A5102951154- Cancer-related molecular mechanisms research
- Analytical chemistry methods development
- Electrochemical Analysis and Applications
- Molecular Sensors and Ion Detection
- Luminescence and Fluorescent Materials
- Insect-Plant Interactions and Control
- Fire dynamics and safety research
- Neurobiology and Insect Physiology Research
- Neuroscience and Neuropharmacology Research
- Cancer-related gene regulation
- MicroRNA in disease regulation
- Electrochemical sensors and biosensors
- Circular RNAs in diseases
- RNA modifications and cancer
- Advanced biosensing and bioanalysis techniques
- Laser-Ablation Synthesis of Nanoparticles
- Neural dynamics and brain function
- Laser Material Processing Techniques
- Analytical Chemistry and Chromatography
- Nanoplatforms for cancer theranostics
- Intraocular Surgery and Lenses
- Corneal Surgery and Treatments
- Visual perception and processing mechanisms
- Ocular Infections and Treatments
- Corneal surgery and disorders
Nanjing Forestry University
2023-2025
Chinese Academy of Agricultural Sciences
2022-2024
Institute of Plant Protection
2022-2024
Shandong Normal University
2022-2024
Northeast Agricultural University
2024
Beijing Jishuitan Hospital
2024
Capital Medical University
2024
Peking University
2024
Hebei Medical University
2022-2024
Second Hospital of Hebei Medical University
2022-2024
Peroxynitrite (ONOO–), as a short-term reactive biological oxidant, could lead to series of effects in various physiological and pathological processes due its subtle concentration changes. In vivo monitoring ONOO– relevant is urgently required. Herein, we describe novel fluorescent probe termed HBT-Fl-BnB for the ratiometric detection vitro vivo. The consists an HBT core with Fl groups at ortho para positions responding zwitterionic excited-state intramolecular proton-transfer (zwitterionic...
// Bailing Chen 1 , Miaomiao Yu Qingshan Chang Yongju Lu Chitra Thakur Danjun Ma Zhengping Yi Fei Department of Pharmaceutical Sciences, Eugene Applebaum College Pharmacy, Wayne State University, 259 Mack Avenue, Detroit, MI, USA Correspondence: Chen, email: Keywords : mdig, H19, demethylation, prognosis Received :July 2, 2013 Accepted August 8, Published 10, Abstract Mineral dust-induced gene (mdig) had been linked to the development human lung cancers associated with environmental exposure...
Epileptic seizures or status epilepticus (SE) can cause hippocampal neuronal death, which has detrimental effects. Parthanatos, a new form of programmed cell is characterized by hyperactivation poly (ADP-ribose) polymerase-1 (PARP-1), excessive synthesis ADP-ribose polymer, mitochondrial depolarization, and nuclear translocation apoptosis-inducing factor, observed in various neurodegenerative disorders but rarely reported epilepsy. We aimed to investigate whether parthanatos participates the...
In this work, a potential-resolved electrochemiluminescence (ECL) multiplex immunoassay (MIA) was developed using zirconium-based metal–organic framework (MOF) nanoparticles with intense self-ECL as an anodic ECL tag and CdTe nanocrystals (NCs) cathodic tag. luminophore 5,5′-(anthracene-9,10-diyl)diisophthalic acid (H4ADIP) coreactant hexamethylenetetramine (HMT) bound to zirconium nodes in the MOF, giving Zr-ADIP-HMT nanoparticles. Benefiting from intrareticular charge transfer (ICT)...
The present study aimed to investigate whether ginsenoside Rb1 (G‑Rb1) attenuates spinal cord injury‑associated oxidative stress in rats by regulating the endothelial nitric oxide synthase eNOS/nuclear factor erythroid 2‑related 2 (Nrf2)/heme oxygenase (HO)‑1 signaling pathway. Sprague Dawley were randomly divided into sham operation group (S group), injury (SCI G‑Rb1 treatment (G‑Rb1 group) and SCI+G‑Rb1+Inhibitor L‑name (L‑name group). posterior limb function was evaluated via Basso,...
To assess long-term ophthalmic and clinical blood test changes in patients with different severities of diabetic retinopathy (DR). We performed a longitudinal case-control study 130 diabetes mellitus (DM) 67 controls, including visual acuities from 2,201 eye clinic visits 44,833 tests. also analyzed optic disc macular structure vasculature using optical coherence tomography (OCT) angiography (OCTA). Ninety-one percent eyes had stable acuity (better than 20/40) over 7 years. Cluster analysis...
Urban utility tunnel is a relatively independent underground closed space. This paper conducted experiments in with length of 20 m, inner diameter 1.5 m and outer 1.8 to explore the temperature distribution case fire. The formula Li's used calculate maximum rise ceiling, it found that not applicable tunnel, mainly because does consider smoke Therefore, modified, calculated result modified good agreement actual value. following conclusions are drawn:(1) roof directly above fire source...
Increased expression of mineral dust-induced gene (mdig, also named as mina53, MINA, or NO52) has been observed in a number human cancers. The mechanism how mdig contribute to the pathogenesis cancer remains be fully elucidated. In this report, we demonstrated that overexpression decreased nuclear staining signal by 4',6-diamidino-2-phenylindole (DAPI), along with considerable enhancement cell proliferation. Silencing shRNA resulted statistically significant decrease Intriguingly, reduced...
Lidocaine has been reported to induce apoptosis on rabbit corneal endothelial cells. However, the apoptotic effect and exact mechanism involved in cytotoxicity of lidocaine are not well-established human (HCE) In this study, we investigated apoptosis-inducing HCE cells vitro. After were treated with at concentrations 0.15625-10.0 g/l, morphology ultrastructure observed by inverted light microscope transmission electron (TEM). Cell viability was measured MTT assay, ratio evaluated flow...
Previous neuroimaging research has reported increased internal (neural) noise in sensory systems of autistic individuals. However, it is unclear if this difference behavioural or perceptual consequences, as previous attempts at measuring ASD psychophysically have been indirect. Here, we use a “gold standard” psychophysical double‐pass paradigm to investigate the relationship between and traits neurotypical population ( n = 43). We measured three tasks (contrast perception, facial expression...
Antineutrophil cytoplasmic antibody- (ANCA-) associated vasculitis (AAV) is characterized by small-vessel inflammation in association with autoantibodies. Balance between T follicular helper (Tfh) cells and regulatory (Tfr) critical for humoral immune responses. Accumulating evidence supports that Tfh Tfr are involved autoimmune diseases; however, their roles AAV unclear. In this study, we tested the changes of circulatory patients AAV. Twenty twenty healthy controls were enrolled. Sixteen...
Laryngeal squamous cell carcinoma (LSCC) is an aggressive and lethal malignant neoplasm with extremely poor prognoses. Accumulating evidence has indicated that preferentially expressed antigen in melanoma (PRAME) correlated several kinds of cancers. However, there little direct to substantiate the biological function PRAME LSCC. The purpose current study explore oncogenic role expression was analyzed 57 pairs LSCC tumor tissue samples through quantitative real-time PCR, correlation between...
The actin cytoskeleton forms distinct arrays which fulfil their functions during cell cycle progression. Reorganization of the occurs transition from one array to another. Although have been well described progression, dynamic organization remains be dissected.In present study, a GFP (green fluorescent protein)-mTalin (mouse talin) fusion gene was introduced into suspension-cultured tobacco BY-2 (Nicotiana tabacum L. cv Bright Yellow) cells by calli-cocultivation transformation method...