A5073469661- Hemodynamic Monitoring and Therapy
- Sepsis Diagnosis and Treatment
- Renal function and acid-base balance
- Heart Rate Variability and Autonomic Control
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiovascular and exercise physiology
- Heart Failure Treatment and Management
- Health and Medical Research Impacts
- Blood Pressure and Hypertension Studies
<h3>Importance</h3> Vasopressors are commonly administered to intensive care unit (ICU) patients raise blood pressure. Balancing risks and benefits of vasopressors is a challenge, particularly in older patients. <h3>Objective</h3> To determine whether reducing exposure through permissive hypotension (mean arterial pressure [MAP] target, 60-65 mm Hg) reduces mortality at 90 days ICU aged 65 years or with vasodilatory hypotension. <h3>Design, Setting, Participants</h3> A multicenter,...
The dose requirements and duration of effect transdermal nitroglycerin in patients with heart failure are not clearly established. In a first series eight chronic we gave incremental doses until pulmonary capillary wedge pressure fell at least 30% within 4 hr three consecutive patients. Thus found that single 60 mg/24 (120 cm2) was the minimal effective dose. Transdermal or placebo then given as application random double-blind fashion to 15 additional (eight received seven placebo),...
Vasodilatory shock is common in critically ill patients and vasopressors are a mainstay of therapy. A meta-analysis suggested that use higher, as opposed to lower, mean arterial pressure target guide titration vasopressor therapy, could be associated with higher risk death older patients. The 65 trial pragmatic, multi-centre, parallel-group, open-label, randomised clinical permissive hypotension (a 60 -65 mmHg during therapy) versus usual care aged years or over vasodilatory hypotension....
Vasodilatory shock is common in critically ill patients and vasopressors are a mainstay of therapy. A meta-analysis suggested that use higher, as opposed to lower, mean arterial pressure target guide titration vasopressor therapy, could be associated with higher risk death older patients. The 65 trial pragmatic, multi-centre, parallel-group, open-label, randomised clinical permissive hypotension (a 60–65 mmHg during therapy) versus usual care aged years or over vasodilatory hypotension....