Silica is the second most common element after oxygen, and therefore, exposures to crystalline silica dust occur in a large variety of occupations such as metal foundries, constructions, ceramic, quarry, pottery industries. Since exposure has been linked with silicosis, lung cancer, other pulmonary diseases, adverse effect attributed this be cause for concern worldwide. workers still considered important health problem especially developing countries. The aim study was investigate effects...

The main goal of this study was to investigate the effect exposure time and smoking habit on arsenic levels in biological samples workers occupationally exposed metals comparison with non-occupational residents Turkey.Blood, urine hair were collected from 95 metal at Ankara Occupational Diseases Hospital, Turkey.Similarly, 94 taken controls.Arsenic measured using Graphite Furnace Atomic Absorption Spectrometry (GFAAS) equipped Zeeman background correction Hydride Generation (HGAAS).In...

Arsenic (As) exposure may cause several medical problems. There were a few studies investigated whether it has affected bone tissue in women. However, there was no study men. The aim of this to evaluate associations between mineral density (BMD) and As men subjects.We enrolled 254 subjects who due chronic suspected 82 as control group. Hair levels detected by hair analysis (Varian AA240Z Zeeman Atomic Absorption Spectrometer, USA). BMD measurements obtained using dual-energy X-ray...

Abstract Workers in denim sandblasting are at a high risk of developing silicosis, an occupational lung disease caused by inhaling crystalline silica dust. The development and progress silicosis is associated with the activation immune system oxidative stress. In former, interferon-gamma induces both neopterin release enzyme indoleamine [2, 3]-dioxygenase (IDO) various cells. determination kynurenine-to-tryptophan ratio concentration has proven to be efficient method monitor status IDO...

Objective: Lead exposure linked to osteoporosis in women. However, there is no direct evidence whether lead has effects on bone metabolism middle-aged male subjects. Therefore, the present study investigated relationship between mineral densitometry measurements, markers, endocrine hormones and blood levels.Material methods: The included patients (n: 30) control subjects 32). We recorded information patient demographics risk factors of osteoporosis. Blood levels were evaluated using Varian...

Objective. Acute mercury intoxication among children can occur through unintentional exposure, and neurotoxicity is one of the main findings in acute exposures. In this study, we aimed to study central nerve system markers, namely neuron-specific enolase (NSE), S100B, glutamate receptor (GRIA 1) levels discuss mechanisms damage whether these parameters could be used as markers elemental neurotoxicity. Materials methods. This a case-control which includes 169 with intoxication, who were...

The aim of this study was to investigate the association between DNA damage and blood lead levels in individuals occupationally exposed lead. To evaluate association, 61 workers were monitored terms lymphocytes. measured according 3 comet assay parameters, including tail intensity (TI), moment (TM), (DNAt). A statistically significant positive correlation found TI, TM, DNAt (p <.01). Smoking had independent effects on damage. difference observed smokers nonsmokers regards parameters <.05)....

It is known that ceramic workers are potentially exposed to complex mixture of chemicals such as silica, inorganic lead, lime, beryllium and aluminum can be associated with an increased risk several diseases. All operations in the industries mixing, moulding, casting, shaking out finishing jobs, have been higher exposure levels most silica-related industries, average overall exceeded permissible for respirable crystalline silica. The aim this study was evaluate possible genotoxic damage...

AbstractAsphalt has a highly complex structure and it contains several organic compounds including polycyclic aromatic hydrocarbons heterocyclic compounds. In this study, comet assay was used to detect the DNA damage in blood lymphocytes of 30 workers exposed asphalt fumes nonexposed controls. This is first report on Turkish workers' investigated using alkaline single cell gel electrophoresis (SCGE). The evaluated by percentage tail (% DNA) for each cell. According our results, had higher...

Background: To evaluate electrocardiographic parameters which are related with atrial and ventricular arrhythmias measured from 12-lead surface electrocardiogram (ECG) in workers occupationally exposed to lead.Methods: Sixty lead-exposed 60 healthy controls were enrolled.Twelve-lead ECG was recorded measurements of P wave durations (Pmax, Pmin) dispersion (PWD), QT (QTd), corrected (QTc), Tp-e interval, Tp-e/QT ratio analyzed.Results: The control groups similar respect baseline demographic,...

Long-term organic solvent exposure may cause toxic effects in central nervous system . Trichloroethylene (TCE) is known to be one of the neurotoxic chlorinated solvents. Trichloroacetic acid (TCA) an oxidative pathway metabolite TCE. S100B, a calcium-binding protein glial cells, and neuron specific enolase (NSE) cytoplasma are markers astrocyte damage, respectively.Clinical laboratory assesments were performed 25 participants with history. Control group included healthy age sex-matched...

Purpose:To investigate the current status of exposure to mercury (Hg) among dental health workers in Turkey. Methods:A total 115 persons working same hospital were included study and divided into three groups. Group 1 consisted 67 dentists; group 2 21 personnel who work with amalgam, 3 27 control subjects but are non-dental personnel. The number amalgam fillings that have been made by dentists own recorded. Results:Plasma Hg levels found be 3.76 ± 1.84, 3.54 1.83, 2.69 0.97 µg/L groups 1, 2,...

The aim of this study was to determine 8-hydroxydeoxyguanosine (8-OH-dG) levels in trichloroethylene (TCE)-exposed workers. Oxidative stress biomarkers and biochemical parameters were monitored among 26 TCE-exposed workers 78 age-matched control subjects. Levels urinary 8-OH-dG analyzed by liquid chromatography tandem mass spectrometry. Urinary significantly higher for group (p < .001). Spearman's correlation test revealed positive correlations between trichloroacetic acid age, 8-OH-dG,...

&lt;b&gt;&lt;i&gt;Objective:&lt;/i&gt;&lt;/b&gt; The aim of this study was to assess exercise heart rate recovery (HRR) indices in mercury-exposed individuals when evaluating their cardiac autonomic function. &lt;b&gt;&lt;i&gt;Subjects and Methods:&lt;/i&gt;&lt;/b&gt; Twenty-eight 28 healthy controls were enrolled. All the subjects underwent testing transthoracic echocardiography. HRR calculated by subtracting first- (HRR1), second- (HRR2) third-minute (HRR3) rates from maximal rate. two...

Arterial hypertension is one of the physical complications chronic lead exposure. Hypertension has effects on aortic elastic properties. The aim this study was to evaluate properties in workers occupationally exposed lead. Forty-one who were and 39 healthy controls included study. All patients underwent transthoracic echocardiography for detecting parameters. There no differences baseline characteristics between lead-exposure group controls. Aortic strain (9.4% ± 4.5% vs 12.4% 4.2%, P =...

The purpose of the study was to evaluate bone mineral density (BMD) and 25-hydroxyvitamin D (25(OH)D) levels in patients with silica exposure.The included 104 male subjects exposure 36 healthy subjects. Posterior-anterior radiographs were classified according International Labour Office (ILO) Classification. Category 0 as Group I (n = 54), category II 25), III 25).Femoral neck BMD values significantly lower (p 0.007). Lumbar vertebrae all groups than control group 0.000). osteoporosis rate...

Abstract Objectives Occupational lead (Pb) exposure is still an important health problem in the world. Long-term Pb causes several adverse effects. The aim of this study was to investigate changes inflammation markers with chronic by analyzing neopterin levels and kynurenine (Kyn) tryptophan (Trp) ratio that reflects indolamine 2,3-dioxygenase activity compare healthy volunteers’ parameters. Methods Blood (BLLs) were analyzed atomic absorption spectrometry. Urinary serum Kyn Trp...

Di(2-ethylhexyl)phthalate (DEHP) is the most widely used phthalate. DEHP highly in PVC floorings and windows carpeting. The objective of this study was to determine sex hormone levels, oxidative stress parameters, selenium DNA damage, phthalate levels plastics workers (n = 24, age 20-58 years) working production rubber mechanical goods exposed workplace. control group 29, 25-54, all male) selected from age-matched healthy adults. Antioxidant parameters damage were determined by...