Lulu Wang

ORCID: 0000-0001-9899-4493
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About
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Research Areas
  • RNA Research and Splicing
  • Plant Molecular Biology Research
  • Plant Gene Expression Analysis
  • Circular RNAs in diseases
  • Animal Virus Infections Studies
  • Plant-Microbe Interactions and Immunity
  • Virus-based gene therapy research
  • Cancer-related molecular mechanisms research
  • Photosynthetic Processes and Mechanisms
  • Pineapple and bromelain studies
  • Genomics and Phylogenetic Studies
  • RNA modifications and cancer
  • Plant tissue culture and regeneration
  • Plant Reproductive Biology
  • Plant Pathogens and Fungal Diseases
  • Epigenetics and DNA Methylation
  • Cocoa and Sweet Potato Agronomy
  • Plant Stress Responses and Tolerance
  • Plant nutrient uptake and metabolism
  • Chromosomal and Genetic Variations
  • Viral Infections and Immunology Research
  • interferon and immune responses
  • Cancer-related gene regulation
  • MicroRNA in disease regulation
  • Herpesvirus Infections and Treatments

Fujian Agriculture and Forestry University
2018-2025

Luoyang Institute of Science and Technology
2022-2025

Changchun University
2025

Southwest University
2022-2024

China Agricultural University
2020-2024

Tsinghua University
2024

First Affiliated Hospital of Nanchang University
2023-2024

Nanchang University
2023-2024

Harbin Veterinary Research Institute
2022-2024

Chinese Academy of Agricultural Sciences
2022-2024

Abstract Domestication of clonally propagated crops such as pineapple from South America was hypothesized to be a ‘one-step operation’. We sequenced the genome Ananas comosus var. bracteatus CB5 and assembled 513 Mb into 25 chromosomes with 29,412 genes. Comparison genomes CB5, F153 MD2 elucidated genomic basis fiber production, color formation, sugar accumulation fruit maturation. also resequenced 89 genomes. Cultivars ‘Smooth Cayenne’ ‘Queen’ exhibited ancient recent admixture, while...

10.1038/s41588-019-0506-8 article EN cc-by Nature Genetics 2019-09-30

With the rapid development of society and continuous progress civilization, demand for energy is greatly increasing, so researchers are eager to develop new cheap high-performance storage materials alleviate current problems. Supercapacitors (SCs) ion batteries, as mainstream chemical power supply, have unique performance advantages. SCs characteristics charge discharge storage. Ion batteries higher capacity specific capacity, output voltage, longer service life, wider environmental...

10.1016/j.ijoes.2023.100233 article EN cc-by-nc-nd International Journal of Electrochemical Science 2023-06-22

Strain BCRC 14193, isolated from soil, shared more than 99 % 16S rRNA gene sequence similarity with Bacillus amyloliquefaciens 11601T and velezensis 17467T. This strain was previously identified as B. amyloliquefaciens, based on DNA–DNA hybridization, but its DNA relatedness value 17467T 89 %. To investigate the of velezensis, partial encoding subunit B protein gyrase (gyrB) determined. high gyrB 14193 (98.4 %) all strains available (95.5–95.6 %). hybridization experiments revealed values...

10.1099/ijs.0.65191-0 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2008-03-01

Abstract Proper flower development is essential for sexual reproductive success and the setting of fruits seeds. The availability a high quality genome sequence pineapple makes it an excellent model studying fruit floral organ development. In this study, we sequenced 27 different samples integrated nine published RNA-seq datasets to generate tissue- stage-specific transcriptomic profiles. Pairwise comparisons weighted gene co-expression network analysis successfully identified ovule-,...

10.1038/s42003-020-01235-2 article EN cc-by Communications Biology 2020-09-10

Secreted RNase proteins have been reported from only a few pathogens, and relatively little is known about their biological functions. Fusarium oxysporum soilborne fungal pathogen that causes wilt, one of the most important diseases on tomato. During infection F. oxysporum, some are secreted modulate host plant immunity promote invasion. In this study, we identify an RNase, FoRnt2, secretome belongs to ribonuclease T2 family. FoRnt2 possesses N-terminal signal peptide can be oxysporum....

10.1111/mpp.13237 article EN Molecular Plant Pathology 2022-06-13

The lateral organ boundary domain (LBD) gene is a plant-specific transcription factor that plays crucial role in plant growth and development, including the development of vegetative organs such as leaf root well floral sepal, petal, pollen development. Passion fruit tropical with important agricultural, economic ornamental value. However, there no systematic research report available on LBD family passion fruit. In this study, genome-wide analysis genes identified 33 PeLBDs were unevenly...

10.3390/ijms23094700 article EN International Journal of Molecular Sciences 2022-04-24

Feline herpesvirus 1 (FHV-1) is an important pathogen causing infectious rhinotracheitis in felids, mainly infecting the upper respiratory tract and conjunctiva. Multiple vaccines are available to prevent FHV-1 infection, antibody levels always used evaluate their effectiveness. However, cellular immunity response following immunization cats remains unclear. This study investigated immune responses (humoral cellular) immunized with modified live virus vaccine. The results indicated that...

10.3389/fvets.2024.1516850 article EN cc-by Frontiers in Veterinary Science 2025-01-15

Rubus swinhoei Hance is an important plant owing to its medicinal root and edible fruit, extensively distributed in China. In this study, we reported the complete chloroplast genome of R. swinhoei. The was 156,335 bp size with overall GC content 37.15%, having a circular quadripartite structure, which contained large single-copy (LSC) small (SSC) regions 85,897 18,858 separated by pair 25,790 inverted repeat (IR) regions. comprised 131 unique genes 86 37 were protein-coding tRNA genes,...

10.1080/23802359.2025.2449690 article EN cc-by-nc Mitochondrial DNA Part B 2025-01-18

Passion fruit (Passiflora edulis), mainly distributed in tropical and subtropical regions, is popular for its unique flavor health benefits. The actin cytoskeleton plays a crucial role plant growth development, villin key regulator of dynamics. However, the mechanism underlying filament regulation reproductive development passion remains poorly understood. Here, we characterized isovariant fruit, Passiflora edulis VLN4 (PeVLN4), highly preferentially expressed pollen. Subcellular...

10.3390/ijms26052348 article EN International Journal of Molecular Sciences 2025-03-06

The HKT protein family plays a vital role in plant responses to salt stress by mediating sodium (Na + ) and potassium (K transport maintaining Na -K balance. Ipomoea pes-caprae ( IPC ), pantropical creeping distributed along coastal regions tropical subtropical zones, exhibits exceptional tolerance. Understanding its tolerance mechanisms provides valuable insights for developing salt-tolerant crops identifying candidate genes genetic engineering. In this study, we identified two genes,...

10.3389/fpls.2025.1538669 article EN cc-by Frontiers in Plant Science 2025-04-01

The secretion of peptidases from several pathogens has been reported, but the biological function these proteins in plant-pathogen interactions is poorly understood. Fusarium oxysporum, a soil-borne plant pathogenic fungus that causes wilt its host, can secrete into host cells during infection process to interfere with defense response and promote disease occurrence. In this study, we identified peptidase, FoAPY1, could be secreted F. oxysporum depending on N-terminal signal peptide protein....

10.3389/fmicb.2022.1040302 article EN cc-by Frontiers in Microbiology 2022-10-19

Abstract Biallelic mutations in the coenzyme Q7 (COQ7) encoding gene were recently identified as a genetic cause of distal hereditary motor neuropathy. Here, we explored clinical, electrophysiological, pathological, and characteristics Chinese patient with spastic paraplegia associated recessive variants COQ7 . This carried novel c.322C>A (p.Pro108Thr) homozygous variant. Sural biopsy revealed mild mixed axonal demyelinating degeneration. Immunoblotting showed significant decrease protein...

10.1002/acn3.52037 article EN cc-by-nc-nd Annals of Clinical and Translational Neurology 2024-03-04

Marek's disease (MD), an immunosuppression induced by virus (MDV), is one of the significant diseases affecting health and productive performance poultry. The roles circular RNAs (circRNAs) in MD development were poorly understood. In this study, we found a circRNA derived from exon 6 RUNX family transcription factor 2 (RUNX2) gene, named circRUNX2.2, was highly expressed chicken tumorous spleens (TS) MDV. Through fluorescence situ hybridization nuclear-cytoplasmic separation assay,...

10.1016/j.psj.2024.104045 article EN cc-by-nc-nd Poultry Science 2024-06-28

H3K4me3 and H3K36me2 histone demethylase KDM2B is an epigenetic regulatory factor involved in cell proliferation numerous cells including breast cancer cells, however, the mechanism of specifically triple negative (TNBC), remains largely unknown. In this study, we showed that higher expression level was associated with poor prognosis TNBC. Using assay, found promoted TNBC by suppressing transcription cycle inhibitors p15INK4B, p16INK4A, p57KIP2. Chromatin immunoprecipitation assay results...

10.1093/abbs/gmy084 article EN Acta Biochimica et Biophysica Sinica 2018-07-01

Strain FIRDI 006T, isolated from silage cattle feed, was characterized by using phenotypic and molecular taxonomic methods. The strain a homofermentative lactic acid bacterium; the cells stained Gram-positive were catalase-negative, non-motile, facultatively anaerobic rods. 16S rRNA gene sequence analysis revealed that belongs phylogenetically to genus Lactobacillus can be placed within acidophilus-delbrueckii group. gasseri johnsonii most closely related species, with similarities of 99.53...

10.1099/ijs.0.006783-0 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2009-07-15

Marek’s disease (MD), induced by virus (MDV), is a lymphotropic neoplastic and causes huge economic losses to the poultry industry. Non-coding RNAs (ncRNAs) play important regulatory roles in pathogenesis. To investigate host circular RNA (circRNA) microRNA (miRNA) expression profile, sequencing was performed tumourous spleens (TS), from survivors (SS) without any lesion after MDV infection, non-infected chicken (NS). A total of 2,169 circRNAs were identified more than 80% derived exon. The...

10.1080/15476286.2020.1713538 article EN RNA Biology 2020-01-17

African swine fever (ASF) is a highly contagious hemorrhagic disease of pigs, posing significant threat to the world pig industry. Several researchers are investigating possibilities for developing safe and efficient vaccine against ASF. In this regard, progress has been made some gene-deleted ASFVs reported as potential live attenuated vaccines. A seven-gene-deleted candidate HLJ/18-7GD (among which CD2v included) developed in our laboratory be protective, it expected commercialized near...

10.3390/v14081731 article EN cc-by Viruses 2022-08-06

In the Convolvulaceae family, around 1650 species belonging to 60 genera are widely distributed globally, mainly in tropical and subtropical regions of America Asia. Although a series chloroplast genomes were reported investigated, evolutionary genetic relationships among family have not been extensively elucidated till now. this study, we first complete genome sequence Ipomoea pes-caprae, coastal plant with medical values. The I. pes-caprae is 161667 bp length, GC content 37.56%....

10.3389/fpls.2022.1074697 article EN cc-by Frontiers in Plant Science 2023-01-17

Abstract SWEET transporters are a unique class of sugar that play vital roles in various developmental and physiological processes plants. While the functions SWEETs have been well established model plants such as Arabidopsis, their economically important fruit crops like pineapple not studied. Here we aimed to investigate substrate specificity by comparing protein sequences known glucose sucrose Arabidopsis with those pineapple. Our genome-wide approach 3D structure comparison showed SWEET8...

10.1093/hr/uhad175 article EN cc-by Horticulture Research 2023-04-12
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