- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Plant Toxicity and Pharmacological Properties
- Phytochemicals and Antioxidant Activities
- Magnolia and Illicium research
- Iron Metabolism and Disorders
- Sesquiterpenes and Asteraceae Studies
- Insect Resistance and Genetics
- Plant Molecular Biology Research
- GABA and Rice Research
- Plant Stress Responses and Tolerance
- Neurobiology and Insect Physiology Research
- Seed Germination and Physiology
- Pharmacological Effects of Natural Compounds
- Catalytic C–H Functionalization Methods
- Catalytic Cross-Coupling Reactions
- Photosynthetic Processes and Mechanisms
- Plant Gene Expression Analysis
- Essential Oils and Antimicrobial Activity
- Geological and Geochemical Analysis
- Geochemistry and Geologic Mapping
- Insect and Arachnid Ecology and Behavior
- Fungal Biology and Applications
- Traditional and Medicinal Uses of Annonaceae
- CRISPR and Genetic Engineering
Minzu University of China
2015-2025
State Ethnic Affairs Commission
2021-2025
Ministry of Education
2024
North Shore Diabetes and Endocrine Associates
2024
Nantong University
2024
Tata Institute for Genetics and Society
2024
University of California, Los Angeles
2024
Hubei University of Automotive Technology
2024
Southeast University
2023-2024
Jianghan University
2023
Plants exhibit reduced root growth when exposed to low temperature; however, how temperature modulates remains be understood. Our study demonstrated that reduces both meristem size and cell number, repressing the division potential of meristematic cells by reducing auxin accumulation, possibly through repressed expression PIN1/3/7 biosynthesis-related genes, although experiments with exogenous application also suggest involvement other factor(s). In addition, we verified ARABIDOPSIS RESPONSE...
Nitric oxide (NO) has been shown to play an important role in the plant response biotic and abiotic stresses Arabidopsis mutants with lower or higher levels of endogenous NO. The exogenous application NO donors scavengers also suggested for defense against environmental stress. In this study, rice plants under drought high salinity conditions showed increased nitric synthase (NOS) activity levels. Overexpression rat neuronal (nNOS) both NOS accumulation, resulting improved tolerance...
Grain size is one of the most important factors affecting rice grain quality and yield, attracts great attention from molecular biologists breeders. In this study, we engineered a CRISPR/Cas9 system targeting miR396 recognition site GS2 gene, which encodes growth-regulating factor 4 (OsGRF4) regulates multiple agronomic traits including size, quality, nitrogen use efficiency, abiotic stress response, seed shattering. contrast to previous genome editing efforts in indel mutations were chosen...
Among super-resolution microscopy techniques, structured illumination (SIM) shows great advances of low phototoxicity, high speed, and excellent performance in long-term dynamic observation, making it especially suitable for live cell imaging. This review delves into the principles, instrumentation, applications SIM, highlighting its capabilities achieving spatiotemporal resolution. Two types mechanics are employed: (1) stripe-based where stripes formed through interference or projection,...
The human telomeric repeat CCCTAA has been reported to form a higher-order structure called an intercalated motif (i-motif) that plays important roles in telomere function and telomerase activity regulation, small molecule ligands targeting i-motif (hTelo-iM) is promising therapeutic strategy for cancer treatment, yet the folding pattern of long repeats hTelo-iM ligand screening have not studied extensively. In this study, we systematically investigated structures formed by four eight C-rich...
The Zhengchong gold deposit is located in the central segment of Jiangnan Orogen northeastern Hunan Province, South China. host rocks this are Neoproterozoic slates Lengjiaxi Group and granodiorite. structures dominated by NE-trending reverse faults, which control gold-bearing veins. orebody consists laminated quartz veins NW-trending alteration styles include silicification, carbonatization, sulfidation, sericitization chloritization. mineralization can be divided into four stages:...
Stem cell niche is critical for regulating the behavior of stem cells. Drosophila neural cells (Neuroblasts, NBs) are encased by glial closely, but it still remains unclear whether can regulate self-renewal and differentiation NBs. Here, we show that ferritin produced glia, cooperates with Zip13 to transport iron into NBs energy production, which essential proliferation The knockdown encoding genes causes shortage in via downregulating aconitase activity NAD + level, leads low premature...
MicroRNA (miR)-92 expression is often aberrant in human cancers. However, its gastric carcinoma and relation to clinicopathological features prognosis are unclear. Tissue microarrays were constructed from 180 patients with cancer (GC), who undergoing radical resection. MiR-92a was detected using miRNA-locked nucleic acid situ hybridization, correlation overall survival analyzed. decreased 13.9 % (25/180) of GC, increased 81.1 (146/180), unchanged 5.0 (9/180), compared paracancerous normal...
In this letter, we successfully explored a cascade Pd/Cu-catalyzed intermolecular C(sp3)-H arylation of amides and intramolecular C-N coupling reaction. This method provides one-pot strategy to synthesize 3,4-2 H-quinolinone with good regioselectivity C-H from C-I C-X bonds readily available starting materials.
The objective of our study is to find out the relationship between intangible assets and financial performance listed technology firms in Hong Kong exchange market. Through reviewing firms' annual reports for a five year period (from 2008 2012), we have collected data three kinds assets, which are research development cost, employee benefit expense, sales training. Meanwhile, used total net profit as control variables analyzing performance, represented by return on (ROA) firms. Using lagged...
Jasmonic acid (JA) signaling plays a pivotal role in plant development and defense. MYC2 is master transcription factor JA signaling, was found to be phosphorylated negatively regulated by MAP kinase receptor-like kinase. However, the kinases that positively regulate through phosphorylation promote MYC2-mediated activation of response have not been identified. Here, we identified CK2 as phosphorylates thus regulates signaling. holoenzyme can interact with using its regulatory subunits...
G-quadruplexes can bind with hemin to form peroxidase-like DNAzymes that are widely used in the design of biosensors. However, catalytic activity G-quadruplex/hemin DNAzyme is relatively low compared natural peroxidase, which hampers its sensitivity and, thus, application detection nucleic acids. In this study, we developed a high-sensitivity biosensor targeting norovirus acids through rationally introducing dimeric G-quadruplex structure into DNAzyme. strategy, two separate molecular...
The basic/helix-loop-helix (bHLH) transcription factors are ubiquitous transcriptional regulators that control many different developmental and physiological processes in the eukaryotic kingdom. In this study, function of AtbHLH112, an uncharacterised member bHLH family Arabidopsis was investigated. Overexpression AtbHLH112 suppressed lateral root (LR) development seedlings. Examination under microscope revealed abnormal primordia (LRP) with flat-head more than four cell layers retained...