A5070101651- Neuroinflammation and Neurodegeneration Mechanisms
- Spinal Dysraphism and Malformations
- Cancer-related molecular mechanisms research
- Plant Surface Properties and Treatments
- Immune Cell Function and Interaction
- Adenosine and Purinergic Signaling
- Plant Molecular Biology Research
- Glioma Diagnosis and Treatment
- Spinal Hematomas and Complications
- Circular RNAs in diseases
- Horticultural and Viticultural Research
- Multiple Sclerosis Research Studies
- Mathematical Biology Tumor Growth
- Plant Stress Responses and Tolerance
- Photosynthetic Processes and Mechanisms
- Spinal Fractures and Fixation Techniques
- Tryptophan and brain disorders
- MicroRNA in disease regulation
- Postharvest Quality and Shelf Life Management
- Cancer Immunotherapy and Biomarkers
- Renal Transplantation Outcomes and Treatments
Sichuan University
2024
Hebei North University
2023
Weifang People's Hospital
2020-2023
Qinghai Provincial Peoples Hospital
2022-2023
SUMMARY The cuticle is the first physical barrier covering surface of tomatoes and plays an important role in multiple stress responses. But molecular regulatory networks formation are not fully understood. In this study, we found that SlMYB72 can interact with SlTAGL1 to regulate fruit tomato. Downregulating expression inhibits cuticle, resulting a reduced thickness, accelerated postharvest water loss, increased susceptibility Botrytis cinerea . RNA sequencing analysis showed downregulation...
Ectonucleotidase CD39 hydrolyzing extracellular ATP (eATP) functions as a key modulator of immune response in the tumor microenvironment, yet role contributing stem cells more immunosuppressive microenvironment remains elusive. Here we report that upregulation is crucial for decrease concentration around glioma (GSCs) to maintain an microenvironment. Adriamycin (ADM) able promote release ATP, which recruits dendritic (DCs) phagocytose GSCs. inhibition further increased concentrations...
Cell division cycle 42 (CDC42) regulates T helper (Th) cell differentiation and is related to psychological disorders. This study aimed assess the correlation between blood CDC42 Th cells, their association with mental issues in stroke patients. Peripheral samples were obtained from 264 patients 50 controls. Then, serum was measured by enzyme-linked immunosorbent assay, Th1, Th2, Th17 cells detected flow cytometry. Hospital Anxiety Depression Scale (HADS) Mini Mental State Examination (MMSE)...
Abstract: Emerging evidence has demonstrated that long noncoding RNAs are related to the pathogenesis of atherosclerosis. We aimed investigate roles and molecular mechanisms myocardial infarction–associated transcript (MIAT) in proliferation, migration, invasion oxidized low-density lipoprotein (ox-LDL)-induced vascular smooth muscle cells (VSMCs). Quantitative real-time polymerase chain reaction was conducted determine levels MIAT, microRNA490-3p (miR-490-3p), intercellular adhesion...
The heterogeneity of glioblastoma can suppress immune cell function and lead to evasion, which presents a challenge in developing effective molecular therapies for tumor cells. However, the study holds great potential clinical immunotherapy. Liquid biopsy is useful tool accurately monitoring dynamic changes microenvironment. This paper explores microenvironment, providing therapeutic basis individualized treatment. Using liquid technology as new diagnostic method, innovative treatment...