A5026611121- Cardiac Arrest and Resuscitation
- Trauma and Emergency Care Studies
- Mechanical Circulatory Support Devices
- Traumatic Brain Injury Research
- Respiratory Support and Mechanisms
- Emergency and Acute Care Studies
- Cardiac Structural Anomalies and Repair
- Dialysis and Renal Disease Management
- Urinary Tract Infections Management
- Anesthesia and Neurotoxicity Research
- Intensive Care Unit Cognitive Disorders
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Clinical Nutrition and Gastroenterology
- COVID-19 Clinical Research Studies
- Gut microbiota and health
- Injury Epidemiology and Prevention
- Vitamin D Research Studies
- Enhanced Recovery After Surgery
- Dysphagia Assessment and Management
- Extracellular vesicles in disease
- Heart Failure Treatment and Management
- Anesthesia and Sedative Agents
- Inflammatory Biomarkers in Disease Prognosis
- Food Allergy and Anaphylaxis Research
- Neutropenia and Cancer Infections
Medical University of Vienna
2015-2025
Vienna General Hospital
2018
Definitive guidelines for anticoagulation management during veno-venous extracorporeal membrane oxygenation (VV ECMO) are lacking, whereas bleeding complications continue to pose major challenges.
While prognostic values on survival after out-of-hospital cardiac arrest have been well investigated, less attention has paid to their age-specific relevance. Therefore, we aimed identify suitable early prognostication in elderly patients suffering order reduce the burden of unnecessary treatment and harm.In a prospective population-based observational trial individuals arrest, total 2223 receiving resuscitation attempts by local emergency medical service Vienna, Austria, were enrolled....
Extracorporeal cardiopulmonary resuscitation (eCPR) is a rescue therapy for selected patients when conventional (CPR) fails. Current evidence suggests that the success of eCPR depends on well-structured in- and out-of-hospital protocols. This article describes Vienna program, interventions implemented to improve clinical processes patient outcomes. In this retrospective study, we report all with inhospital cardiac arrest treated at our department between 2020 2023. During period, program was...
While guidelines mentioned supraglottic airway management in the case of out-of- hospital cardiac arrest, robust data their impact on patient outcome remain scare and results are inconclusive.To assess strategy we prospectively enrolled 2224 individuals suffering arrest who were treated by Viennese municipal emergency medical service. To control for potential confounders, propensity score matching was performed. Patients matched four groups with a 1:1:1:1 ratio ( n=210/group) according to...
Abstract Objectives Pulmonary thrombus formation is a hallmark of coronavirus disease 2019 (COVID-19). A dysregulated immune response culminating in thromboinflammation has been described, but the pathomechanisms remain unclear. Methods We studied 41 adult COVID-19 patients with positive results on reverse-transcriptase polymerase-chain-reaction assays and 37 sex- age-matched healthy controls. Number surface characteristics extracellular vesicles (EVs) citrullinated histone H3 levels were...
Laypersons' efforts to initiate basic life support (BLS) in witnessed Out-of-Hospital Cardiac Arrest (OHCA) remain comparably low within western society. Therefore, order shorten no-flow times cardiac arrest, several police-based first responder systems equipped with automated external defibrillators (Pol-AED) were established urban areas, which subsequently allow early BLS and AED administration by police officers. However, data on the quality of use such a system its impact patient outcome...
Abstract Background In the past urine was considered sterile. Through introduction of next generation sequencing, it has become clear that a urinary microbiome exists. Acute kidney injury (AKI) represents major threat to transplant recipients. Remarkable changes in metabolome occur during AKI, which may influence microbiome. To our knowledge, this is first study examines renal recipients (RTX) and non-transplant (nRTX) at time AKI. Methods cross-sectional pilot-study 21 RTX 9 nRTX with AKI...
BACKGROUND Early outcome prediction in out-of-hospital cardiac arrest is still a challenge. End-tidal carbon dioxide (ETCO2) has been shown to be reliable parameter reflect the quality of cardiopulmonary resuscitation and chance return spontaneous circulation (ROSC). OBJECTIVES This study assessed validity early capnography as predictive factor for ROSC survival victims with an underlying nonshockable rhythm. DESIGN Retrospective observational study. SETTING/PATIENTS During 2-year period,...
Novel drugs for Clostridium difficile (C. difficile) infections have been proven to reduce recurrent infections. Because of their high financial costs, identification patients at risk recurrence is essential provide optimal treatment. The ATLAS score's ability predict 90-day recurrence, disease complications and 1‑year all-cause mortality was evaluated. 144 consecutive symptomatic with positive stool test C. were enrolled. score (consisting the variables age, temperature, leukocyte count,...
We present a case of 52-year-old patient suffering from multi-phasic life-threatening anaphylaxis refractory to epinephrine treatment. Extracorporeal membrane oxygenation (ECMO) therapy was initiated as the ultima ratio stabilize hemodynamically during episodic severe bronchospasm. ECMO treatment successfully weaned after 4 days. Mastocytosis diagnosed underlying condition. Although is recommended first-line for anaphylaxis, this impressive provides clear evidence its limited therapeutic...
Abstract Background The objective of this study was to analyze the impact a structured educational intervention on implementation guideline-recommended pain, agitation, and delirium (PAD) assessment. Methods This prospective, multinational, interventional before-after trial conducted at 12 intensive care units from 10 centers in Germany, Austria, Switzerland, UK. Intensive underwent 6-week program, comprising online lectures, instructional videos, handouts, bedside teaching. Patient-level...
Vitamin D deficiency is frequent in cancer patients and a risk factor for morbidity mortality during critical illness. This single-center retrospective study analyzed 25-hydroxyvitamin levels critically ill (n = 178; hematologic, n 108; solid, 70) enrolled prospective ICU registry. The primary analysis was the prevalence of vitamin (<20 ng/mL) severe (≤12 ng/mL). Secondary analyses included factors its impact on ICU, hospital, 1-year mortality. 74% (95% CI: 67–80%) 54% 47–61%). Younger...
Background: Police first responder systems also including automated external defibrillation (AED) has in the past shown considerable impact on favourable outcomes after out-of-hospital cardiac arrest (OHCA). While short hands-off times chest compressions are known to be beneficial, various AED models use different algorithms, inducing longer or shorter durations of crucial timeframes along basic life support (BLS). Yet, data details these differences, and their potential clinical scarce....
The cornu ammonis 1 (CA1) region of the hippocampus is specifically vulnerable to global ischemia. We hypothesized that histopathological outcome in a ventricular fibrillation cardiac arrest (VFCA) rat model depends on time point examination.Male Sprague-Dawley rats were put into VFCA for 8 min, received chest compressions 2 and defibrillated achieve return spontaneous circulation. Animals surviving 80 14 days 140 compared with controls. Viable neurons counted 500 μm sector CA1 layer...
Allogeneic hematopoietic stem cell transplantation (HSCT) recipients are at risk of various complications during post-transplantation follow-up. Some patients may refer to an emergency department (ED) for medical attention, but data on ED visits by HSCT lacking. In the present study, we aimed assess utilization in and associated factors follow-up, identify subgroups presenting ED, analyze outcomes prognostic hospitalization 30-day mortality after visits, hazard following presentation. The...