A5091517522- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Essential Oils and Antimicrobial Activity
- Phytochemical compounds biological activities
- Traditional and Medicinal Uses of Annonaceae
- Phytochemistry and Bioactive Compounds
- Sesquiterpenes and Asteraceae Studies
- Phytochemistry and Bioactivity Studies
- Plant Toxicity and Pharmacological Properties
- Advances in Cucurbitaceae Research
- Genetic Mapping and Diversity in Plants and Animals
- Phytochemical and Pharmacological Studies
- Plant-derived Lignans Synthesis and Bioactivity
- Phytochemicals and Antioxidant Activities
- Biological Activity of Diterpenoids and Biflavonoids
- Seed and Plant Biochemistry
- Peroxisome Proliferator-Activated Receptors
- Energy Load and Power Forecasting
- Plant-based Medicinal Research
- Lipid metabolism and biosynthesis
- Synthesis and biological activity
- Dye analysis and toxicity
- Phytochemical Studies and Bioactivities
- Ginger and Zingiberaceae research
- Ethnobotanical and Medicinal Plants Studies
Hanoi University of Pharmacy
2025
Vietnam Academy of Science and Technology
2019-2024
Thuongmai University
2024
Hanoi University of Science and Technology
2019-2023
Ministry of Public Security of the People's Republic of China
2023
National University of Singapore
2007
TLC-SERS analysis of PDE-5 inhibitors adulterated in herbal products.
Phytochemical investigation and chromatographic separation of extracts from the aerial parts Dianella ensifolia (L.) DC. (synonym nemorosa Lam. Ex. Schiler f.) led to isolation 10 compounds, structures which were determined by HR-ESI-MS 1 D- 2 D-NMR spectroscopies, comparisons with published studies. Among isolated compounds three flavans, a biflavan, biflavone, tetralone, naphthalen glycoside, an aromatic compound, two steroids. Six these known chemicals, while identified as new compounds:...
Abstract A phytochemical study of the ethyl acetate extract (EtOAc) Peltophorum pterocarpum stems, collecting from Ha Noi city, Vietnam, has resulted in isolation and determination six compounds, including bergenin ( 1 ), cinchonain Ia 2 lupeol 3 betulinic acid 4 gallic 5 pyrogallic 6 ). The chemical structures these compounds were characterized by NMR‐spectra, MS data. Compounds found genus for first time.
In previous studies, we isolated the known compound saponin XII from roots of Dipsacus japonicus Miq. Here, show that this reduced number acute myeloid leukemia OCI-AML3 cells as evaluated by a hemocytometer. Flow cytometry analyses demonstrated reported activity was associated with significant increase apoptosis and in G0/G1 phase cell cycle, decrease S G2/M phases. Thus, inhibition growth due to antiproliferative pro-apoptotic effects. Interestingly, bioactivity exerted its effect at...
Phytochemical investigation of methanol extract from Elaeocarpus hainanensis Oliv. leaves and twigs led to the isolation structural determination three 16,23-epoxycucurbitacin-type triterpenoids, including a new hydroperoxide, 16α,23α-epoxy-3β,20β-dihydroxy-24α-hydroperoxy-10αH,23βH-cucurbit-5,25-dien-11-one (elahainencin A, 1), two known analogs (2 3). Their chemical structures were determined by spectroscopic analyses, 1 D-, 2 D NMR HR ESI MS spectra. Compound represents cucurbitacin...
Three sesquiterpene lactones (1-3) were isolated from the aerial part of Tithonia diversifolia (Hemsl.) A. Gray grown in Hoa Binh province Viet Nam. The structures these three identified as tagitinin A (1), 1β-hydroxytirotundin 3-O-methyl ether (2), and C (3) by analyzing spectroscopic data. For first time, compound 2 was T. growing Furthermore, contrary to existing literature, we determined that 1 major isolate. Compounds 3 significantly decreased numbers acute myeloid leukemia OCI-AML3...
Abstract Eight sesquiterpenoids including costunolide (1) , parthenolide (2) 11 α ,13‐dihydroparthenolide (3) 9 β ‐hydroxy‐dihydroparthenolide (4) (‐)‐bisparthenolidine (5) ,13‐dihydro‐ ‐cyclocostunolide (6) ‐cadinol (7) magnograndiolide (8) were isolated from the barks and roots of Michelia alba . The structures these compounds elucidated by spectroscopic methods (MS, 1D 2D NMR) comparison with reported data. Compounds 5 ‐ 8 have been for first time alba.
AbstractThe phytochemical investigation of Gnetum latifolium var. funiculare Markgr. resulted in the isolation five compounds (1-5). Their structures were determined as bisisorhapotingenin A (1), genetifolin E (2), K (3), piceid (4), and isorhapontin (5) based on extensive analyses HR-ESI-MS, 1D 2D NMR spectra. All these isolated evaluated for their inhibition effect lipopolysaccharide (LPS)- induced nitric oxide (NO) production RAW264.7 macrophages. Among them, two (1 3) showed moderate NO...
Phytochemical study of the leaves
Vietnam's economy has experienced complicated and unpredictable inflationary periods such as 1986. Therefore, the research to forecast inflation is significant in both macro micro aspects. It not only contributes improving efficiency ofpolicy administration, but it also used towards goal of stability, sustainability economic growth, competitiveness enterprises economy. There are many quantitative studies on forecasting world Vietnam, notably using SVAR multivariate models. This paper will...
The expression of the oncogene zinc-finger protein 217 (ZNF217) has been reported to play a central role in cancer development, resistance, and recurrence. Therefore, targeting ZNF217 proposed as possible strategy fight cancer, making necessary discover novel com-pounds. present work aims characterize chemopreventive properties cucurbitacin D , compound with broad range anticancer effectsin relation expression. Different cucurbitacins were isolated from Vietnamese plant Elaeocarpus...
Đặt vấn đề: Tinh dầu Húng quế (Ocimum basilicum L.) đã được chứng minh có tác dụng kháng viêm. Tuy nhiên, chưa nghiên cứu về này của cao toàn phần từ quế. Mục tiêu: Xác định hàm lượng polyphenol tổng, flavonoid phần, thành tinh và viêm các chiết ethanol 45%, 96% lá Đối tượng phương pháp: Định trong bằng pháp Folin-Ciocalteu tạo màu với AlCl3, tương ứng. Phân tích GC-MS. Mô hình gây bàn chân chuột carrageenan áp để khảo sát dầu. Kết quả: Cao 45% hơn 96%. Thành chính (>3%) gồm: Estragol,...
Objective: Alpinia is a big genus of flowering plants in the family Zingiberaceae. The this are generally aromatic due to their essential oils. current study aims identify chemical compositions rhizome and leaf oils vietnamica H.Đ. Trần, Luu & Škorničk. Methods: Essential A rhizomes leaves obtained by hydrodistillation were investigated gas chromatography–flame ionization detection/mass spectrometry (GC–FID/MS) analysis. have been subjected cytotoxic α-glucosidase inhibitory assays....
Previously, we isolated four known diterpenoids, trans-communic acid (1), 13-oxo-15,16-dinor-labda-8(17), 11E-diene-19-oic (2), 3β-hydroxytotarol (3), and totarolone (4) from Fokienia hodginsii leaves. Further study demonstrated the antiproliferative activity of all compounds in acute myeloid leukemia (OCI-AML) cells due to impaired cell cycle progression. Interestingly, (3) had very powerful bioactivity at low concentrations (5 µg/mL).
This study was carried out to verify and evaluate a method quantify the relative Sudan I color product using ultra-high performance liquid chromatography coupled with tandem massspectrometry (UPLC/MS/MS). extracted through an Oasis HLB 3cc Vac Cartridge solid phase extraction column 60 mg, after that quantified by UPLC/MS/MS. The program uses C18 (2.1 x 100 mm, 1.7 µm), mobile is acetonitrile water containing 0.1% formic acid, flow rate 0.4 ml/min. Running conditions of MRM (Multiple...
AbstractIn connection with our interest in the phytochemical investigation of Elaeocarpus hainanensis Oliv. (Elaeocarpaceae) growing Vietnam, two new sulphated oleanane triterpenes were obtained herein and structurally identified. Based on combination extensive 1D-, 2D NMR HR ESI MS spectroscopic data analysis, their chemical structures have been elucidated as 1α,3β-dihydroxy-olean-18-ene 1-sulphate (1) 1α,3β-dihydroxy-olean-12-ene (2). Notably, compounds 1 2 are corroborating proposition...