A5022057246- Transcranial Magnetic Stimulation Studies
- Acute Kidney Injury Research
- Hemodynamic Monitoring and Therapy
- Muscle activation and electromyography studies
- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Poisoning and overdose treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Shoulder Injury and Treatment
- Innovations in Medical Education
- Sepsis Diagnosis and Treatment
- Renal function and acid-base balance
- Ultrasound in Clinical Applications
- Cardiac, Anesthesia and Surgical Outcomes
- Vestibular and auditory disorders
- Peripheral Nerve Disorders
- Heart Failure Treatment and Management
- Neurological disorders and treatments
- Higher Education Practises and Engagement
- ECG Monitoring and Analysis
- Tendon Structure and Treatment
- Antibiotics Pharmacokinetics and Efficacy
- Cervical and Thoracic Myelopathy
- Neural dynamics and brain function
- Muscle and Compartmental Disorders
Fiona Stanley Hospital
2016-2023
The University of Western Australia
1983-2016
Royal Perth Hospital
2012-2016
Queen Elizabeth II Medical Centre
1983-2015
Perron Institute for Neurological and Translational Science
2012-2015
Sir Charles Gairdner Hospital
1983
Background: In medical education, peer-assisted learning (PAL) refers to teaching occurring between fellow students. Few descriptions of its use teach clinical examination have been published. Student Grand Rounds (SGR) is a student-led initiative whereby senior students volunteer pre-clinical peers. tutors attend modified Teaching on the Run (TOTR) course originally designed train clinicians and junior doctors.Aim: We investigated value SGR in students, evaluated effectiveness TOTR.Methods:...
The authors assessed the risk factors and outcomes associated with blood-brain barrier (BBB) disruption in patients severe, nonpenetrating, traumatic brain injury (TBI) requiring decompressive craniectomy.At 2 major neurotrauma centers Western Australia, a retrospective cohort study was conducted among 97 adult who required an external ventricular drain (EVD) craniectomy during 2004-2012. Glasgow Outcome Scale scores were used to assess neurological outcomes. Logistic regression identify BBB...
Furosemide, a loop diuretic, is used to increase urine output in patients with acute kidney injury (AKI). It remains uncertain whether the benefits of furosemide AKI outweigh its potential harms. We investigated if influenced oxidative stress 30 critically ill by measuring changes F2-isoprostanes (F2-IsoPs), markers vivo stress, plasma and following intravenous furosemide. Urine F2-IsoPs were higher sepsis (p = 0.001) increased proportion 0.001). The furosemide-induced differed depending on...
Objectives: This study assessed the determinants of urinary output response to furosemide in acute kidney injury; specifically, whether is related altered pharmacokinetics or pharmacodynamics. Design: Prospective cohort. Setting: Tertiary ICU. Patients: Thirty critically ill patients with injury without preexisting renal impairment recent diuretic exposure. Intervention: A single dose IV furosemide. Measurements and Main Results: Baseline markers intravascular volume status were obtained...
The central venous-arterial carbon dioxide tension gradient (‘CO 2 gap’) has been shown to correlate with cardiac output and tissue perfusion in septic shock. Compared venous oxygen saturation (S CV O ), the CO gap is less susceptible effect of hyperoxia may be particularly useful as an adjunctive haemodynamic target perioperative period. This study investigated whether a high was associated increased systemic extraction (O ER >0.3) or occult hypoperfusion 201 patients immediate...
The acute onset of neck pain and arm weakness is most commonly due to cervical radiculopathy or inflammatory brachial plexopathy. Rarely, extracranial vertebral artery dissection may cause in the absence brainstem ischemia. We describe a case presenting as previously healthy 43-year-old woman who presented with proximal left aggravated by movement. Cervical magnetic resonance imaging (MRI) angiography revealed an intramural hematoma compressing C5 C6 nerve roots. Antiplatelet treatment was...
Optimising perioperative haemodynamic status may reduce postoperative complications. In this prospective prevalence study, we investigated the associations between standard parameters and a low central venous oxygen saturation (ScvO 2 ) in patients after major surgery. A total of 201 requiring continuous arterial pressure monitoring surgery were recruited. Simultaneous blood gases, biochemical data perfusion index obtained from at single time-point within 24 hours ScvO (<70%) was observed...
To examine long-term outcomes of Botulinum toxin type A (BoNT-A) injection to vastus lateralis (VL) for refractory anterior knee pain (AKP).Two cohorts (private clinic referrals and previous research participants) injected with BoNT-A AKP by one neurologist were surveyed retrospectively. Primary self-reported benefit, duration symptom relief, surgery post-injection. Secondary changes in utilization medication/physiotherapy treatment, symptoms activity limitation.Overall, average was 76...
A 63-year-old female presented late with anterior ST-elevation myocardial infarction and cardiogenic shock. This was complicated by acute ventricular septal defect large left-to-right shunt. An Impella CP inserted on day seven rapid haemodynamic improvement. facilitated bridge to cardiac transplant twelve post-MI.
Abstract Background Left ventricular (LV) assist devices (LVADs) can prolong survival and improve quality of life in end‐stage heart failure. Aims Review outcomes the Western Australian LVAD programme. Methods Retrospective database medical record review. Results One hundred forty‐seven LVADs have been implanted 23 years, which 95 were newer‐generation (HeartWare HVAD [HW], HeartMate II 3). Presented data refer to these only. Most patients (94%) classed as bridge‐to‐transplant or...