A5056767810- Atrial Fibrillation Management and Outcomes
- Cardiac Arrest and Resuscitation
- Heart Failure Treatment and Management
- Acute Myocardial Infarction Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Arrhythmias and Treatments
- Cardiovascular Function and Risk Factors
- Trauma and Emergency Care Studies
- Emergency and Acute Care Studies
- Diabetes Treatment and Management
- Mechanical Circulatory Support Devices
- Cardiac Valve Diseases and Treatments
- Cardiac electrophysiology and arrhythmias
- Traumatic Brain Injury Research
- Cardiac Imaging and Diagnostics
- Cardiac, Anesthesia and Surgical Outcomes
- Potassium and Related Disorders
- Coronary Interventions and Diagnostics
- Cardiac Health and Mental Health
- Cardiac Structural Anomalies and Repair
- Inflammatory Biomarkers in Disease Prognosis
- Cardiac Fibrosis and Remodeling
- Lipoproteins and Cardiovascular Health
- Respiratory Support and Mechanisms
- Cardiac tumors and thrombi
Medical University of Vienna
2016-2025
Arbeitsgemeinschaft für Klinische Ernährung
2020-2022
Ludwig Boltzmann Cluster for Cardiovascular Research
2017-2018
Ludwig Boltzmann Institute for Digital Health and Prevention
2017-2018
Vienna General Hospital
2017-2018
Heidelberg University
2014-2015
University Hospital Heidelberg
2014-2015
University Hospital of Bern
2014-2015
Medical University of Graz
2014-2015
Synlab (Germany)
2014-2015
Background The ‘chain of survival’—including early call for help, cardiopulmonary resuscitation (CPR) and defibrillation—represents the most beneficial approach favourable patient outcome after out-of-hospital cardiac arrest (OHCA). Despite increasing numbers publicly accessible automated external defibrillators (AED) interventions to increase public awareness basic life support (BLS), number their use in real-life emergency situations remains low. Methods In this prospective...
Cardiovascular diseases (CVD) remain the leading cause of death worldwide and pharmacotherapy most them is suboptimal. Thus, there a clear unmet clinical need to develop new pharmacological strategies with greater efficacy better safety profiles. In this review, we summarize relevant advances in cardiovascular pharmacology 2022 including approval first-in-class drugs that open avenues for treatment obstructive hypertrophic cardiomyopathy (mavacamten), type 2 diabetes mellitus (tirzepatide),...
Recent evidence suggested levels of aspartate aminotransferase (AST), alanine transaminase (ALT), and AST/ALT ratio (De-Ritis ratio) were associated with a worse outcome after acute myocardial infarction (AMI). However, their value for predicting long-term prognosis remained unknown. Therefore, we investigated the prognostic potential transaminases on patient AMI from perspective.Data large registry including 1355 consecutive patients analyzed. The Cox regression hazard analysis was used to...
While prognostic values on survival after out-of-hospital cardiac arrest have been well investigated, less attention has paid to their age-specific relevance. Therefore, we aimed identify suitable early prognostication in elderly patients suffering order reduce the burden of unnecessary treatment and harm.In a prospective population-based observational trial individuals arrest, total 2223 receiving resuscitation attempts by local emergency medical service Vienna, Austria, were enrolled....
Abstract There is a strong and ever-growing body of evidence regarding the use pharmacogenomics to inform cardiovascular pharmacology. However, there no common position taken by international societies unite diverse availability, interpretation, application such data, nor recognition challenges variation in clinical practice between countries within Europe. Aside from considerable barriers implementing pharmacogenomic testing complexities clinically actioning results, are differences...
Background: In the era of personalized medicine, tools for risk stratification after cardiovascular interventions are crucial to reduce mortality and morbidity, especially in aging population. Biomarker-based approaches, particular, have gained significant importance. Mid-regional pro-adrenomedullin (MR-proADM) represents an easily assessable biomarker that mirrors cardiac function fibrosis. Therefore, we aimed investigate prognostic potential MR-proADM patients undergoing elective surgery....
Abstract Despite substantial advances in cardiovascular pharmacotherapy and devices recent years, prevention treatment of many diseases (CVD) remain limited, thus reflecting the need for more effective safer pharmacological strategies. In this review, we summarize most relevant studies 2024, including approval first-in-class drugs resistant hypertension pulmonary arterial hypertension, label expansions bempedoic acid semaglutide, results major randomised clinical trials (RCTs) that have met...
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing disease 2019 (COVID-19) can damage the endothelium and increase arterial stiffness, potentially leading to adverse cardiovascular events. In parallel, systemic inflammation in COVID-19 also impacts endothelial function. Angiotensin-converting enzyme (ACE2) promotes vasodilation anti-inflammatory effects, but facilitates SARS-CoV-2 entry into human cells. Thus, concerns have been raised about use of RAAS...
Strategies to improve risk prediction are of major importance in patients with heart failure (HF). Fibroblast growth factor 23 (FGF-23) is an endocrine regulator phosphate and vitamin D homeostasis associated increased cardiovascular risk. We aimed assess the prognostic effect FGF-23 on mortality HF a particular focus differences between preserved ejection fraction reduced (HFrEF).FGF-23 levels were measured 980 enrolled Ludwigshafen Risk Cardiovascular Health (LURIC) study including 511...
While guidelines mentioned supraglottic airway management in the case of out-of- hospital cardiac arrest, robust data their impact on patient outcome remain scare and results are inconclusive.To assess strategy we prospectively enrolled 2224 individuals suffering arrest who were treated by Viennese municipal emergency medical service. To control for potential confounders, propensity score matching was performed. Patients matched four groups with a 1:1:1:1 ratio ( n=210/group) according to...