A5026672502- Nanoplatforms for cancer theranostics
- Advanced Nanomaterials in Catalysis
- Crystallization and Solubility Studies
- Nanoparticle-Based Drug Delivery
- X-ray Diffraction in Crystallography
- Nanocluster Synthesis and Applications
- Lanthanide and Transition Metal Complexes
- Biomarkers in Disease Mechanisms
- Synthesis and biological activity
- Advanced MRI Techniques and Applications
- Nitric Oxide and Endothelin Effects
- Synthesis of Organic Compounds
- Atherosclerosis and Cardiovascular Diseases
- Healthcare Systems and Public Health
- Iron oxide chemistry and applications
- Cardiovascular Health and Risk Factors
- Hepatocellular Carcinoma Treatment and Prognosis
- Molecular Sensors and Ion Detection
- Schizophrenia research and treatment
- Synthesis and Characterization of Heterocyclic Compounds
- Cardiovascular Disease and Adiposity
- Graphene and Nanomaterials Applications
- Adipokines, Inflammation, and Metabolic Diseases
- Luminescence Properties of Advanced Materials
- Luminescence and Fluorescent Materials
Nanjing Forestry University
2024
Hefei Institutes of Physical Science
2021-2022
Chinese Academy of Sciences
2021-2022
University of Science and Technology of China
2021-2022
Binzhou University
2020-2022
Binzhou Medical University
2020-2022
Xian Yang Central Hospital
2020
Wuxi People's Hospital
2020
Hunan Institute of Mental Health
2010
Central China Normal University
2009
Peroxynitrite (ONOO–), as a short-term reactive biological oxidant, could lead to series of effects in various physiological and pathological processes due its subtle concentration changes. In vivo monitoring ONOO– relevant is urgently required. Herein, we describe novel fluorescent probe termed HBT-Fl-BnB for the ratiometric detection vitro vivo. The consists an HBT core with Fl groups at ortho para positions responding zwitterionic excited-state intramolecular proton-transfer (zwitterionic...
Herein, we developed a novel transferrin protein corona (Tpc)-modified CuGd nanoplatform (Tpc-CuGd) for tumor-targeting photothermal (PT) and chemodynamic synergistic therapy. In addition, Tpc-CuGd had an ultrahigh PT conversion efficiency (∼55.6%) excellent stability. By the calculation, Fenton-catalytic activity of was approximately 13.6 times that classical ultrasmall iron oxide, endowing strong therapy ability in tumor. Upon internalization nanoparticles (NPs), abundance Cu(II) released...
We explored the catalytic activity and magnetic resonance imaging (MRI) capacity of Cu-doped ultrasmall iron oxides with different doping ratios. Then, we screened a highly efficient active catalyst (UAC). Subsequently, biodegradable nanoliposome was developed for multimodal cancer theranostics through pH-sensitive liposome coating these UACs. Upon entering body, nanoliposomes significantly prolonged metabolic time UACs promoted their accumulation in tumors. strong photothermal (PT) effect...
The cell membrane is widely considered as a promising delivery nanocarrier due to its excellent properties. In this study, self-assembled Pseudomonas geniculate membranes were prepared with high yield drug nanocarriers, and named BMMPs. BMMPs showed biosafety, could be more efficiently internalized by cancer cells than traditional red indicating that deliver into cells. Subsequently, the coated nanoselenium (Se), subsequently loaded Mn2+ ions doxorubicin (DOX) fabricate functional...
Background: Coronary artery disease (CAD) remains the leading cause of mortality worldwide, and its susceptibility is closely associated with genetic modifications. The association between inflammation CAD has been investigated in detail. This meta-analysis was conducted based on PRISMA guidelines to evaluate tumor necrosis factor superfamily member 4 (TNFSF4) gene polymorphisms (rs3861950 T > C rs1234313 A G) risk CAD. Methods: selected criteria included 11 eligible articles...
Single-mode magnetic resonance imaging (MRI) contrast agents (CAs) in clinical settings are easily disturbed by calcification, bleeding, and adipose signals, which result inaccurate diagnoses. In this study, we developed a highly efficientT1-T2dual-mode MRI CA using an ultra-small gadolinium oxide-decorated iron oxide nanocrystal (GMIO). The element could effectively alter the properties of GMIO from soft-ferromagnetism to superparamagnetism. addition, when Gd/Fe ratio was 15% (designated as...
Objective To investigate the cognitive status of health empowerment in patients with coronary heart disease (CAD) and to analyze relationship between cognition quality life (QOL). Method s A total 86 (CHD) our hospital from January 2018 2019 were selected retrospectively by random sampling method, general demography data was collected, results Scale Empowerment (PPES) survey profile (MOS) recorded. Pearson correlation used life. Result s The score at a middle-low level...