A5016692321- Insect Resistance and Genetics
- Iron Metabolism and Disorders
- Neurobiology and Insect Physiology Research
- Insect and Arachnid Ecology and Behavior
- Renal and related cancers
- vaccines and immunoinformatics approaches
- Animal Virus Infections Studies
- Genetics, Aging, and Longevity in Model Organisms
- Studies on Chitinases and Chitosanases
- Transgenic Plants and Applications
- Bacteriophages and microbial interactions
- Poxvirus research and outbreaks
- Cancer-related gene regulation
- Microbial infections and disease research
Ministry of Education
2024
Nantong University
2024
Tata Institute for Genetics and Society
2024
University of California, Los Angeles
2024
Southeast University
2023-2024
Harbin Veterinary Research Institute
2024
Chinese Academy of Agricultural Sciences
2024
Smallpox is a highly contagious human disease caused by the variola virus. Although was eliminated in 1979 due to its nature and historical pathogenicity, with mortality rate of up 30%, this virus an important candidate for biological weapons. Currently, vaccines are critical measures prevent infection spread. In study, we designed peptide vaccine using immunoinformatics tools, which have potential activate immunity against efficiently. The design peptides derives from vaccine-candidate...
Stem cell niche is critical for regulating the behavior of stem cells. Drosophila neural cells (Neuroblasts, NBs) are encased by glial closely, but it still remains unclear whether can regulate self-renewal and differentiation NBs. Here, we show that ferritin produced glia, cooperates with Zip13 to transport iron into NBs energy production, which essential proliferation The knockdown encoding genes causes shortage in via downregulating aconitase activity NAD + level, leads low premature...
Abstract For the development of a competitive ELISA (cELISA) to detect serum antibodies against Mycoplasma mycoides subsp. Mycoides ( Mmm ) (strain PG1), causative agent contagious bovine pleuropneumonia (CBPP), all proteins this pathogen were analyzed. Then, specific extracellular region transmembrane protein with potential for diagnosis was identified. After that, monoclonal antibody (Mab) named 3A8 obtained using as an immunogen. Finally, cELISA established domain coating antigen, Mab...
Stem cell niche is critical for regulating the behavior of stem cells. Drosophila neural cells (Neuroblasts, NBs) are encased by glial closely, but it still remains unclear whether can regulate self-renewal and differentiation NBs. Here we show that ferritin produced glia, cooperates with Zip13 to transport iron into NBs energy production, which essential proliferation The knockdown encoding genes causes shortage in NBs, leads low premature Moreover, level production affected status...
Stem cell niche is critical for regulating the behavior of stem cells. Drosophila neural cells (Neuroblasts, NBs) are encased by glial closely, but it still remains unclear whether can regulate self-renewal and differentiation NBs. Here we show that ferritin produced glia, cooperates with Zip13 to transport iron into NBs energy production, which essential proliferation The knockdown encoding genes causes shortage in via downregulating aconitase activity NAD + level, leads low premature...
Stem cell niche is critical for regulating the behavior of stem cells. Drosophila neural cells (Neuroblasts, NBs) are encased by glial closely, but it still remains unclear whether can regulate self-renewal and differentiation NBs. Here, we show that ferritin produced glia, cooperates with Zip13 to transport iron into NBs energy production, which essential proliferation The knockdown encoding genes causes shortage in via downregulating aconitase activity NAD + level, leads low premature...
Stem cells are heterogeneous to generate diverse differentiated cell types required for organogenesis; however, the underlying mechanisms that differently maintain these stem not well understood. In this study, we identify Golgi-to-endoplasmic reticulum (ER) retrograde transport specifically maintains type II neuroblasts (NBs) through Notch signaling. We reveal intermediate neural progenitors (INPs), immediate daughter of NBs, provide Delta and function as NB niche. The used by INPs is...
Abstract Stem cell niche is critical for regulating the behavior of stem cells. Drosophila neural cells (Neuroblasts, NBs) are encased by glial closely, but it still remains unclear whether can regulate self-renewal and differentiation NBs. Here we show that ferritin produced glia, cooperates with Zip13 to transport iron into NBs energy production, which essential proliferation The knockdown encoding genes causes shortage in via downregulating aconitase activity NAD + level, leads low...