Universidade do Porto
2007-2009
Swedish University of Agricultural Sciences
2007
After trauma, regeneration of adult CNS axons is abortive, causing devastating neurologic deficits. Despite progress in rehabilitative care, there no effective treatment that stimulates axonal growth following injury. Using models with different regenerative capacities, followed by gain- and loss-of-function analysis, we identified profilin 1 (Pfn1) as a coordinator actin microtubules (MTs), powering regeneration. In cones, Pfn1 increased retrograde flow, MT speed, invasion filopodia MTs,...
Standard housing for laboratory mice severely restricts natural behaviour and the control that animal has over its environment. Providing cage with objects is a method been used to both increase environmental complexity, promote performance of provide greater controllability animal. This furnishing cages mostly studied in adult animals, little known about influence preweaning environment on as adults. study aimed investigate effects postweaning In this experiment, 64 pairs animals strain...
Abstract Disclosure: B.V. Azevedo: None. N. Trigueiro: J.M. Marques: V. Yariwake: L. Tamashiro: R. Cruz: M.M. Veras: Carvalho: Introduction: The Ames lineage, a mouse model with mutation in the Prop1 gene, exhibits GH, TSH, and PRL deficiencies along low levels of gonadotropins. This has prompted an investigation into aging reproductive restoration after hormone replacement reported literature. Aims: present study aims to analyze pathophysiologic mechanisms system fertility restoration....