A5003847915- Metal Extraction and Bioleaching
- Genomics and Phylogenetic Studies
- Minerals Flotation and Separation Techniques
- Algal biology and biofuel production
- Genomics and Chromatin Dynamics
- Corrosion Behavior and Inhibition
- Photosynthetic Processes and Mechanisms
- Mine drainage and remediation techniques
- Mineral Processing and Grinding
- Identification and Quantification in Food
- Microbial infections and disease research
- Protist diversity and phylogeny
- Epigenetics and DNA Methylation
- RNA modifications and cancer
- Bacterial Genetics and Biotechnology
- Bacterial biofilms and quorum sensing
- Bacteriophages and microbial interactions
- Radioactive element chemistry and processing
- Metalloenzymes and iron-sulfur proteins
Fundación Ciencia and Vida
2019-2024
San Sebastián University
2020-2023
Millennium Science Initiative
2019-2021
Abstract Members of the genus Acidithiobacillus, now ranked within class Acidithiobacillia, are model bacteria for study chemolithotrophic energy conversion under extreme conditions. Knowledge genomic and taxonomic diversity Acidithiobacillia is still limited. Here, we present a systematic analysis nearly 100 genomes from sampled wide range habitats. Some these new others have been reclassified on basis advanced analysis, thus defining 19 lineages ranking at different levels. This work...
Plasmids are major drivers of microbial evolution, enabling horizontal gene transfer and facilitating adaptation through the dissemination relevant genes traits. Little is known about plasmid diversity function in extremophiles. 'Fervidacidithiobacillus caldus' a meso-thermo-acidophilic sulfur oxidizer, key player cycling acidic environments. Here, we present comprehensive analysis plasmidome, associated anti-mobile genetic element defense systems, across genomes this species metagenomes...
Abstract Horizontal gene transfer plays a critical role in microbial genome evolution and adaptation. Integrated foreign DNA fragments encompass various types of mobile genetic elements (MGEs), ranging from small transposons to conspicuous integrative conjugative elements. These regions often confer advantageous traits, including antibiotic resistance or novel metabolic capabilities, contain sequence signatures hallmark genes such as transposases, integrases, etc. While bioinformatic tools...
Cyclic and linear nucleotides are key elements of the signal transduction networks linking perception environment to specific cellular behavior prokaryotes. These molecular mechanisms particularly important in bacteria exposed different, frequently simultaneous, types extreme conditions. This is case acidithiobacilli, a group extremophilic thriving highly acidic biotopes, that must also cope with significant variations temperature, osmotic potentials concentrations various transition metals...
A novel acidophilic member of the phylum Actinobacteria was isolated from an acidic, metal-contaminated stream draining abandoned underground coal mine (Trongol mine), situated close to Curanilahue, Biobío Region, Chile. The isolate (USS-CCA1T) demonstrated be a heterotroph that catalysed under aerobic conditions oxidation ferrous iron and reduction ferric anaerobic conditions, but not sulfur nor hydrogen. USS-CCA1T is Gram-positive, motile, short rod-shaped, mesophilic bacterium with...
Acetobacteraceae are one of the best known and most extensively studied groups bacteria, which nowadays encompasses a variety taxa that very different from vinegar-producing species defining family. Our paper presents detailed phylogeny all current classified as Acetobacteraceae, for we propose taxonomic revision. Several such inhabit some extreme environments on planet, deserts Antarctica to Sinai desert, well acidic niches in volcanic sites like have been studying Patagonia. work documents...
Maintaining a proper supply of soluble histones throughout the cell cycle is important to ensure chromatin and genome stability. Following their synthesis, undergo series maturation steps prepare them for deposition onto chromatin.Here, we identify lysine demethylase JMJD1B as novel player in cascade that contributes regulate histone provision. We find depletion increases protein levels chaperone tNASP leading an accumulation newly synthesized H3 H4 at early cascade, which perturbs assembly....
Abstract The recent revision of the Acidithiobacillia class using genomic taxonomy methods has shown that, in addition to existence previously unrecognized genera and species, some species harbor levels divergence that are congruent with ongoing differentiation processes. In this study, we have performed a subspecies-level analysis sequenced strains Acidithiobacillus ferrooxidans prove distinct sublineages identify discriminant genomic/genetic characteristics linked these sublineages, shed...
Extreme acidophiles play central roles in the geochemical cycling of diverse elements low pH environments. This has been harnessed biotechnologies such as biomining, where microorganisms facilitate recovery economically important metals gold. By generating both extreme acidity and a chemical oxidant (ferric iron) many species prokaryotes that thrive environments not only catalyze mineral dissolution but also trigger community individual level adaptive changes. These changes vary extent...
Recent studies have expanded the genomic contours of Acidithiobacillia , highlighting important lacunae in our comprehension phylogenetic space occupied by certain lineages class. One such lineage is ‘ Igneacidithiobacillus’ a novel genus-level taxon, represented Igneacidithiobacillus copahuensis’ VAN18-1 T as its type species, along with two other uncultivated metagenome-assembled genomes (MAGs) originating from geothermally active sites across Pacific Ring Fire. In this study, we...