A5010660760- Colorectal Cancer Surgical Treatments
- Anorectal Disease Treatments and Outcomes
- Colorectal and Anal Carcinomas
- Diverticular Disease and Complications
- Neuroendocrine Tumor Research Advances
- Colorectal Cancer Screening and Detection
- Cardiac, Anesthesia and Surgical Outcomes
- Appendicitis Diagnosis and Management
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Treatments and Studies
- Immune Response and Inflammation
- Stoma care and complications
- Enhanced Recovery After Surgery
- Amoebic Infections and Treatments
- Pelvic floor disorders treatments
- Helicobacter pylori-related gastroenterology studies
- Nitric Oxide and Endothelin Effects
- PI3K/AKT/mTOR signaling in cancer
- Advanced Neural Network Applications
- Gastrointestinal disorders and treatments
- Autonomous Vehicle Technology and Safety
- Pineapple and bromelain studies
- Intestinal Malrotation and Obstruction Disorders
- Frailty in Older Adults
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
National Forensic Sciences University
2021
Harbor–UCLA Medical Center
2004-2015
UCLA Medical Center
2003-2015
Colon and Rectal Surgery Associates
2011
American Society of Colon and Rectal Surgeons
2011
University of California, Irvine Medical Center
2007
Los Angeles Medical Center
2007
University of Vermont Medical Center
2007
University of California, Los Angeles
2007
Yale University
1992-1995
Steele, Scott R. M.D.; Kumar, Ravin Feingold, Daniel L. Rafferty, Janice Buie, W. Donald M.D. Author Information
Ligation of intersphincteric fistula tract is a novel surgical technique in the treatment transsphincteric fistula-in-ano that has been shown to be successful short term. Median follow-up current literature ranges from 5 9 months. However, long-term success rate unknown.This study describes our results performing ligation procedure.This retrospective review.Thirty-eight patients August 2008 October 2011 were evaluated.All underwent for fistula-in-ano.Patient and characteristics, primary...
There is no definite consensus on the management of intra-abdominal abscesses in adults. This retrospective study evaluated use antibiotic therapy and percutaneous image-guided drainage adult patients with abscesses.A chart review 114 was conducted. Data collected included patient demographics, presenting symptoms, radiographic interpretation, vital signs, coverage, laboratory values, details hospital course. Bivariate statistical tests were performed using Wilcoxon rank-sum test,...
The ligation of the intersphincteric fistula tract is a new surgical procedure without any use biologic material. purpose this study to present our early results with novel technique.A retrospective review patients who underwent for high transsphincteric fistulas was analyzed. performed by single surgeon. Patient and characteristics, complications, recurrences were reviewed.Twenty-five procedure. All had that not suitable fistulotomy. on an outpatient basis median follow-up 24 weeks (range,...
Tjandra, Joe J. M.D.; Dykes, Sharon L. Kumar, Ravin R. Ellis, Neal C. Gregorcyk, G. Hyman, Neil H. Buie, Donald W. M.D. the Standards Practice Task Force of The American Society Colon and Rectal Surgeons Author Information
Abstract Objective The management of stage IV colorectal cancer is controversial. Resection the primary tumour to prevent obstruction, bleeding or perforation traditional approach, although survival benefit undetermined. Management consisting diverting ostomy, enteric bypass, laser recanalization endoscopic stenting an alternative radical resection. purpose this study was determine role resection in patients with cancer, specific attention paid and safety. Method This a retrospective review...
The status of lymph nodes is the most important prognosticator in colorectal cancer patients. Patients with node involvement have a lower survival rate and are candidates for adjuvant therapy. purpose our study was to determine number that needs be examined accurately detect nodal metastasis. We conducted retrospective 151 patients who underwent operation at Harbor-UCLA Medical Center. Data from operative report pathology were collected analyzed. Fourteen (33.3%) five nine had positive...
Despite advances in perioperative care and operative techniques, urgent colorectal operations are associated with higher morbidity mortality. To evaluate our rate of complications elective operations, we performed retrospective chart review 209 consecutive patients who underwent resection between 1998 2002 at Harbor-UCLA Medical Center. One hundred, forty-three (71%) resection. A total 19 (13.3%) occurred the group, compared 24 (38.1%) group (P = 0.003). Both right-sided left-sided were...
Stoma complications are common. Most do not require reoperation, but when surgery is indicated, numerous options available. Complications can arise early or late, and they vary from benign to life-threatening. Meticulous preoperative planning crucial in preventing stoma complications. Good communication with the patient important decision-making process.
Objective To define whether endothelin-1, a peptide produced by injured/ischemic endothelium, has any effect on monocyte intracellular calcium and the production of interleukin (IL)-1 IL-6. Design Prospective controlled laboratory study. Human monocytes from healthy donors were assayed for fluorometry stimulated 24 hrs in tissue culture with purified endotoxin or endothelin. Setting Veterans Affairs Medical Center surgical critical care basic science laboratory. Measurements Main Results...
The popularity of Bayesian statistical methods has increased dramatically in recent years across many research areas and industrial applications. This is the result a variety methodological advances with faster cheaper hardware as well development new software tools. Here we introduce an open source Python package named Bambi (BAyesian Model Building Interface) that built on top PyMC probabilistic programming framework ArviZ for exploratory analysis models. makes it easy to specify complex...
Histamine-secreting enterochromaffin-like (ECL) cells of the gastric fundus Mastomys can develop into solid ECL cell tumors, either spontaneously or after induction by acid inhibition. We used this tumor tissue to perform in vitro receptor autoradiography for somatostatin (SS), gastrin, and substance-P, using, respectively, [125I]Tyr3-octreotide, [125I]gastrin-17, [125I]Bolton-Hunter-labeled substance-P as radioligands. A high density SS receptors was found nontumor fundic mucosa, where...
Colorectal cancer (CRC) is a disease primarily affecting an older population. The incidence of CRC in young patients has been rising. purpose this study was to evaluate the characteristics ethnically diverse, Two groups with (40 years old or younger and 60 older) treated from 1998 2005 were retrospectively evaluated. Forty-one identified. Hispanics constituted 51 per cent Forty-four lesions right-sided group compared 21 (P = 0.004). Advanced tumor stage (T3 T4) noted 87.8 63 0.002; OR,...
The purpose of this study was to review and characterize the indications early outcomes abdominoperineal resection (APR) when used in a colorectal practice an academic setting. Data collected from charts all patients undergoing APR retrospective manner. included demographic information details regarding clinical presentation. Operative factors, postoperative course, morbidity mortality were evaluated. Forty-four treated with between years 1992 2004. for operation primary rectal cancer (n =...
Endothelin-1 (ET-1) is a vasoconstrictive peptide released by ischemic/injured endothelium which increases intracellular ionized calcium (Ca2+]i in vascular smooth muscle. Previous work from this lab has shown that ET-1 also human peripheral blood monocyte [Ca2+]i, and 24 h incubation of monocytes with 10-9 M causes production prostaglandin E2 interleukin-6. In these studies, ET-1-stimulated supernatants were evaluated for their effect on neutrophil superoxide production. While alone had no...