- Nanoparticles: synthesis and applications
- Nanoparticle-Based Drug Delivery
- Force Microscopy Techniques and Applications
- Synthetic Organic Chemistry Methods
- Cellular Mechanics and Interactions
- Graphene and Nanomaterials Applications
- Chemical Synthesis and Analysis
- Nanofabrication and Lithography Techniques
- Fluorine in Organic Chemistry
- Advanced Nanomaterials in Catalysis
- Advanced Surface Polishing Techniques
- Gold and Silver Nanoparticles Synthesis and Applications
- TiO2 Photocatalysis and Solar Cells
- Advanced biosensing and bioanalysis techniques
- Nanoplatforms for cancer theranostics
- Transition Metal Oxide Nanomaterials
- Oral microbiology and periodontitis research
- Nanomaterials for catalytic reactions
- Curcumin's Biomedical Applications
- Integrated Circuits and Semiconductor Failure Analysis
- Nanocluster Synthesis and Applications
- Clay minerals and soil interactions
- Phase Change Materials Research
- Medicinal Plant Research
- Nanotechnology research and applications
University of Salento
2016-2025
Institute for Microelectronics and Microsystems
2023-2025
National Research Council
2023-2025
Center for Biomolecular Nanotechnologies
2014
Italian Institute of Technology
2014
Radboud University Nijmegen
2003-2008
University of Bologna
2000-2003
We have studied in vitro toxicity of iron oxide nanoparticles (NPs) coated with a thin silica shell (Fe3O4/SiO2 NPs) on A549 and HeLa cells. compared bare surface passivated Fe3O4/SiO2 NPs to evaluate the effects coating particle stability toxicity. cytotoxicity was investigated by cell viability, membrane integrity, mitochondrial potential (MMP), reactive oxygen species (ROS) assays, their genotoxicity comet assay. Our results show that passivation reduces oxidative stress alteration...
In recent times, the searches for alternative materials to plastic is a popular topic, due danger that synthetic cause environment and humans. Among promising natural polymers, chitosan (CS) certainly one of most suitable since it edible, non-toxic derives from crustacean waste.- However, necessary improve its physical properties be widely applied in food packaging, whose market dominated by plastic. this work we have synthesized silver nanoparticles (AgNPs) using hot-plate microwaves-based...
The widespread use of nanoparticles (NPs) in medical devices has opened a new scenario the treatment and prevention many diseases infections owing to unique physico-chemical properties NPs. In this way, silver (AgNPs) are known have strong antimicrobial activity, even at low concentrations, due their ability selectively destroy cellular membranes. particular, field dental medicine, AgNPs different kinds prosthesis matrixes could be fundamental tool immunodepressed patients that suffer oral...
The green synthesis of nanoparticles (NPs) is currently under worldwide investigation as an eco-friendly alternative to traditional routes (NPs): the absence toxic solvents and catalysts make it suitable in design promising nanomaterials for nanomedicine applications. In this work, we used extracts collected from leaves two cultivars (Leccino Carolea) belonging species Olea Europaea, synthesize silver NPs (AgNPs) different pH conditions low temperature. underwent full morphological...
Over the last decades, several materials have been proposed for fabrication of dental and mandibular prosthetic implants. Today, poly(methyl-methacrylate) (PMMA) resin is most spread material, due to its ease processing, low cost, aesthetic properties, weight, biocompatibility, biostability in oral cavity. However, porous surface (which favors adhesion microorganisms) weak mechanical properties lead wear or fracture) are major concerns. The inclusion engineered nanomaterials acrylic matrix...
Green synthesis from plant waste involves the generation of functional nanoparticles (NPs), offering significant potential for a wide range applications. Numerous studies have focused on use extracts to produce AuNPs suitable various applications in medical field, particularly photothermal therapy and cancer therapy, owing their plasmonic properties. Moreover, NP-mediated immunostimulation immunosuppression is an intriguing field research, focusing how manipulation NP physicochemical...
Breast cancer is the most common among women, with over 1 million new cases and around 400,000 deaths annually worldwide. This makes it a significant costly global health challenge. Standard treatments like chemotherapy radiotherapy, often used after mastectomy, show varying effectiveness based on subtype. Combining these can improve outcomes, though radiotherapy faces limitations such as radiation resistance low selectivity for malignant cells. Nanotechnologies, especially metallic...
Melanoma is an aggressive cancer with rising incidence and high mortality rates, largely due to chemotherapy resistance molecular dysregulation. Nanotechnology, particularly silver nanoparticles (AgNPs), has emerged as a promising therapeutic avenue because of the nanoparticles' ability induce oxidative stress apoptosis in cells. However, conventional colloidal AgNPs lack selectivity, often causing significant damage healthy In this study, we introduce green synthesis using plant extracts,...