A5047393307- Global Cancer Incidence and Screening
- Cancer Risks and Factors
- Colorectal Cancer Screening and Detection
- Esophageal Cancer Research and Treatment
- Esophageal and GI Pathology
- Gastric Cancer Management and Outcomes
- Gastroesophageal reflux and treatments
- Digital Radiography and Breast Imaging
- AI in cancer detection
- Bariatric Surgery and Outcomes
- Breast Cancer Treatment Studies
- Helicobacter pylori-related gastroenterology studies
- Eosinophilic Esophagitis
- Breast Lesions and Carcinomas
- BRCA gene mutations in cancer
- Cervical Cancer and HPV Research
- Radiomics and Machine Learning in Medical Imaging
- Diet and metabolism studies
- Health disparities and outcomes
- Cardiovascular Disease and Adiposity
- Obesity and Health Practices
- Noise Effects and Management
- Body Contouring and Surgery
- Nutritional Studies and Diet
- Genital Health and Disease
University of Copenhagen
2016-2025
Copenhagen University Hospital
2010-2024
Radboud University Nijmegen
2022-2023
Gentofte Hospital
2022-2023
Radboud University Medical Center
2022-2023
Sjællands Universitetshospital, Nykøbing F.
2022
Philips (Netherlands)
2022
Karolinska Institutet
2020
Rigshospitalet
2010-2016
Region Zealand
2016
Background Developments in artificial intelligence (AI) systems to assist radiologists reading mammograms could improve breast cancer screening efficiency. Purpose To investigate whether an AI system detect normal, moderate-risk, and suspicious a sample safely reduce radiologist workload evaluate across Breast Imaging Reporting Data System (BI-RADS) densities. Materials Methods This retrospective simulation study analyzed mammographic examination data consecutively collected from January...
Abstract Background Screening mammography works better in fatty than dense breast tissue. Computerized assessment of parenchymal texture is a non-subjective method to obtain refined description tissue, potentially valuable addition density scoring for the identification women need supplementary imaging. We studied sensitivity screening by combination radiologist-assessed Breast Imaging Reporting and Data System (BI-RADS) score computer-assessed marker, resemblance (MTR), population-based...
Delivery of screening mammography differs substantially between the United States (US) and Denmark. We evaluated whether there are differences in sensitivity specificity. included screens from women screened at age 50–69 years during 1996–2008/2009 US Breast Cancer Surveillance Consortium (BCSC) ( n = 2,872,791), two population‐based programs Denmark (Copenhagen, 148,156 Funen, 275,553). Women were followed‐up for 1 year. For initial screens, recall rate was significantly higher BCSC (17.6%)...
Helicobacter pylori infection is associated with a decreased risk of esophageal adenocarcinoma, and the decreasing prevalence such might contribute to increasing incidence this tumor. We examined hypothesis that eradication treatment H increases adenocarcinoma.
There is concern about detection of ductal carcinoma in situ (DCIS) screening mammography. DCIS accounts for a substantial proportion screen-detected lesions but its effect on breast cancer mortality debated. The International Cancer Screening Network conducted comparative analysis to determine variation detection.Data were collected during 2004-2008 number examinations, detected cancers, cases and Globocan 2008 incidence rates derived from national or regional registers. We calculated...
Hormone replacement therapy (HRT) use increases breast cancer risk and mammographic density (MD). We examine whether MD mediates or modifies the association of HRT with cancer. For 4,501 participants in Danish diet, health cohort (1993–1997) who attended screening Copenhagen (1993–2001), (mixed/dense fatty) was assessed at first after entry. by questionnaire diagnoses until 2012 obtained from registry. The associations were analyzed separately using Cox's regression. Mediation analyses used...
Obesity is a risk factor for colorectal cancer. Yet, some research indicates that weight‐reducing bariatric surgery also increases cancer risk. Our study was undertaken because current evidence examining and of limited inconsistent. This population‐based cohort included adults with documented obesity diagnosis in Denmark, Finland, Iceland, Norway or Sweden 1980–2015. The incidence participants who had not undergone compared to the corresponding background population by calculating...
Obesity increases the risk of several cancers, but influence bariatric surgery on individual obesity-related cancers is unclear. This study aimed to assess impact cancer in a multi-national setting.This cohort included all adults with an obesity diagnosis identified from national patient registries Nordic countries (Denmark, Finland, Iceland, Norway and Sweden) 1980 2012. Cancer patients was compared non-operated obesity. Multivariable Cox regression provided adjusted hazard ratios (HRs) 95%...
Our objective was to use individual data on socio-demographic characteristics identify predictors of participation in mammography screening and control what extent they can explain the regional difference. We used from programmes Copenhagen, 1991-1999, Funen, 1993-2001, Denmark. Target groups were identified Population Register, came health authority, Statistics Included women eligible for at least 3 screens. The crude RR never versus always 3.21 (95%CI, 3.07-3.35) Copenhagen adjusted 2.55...
Background. Inequality in use of mammography screening across population groups is a concern since migrants are more likely to become non-users compared the general population. The aim this study was a) identify determinants participation among migrant and Danish-born women with emphasis on effect household size, socioeconomic position healthcare services, b) test whether effects were consistent non-migrant groups. Material methods. We used data from first eight invitation rounds programme...
Background: The prevalence of depression has been evaluated in populations low- and middle-income (LMI) countries but the risk not specified among persons with dementia. This cross-sectional analysis aimed to assess older people dementia living LMI countries. Methods: study analysed data from a population-based survey conducted by 10/66 Dementia Research Group 2004. Altogether, 17 031 participants eight different aged 65 years above were assessed. Logistic regression was used calculate odds...
Mammographic density is a well-established risk factor for breast cancer. We investigated the association between three different methods of measuring or parenchymal pattern/texture on digitized film-based mammograms, and examined to what extent textural features independently jointly with can improve ability identify screening women at increased The study included 121 cases 259 age- time matched controls based cohort 14,736 negative mammograms from population-based programme in Denmark 2007...
Background Recent mammography-based risk models can estimate short-term or long-term breast cancer risk, but whether assessment may improve by combining these has not been evaluated. Purpose To determine improves when a diagnostic artificial intelligence (AI) system for lesion detection and mammographic texture model. Materials Methods This retrospective study included Danish women consecutively screened at mammography from November 2012 to December 2015 who had least 5 years of follow-up...
Abstract Objective To assess the incidence rate of oesophageal adenocarcinoma among patients with non-erosive gastro-oesophageal reflux disease compared general population. Design Population based cohort study. Setting All in hospital and specialised outpatient healthcare Denmark, Finland, Sweden from 1 January 1987 to 31 December 2019. Participants 486 556 adults (>18 years) who underwent endoscopy were eligible for inclusion: 285 811 included 200 745 validation erosive disease....
Metabolic dysfunction-associated steatotic liver disease can progress to end-stage disease. Whether bariatric surgery influences this risk is uncertain. This population-based cohort study included all patients with an obesity diagnosis between 1989 and 2020 according the nationwide patient registries in Denmark, Finland, Norway, Sweden. Bariatric was compared non-operative care for incidence mortality Patients a history of alcohol overconsumption or at baseline were excluded. Multivariable...
Growing evidence suggests that air pollution may be a risk factor for breast cancer, but the biological mechanism remains unknown. High mammographic density (MD) is one of strongest predictors and biomarkers cancer risk, it has yet to linked pollution. We investigated association between long-term exposure traffic-related MD in prospective cohort women 50 years older. For 4,769 (3,930 postmenopausal) participants Danish Diet, Cancer Health (1993–1997) who attended screening Copenhagen...
Background: Attention in the 2000s on importance of mammographic density led us to study screening sensitivity, breast cancer incidence, and associations with risk factors by Danish programs. Here, we summarise our approaches findings. Methods: Dichotomized codes: fatty, equal BI-RADS code 1 part 2, other mixed/dense data from 1990s—were available two counties, codes one region were 2012/13. Density linked vital status, incident cancer, potential factors. We calculated sensitivity combining...