A5086505464- Intensive Care Unit Cognitive Disorders
- Family and Patient Care in Intensive Care Units
- Advanced Wireless Communication Techniques
- Frailty in Older Adults
- Respiratory Support and Mechanisms
- Advanced Statistical Methods and Models
- Error Correcting Code Techniques
- Bayesian Methods and Mixture Models
- Anesthesia and Sedative Agents
- Pharmaceutical Economics and Policy
- Silicon and Solar Cell Technologies
- Cardiac, Anesthesia and Surgical Outcomes
- Image and Signal Denoising Methods
- Seismic Imaging and Inversion Techniques
- Anesthesia and Neurotoxicity Research
- Tuberculosis Research and Epidemiology
- Energy Load and Power Forecasting
- HIV/AIDS Impact and Responses
- Healthcare Systems and Reforms
- Blind Source Separation Techniques
- Healthcare Decision-Making and Restraints
- Thin-Film Transistor Technologies
- Image and Object Detection Techniques
- Pharmaceutical Quality and Counterfeiting
- Cellular Automata and Applications
Humboldt-Universität zu Berlin
2020-2025
Charité - Universitätsmedizin Berlin
2020-2025
Freie Universität Berlin
2020-2025
Gemeinsamer Bundesausschuss
2024
Heidelberg University
2021-2024
University Hospital Heidelberg
2021-2024
Laboratoire Pluridisciplinaire de Recherche en Ingénierie des Systèmes, Mécanique et Energétique
2021-2024
Weatherford College
2023
ORCID
2023
Électricité de France (France)
2009-2021
There is no consensus on the instruments for diagnosis of post-intensive care syndrome (PICS). We present a proposal set outcome measurement PICS in outpatient care.We conducted three-round, semi-structured consensus-seeking process with medical experts, followed each by exploratory feasibility investigations intensive unit survivors (n1 = 5; n2 n3 7). Fourteen participants from nine stakeholder groups participated first and second meeting. In third meeting, core group six clinical...
Supporting the provision of intensive care medicine through telehealth potentially improves process quality. This may improve patient recovery and long-term outcomes. We investigated effectiveness a multifaceted telemedical programme on adherence to German quality indicators (QIs) in regional network units (ICUs) Germany. conducted an investigator-initiated, large-scale, open-label, stepped-wedge cluster randomised controlled trial enrolling adult ICU patients with expected stay ≥ 24 h....
Background and Objectives: In 2012, the umbrella term post-intensive care syndrome (PICS) was introduced to capture functional long-term impairments of survivors critical illness. We present a bibliometric network analysis PICS research field. Materials Methods: The Web Science core database searched for articles published in 2012 or later using 'post-intensive syndrome' variant spellings. Using VOSviewer, we computed co-authorship networks countries, institutions, authors, as well keyword...
To compare ICU survivors' subjective mental and functional health before admission after discharge to assess determinants of decline or improvement.
Objectives Chronic conditions and multimorbidity affect care needs prevention opportunities. Methods We studied 2,246 men women aged ≥40 years within the Dar es Salaam Urban Cohort Study from June 2017 to July 2018. Seventeen chronic were assessed based on self-report, body blood pressure measurement, tests, screening instruments. Results Hypertension (51.3%), anemia (34.1%), obesity (32.2%), diabetes (31.6%), depressive symptoms (31.5%), low grip strength (21.2%), ischemic heart disease...
Introduction Survival after critical illness has noticeably improved over the last decades due to advances in care medicine. Besides, there is an increasing number of elderly patients with chronic diseases being treated intensive unit (ICU). More than half survivors suffer from medium-term or long-term cognitive, psychological and/or physical impairments ICU discharge, which recognised as post-intensive syndrome (PICS). There are evidence-based and consensus-based quality indicators (QIs)...
Survivors of critical illness commonly show impaired health-related quality life (HrQoL). We investigated if HrQoL can be approximated by brief, easily applicable items to used in primary care.Secondary analysis data from the multicenter, cluster-randomized controlled Enhanced Recovery after Intensive Care trial ( ClinicalTrials.gov : NCT03671447) and construct validity study.Ten participating clusters ICUs metropolitan area Berlin, Germany.Eight hundred fifty ICU survivors enrolled a mixed,...
Midwifery services are a cornerstone of maternal care, but the mental health midwives is at risk in many work settings. The aim this study was to assess burnout and attitudes toward midwifery among Baden-Württemberg, Germany.
The introduction of new and often shorter tuberculosis (TB) drug regimens affects the cost TB programmes.
Tensor factorization models are widely used in many applied fields such as chemometrics, psychometrics, computer vision or communication networks. Real life data collection is often subject to errors, resulting missing data. Here we focus understanding how this issue should be dealt with for nonnegative tensor factorization. We investigate several criteria non-negative the case where some entries missing. In particular show smoothness penalties can compensate presence of values order ensure...
Background and objectives: The use of delirium screening instruments (DSIs) is recommended in critical care practice for a timely detection delirium. We hypothesize that the patient-related factors “level sedation” “mechanical ventilation” impact test validity DSIs. Materials Methods: This prospective, bi-center observational study (clinicaltrials.gov: NCT01720914). Critically ill patients were screened daily up to seven days after enrollment using Nursing Delirium Screening Scale (Nu-DESC),...
Tuberculosis (TB) programs depend on a continuous supply of large amounts high-quality TB drugs. When procure drugs from international suppliers, such as the Global Drug Facility, they can incur import costs for transport, customs clearance, and national transport. We assessed drug 18 longer (≥18 months), 10 shorter (9–12 8 short (≤6 months) regimens drug-sensitive (DS) multidrug-resistant (MDR)-TB treatment. Costs per regimen were estimated by multiplying recommended with 2021 Facility...
Abstract Background The objective of this study was to analyze the impact a structured educational intervention on implementation guideline-recommended pain, agitation, and delirium (PAD) assessment. Methods This prospective, multinational, interventional before-after trial conducted at 12 intensive care units from 10 centers in Germany, Austria, Switzerland, UK. Intensive underwent 6-week program, comprising online lectures, instructional videos, handouts, bedside teaching. Patient-level...
In this paper, we derived a new method to map various optoelectronic parameters of solar cells from voltage-dependent electroluminescence imaging. To get quantitative data, show how the voltage dependence mimics local diode current–voltage behavior, and propose way measure absolute flux. We therefore introduce calibration factor generally left unknown in literature. Example is shown on Al-BSF silicon cell for which several parameters: diffusion lengths, dark saturation current, voltages,...
Abstract Background Delirium screening instruments (DSIs) should be used to detect delirium, but they only show moderate sensitivity in patients with neurocritical illness. We explored whether, for these patients, DSI validity is impacted by patient-specific covariates. Methods Data were prospectively collected a single-center quality improvement project. Patients screened delirium once daily using the Intensive Care Screening Checklist (ICDSC) and Confusion Assessment Method Unit (CAM-ICU)....
Glucocorticoids rapidly provoke serotonin (5-HT) release in vivo. We aimed to investigate molecular mechanisms of glucocorticoid receptor (GR)-triggered 5-HT release.Employing 1C11 cells model neurotransmission, immunofluorescence and Pearson's Correlation Coefficient were used analyze colocalization GR, 5-HT, vesicle membrane protein synaptotagmin 1 dye FM4-64FX. FFN511 FM4-64FX dyes as well calcium imaging visualize vesicular upon application GR agonist dexamethasone, antagonist...