Zhonghua Guo

ORCID: 0000-0003-2208-1131
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Research Areas
  • Rheumatoid Arthritis Research and Therapies
  • Spinal Hematomas and Complications
  • COVID-19 and healthcare impacts
  • Bone and Joint Diseases
  • Pediatric health and respiratory diseases
  • Spine and Intervertebral Disc Pathology
  • Circular RNAs in diseases
  • Healthcare and Venom Research
  • Plant Stress Responses and Tolerance
  • Spinal Fractures and Fixation Techniques
  • Cancer-related molecular mechanisms research
  • Trauma and Emergency Care Studies
  • Aquaculture Nutrition and Growth
  • Autoimmune and Inflammatory Disorders Research
  • Plant nutrient uptake and metabolism
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • COVID-19 Clinical Research Studies
  • Traditional Chinese Medicine Studies
  • Alcohol Consumption and Health Effects
  • Heme Oxygenase-1 and Carbon Monoxide

Fujian Agriculture and Forestry University
2025

Wuhan Dongxihu District People Hospital
2018-2023

Zhengzhou City Hospital
2017

The HKT protein family plays a vital role in plant responses to salt stress by mediating sodium (Na + ) and potassium (K transport maintaining Na -K balance. Ipomoea pes-caprae ( IPC ), pantropical creeping distributed along coastal regions tropical subtropical zones, exhibits exceptional tolerance. Understanding its tolerance mechanisms provides valuable insights for developing salt-tolerant crops identifying candidate genes genetic engineering. In this study, we identified two genes,...

10.3389/fpls.2025.1538669 article EN cc-by Frontiers in Plant Science 2025-04-01

Osteoporosis (OP) is a common bone disease marked by decreased strength. Increasing evidence suggests that long non-coding RNA (lncRNAs) play important roles in the occurrence and progression of OP. This study aimed to investigate role mechanism LINC00205 osteogenic differentiation human mesenchymal stem cells (hMSCs) OP.Bone tissue samples were obtained from healthy controls patients with osteoporosis spinal fracture (OP-Frx) or without (OP-no-Frx). HMSCs cultured induced undergo...

10.1186/s12891-023-06136-z article EN cc-by BMC Musculoskeletal Disorders 2023-04-04

Numerous studies have focused on the association between heme oxygenase-1 (HO-1) gene promoter polymorphisms and susceptibility to cancer; however, results remain ambiguous. The present systematic Human Genome Epidemiology review meta-analysis aimed clarify this association. A search was used assess of HO-1 with cancer in PubMed, Web Science, Cochrane Library, Wanfang Data China National Knowledge Infrastructure databases, all reviewed published before April 10, 2017. Review Manager 5.3...

10.3892/br.2018.1048 article EN Biomedical Reports 2018-01-25

To explore the clinical effect of Sanbitang recipe in treatment for rheumatoid arthritis (RA) with kidney empty and cold-dampness symptom its safety. A total 168 cases eligible patients were randomly divided into traditional Chinese medicine (TCM) group, chemical group TCM combined 56 each group. The was treated recipe; given methotrexate tablets; And tablets adopted course 16 weeks. Health assessment questionnaire (HAQ), disease activity scores 28-joint counts (DAS28), visual analogue scale...

10.19540/j.cnki.cjcmm.20170523.004 article EN PubMed 2017-07-01

Purpose. To investigate the efficacy of percutaneous transforaminal endoscopic lumbar decompression (PTED) in treatment multisegment spinal stenosis (LSS) and its effect on VAS scores. Methods. 126 patients with LSS admitted between August 2017 2021 were selected divided into PTED group traditional open surgery (TOS group) according to different methods. There 70 cases group, treated PTED, 56 TOS surgery. The clinical outcomes, preoperative postoperative pain visual analogue scale (VAS),...

10.1155/2022/9040402 article EN Evidence-based Complementary and Alternative Medicine 2022-09-26

Objective To study the relationship between sleep disorders, pain and C-reactive protein in patients with rheumatoid arthritis. Methods A total of 115 arthritis admitted to Department Rheumatology Immunology hospital from March 2014 2016 were selected by convenient sampling. The demographics each patient recorded. Each was assessed for disorder Sleep Disorders Questionnaire (SDQ). Pain assessment performed using a simplified McGill score. At time admission, our department nurses...

10.3760/cma.j.issn.1672-7088.2019.18.005 article EN ˜The œJournal of practical nursing 2019-06-21

Abstract Background To determine an optimized treatment protocol during the COVID-19 epidemic for patients with closed fracture and delayed surgery. Methods The data of three hospitals, randomly selected from different administrative regions Wuhan, were analyzed retrospectively 23 January to 31 March 2020. Changes in number confirmed cases per day (cumulative new) each region tracked as a reflection changing risk levels. level map was drawn. status, protocols, efficiencies hospitals...

10.1186/s12891-021-04614-w article EN cc-by BMC Musculoskeletal Disorders 2021-08-30
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