- Cardiac Structural Anomalies and Repair
- Mechanical Circulatory Support Devices
- Cardiovascular Function and Risk Factors
- Infective Endocarditis Diagnosis and Management
- Cardiac Arrest and Resuscitation
- Cardiac Valve Diseases and Treatments
- Heart Failure Treatment and Management
- Congenital Heart Disease Studies
- Infectious Encephalopathies and Encephalitis
- Transplantation: Methods and Outcomes
- Facial Rejuvenation and Surgery Techniques
- Dermatologic Treatments and Research
- Metabolism and Genetic Disorders
- Cardiac Imaging and Diagnostics
- Cardiovascular and exercise physiology
- Cardiac pacing and defibrillation studies
- Respiratory Support and Mechanisms
- Sex and Gender in Healthcare
- Adrenal and Paraganglionic Tumors
- Pharmaceutical industry and healthcare
- Hair Growth and Disorders
- NF-κB Signaling Pathways
- Nerve Injury and Rehabilitation
- Retinoids in leukemia and cellular processes
- Genomics and Chromatin Dynamics
University of British Columbia
2024
Curtin University
2010-2024
Fiona Stanley Hospital
2016-2024
Hong Kong Adventist Hospital
2024
University of Toronto
2018-2021
Royal Perth Hospital
2010-2015
Institute of Cardiology
2014
Sir Charles Gairdner Hospital
2011
Radboud University Nijmegen
2010
The University of Western Australia
2010
Exercise training is an important adjunct to medical therapy in chronic heart failure, but the extent which exercise impacts on conduit artery remodeling unknown. The aim of this study was evaluate impact aerobic and resistance modalities arterial patients with failure. We randomized 36 untrained subjects failure (58.8 ± 3.5 years), (61.3 2.8 or control group (64.4 2.4 years). Peak oxygen consumption during cycle ergometry increased after 12 weeks both (P < 0.001) groups, not controls,...
Right ventricular failure (RVF) is common after left assist device (LVAD) implantation and a major determinant of adverse outcomes. Optimal perioperative right (RV) management not well defined. We evaluated the use pulmonary vasodilator therapy during LVAD implantation. performed retrospective analysis continuous-flow implants at our institution between September 2004 June 2013. Preoperative RVF risk was assessed using recognized variables. Sixty-five patients (80% men, 50 ± 14 years) were...
Abstract Hyperammonemia syndrome (HS) is a life-threatening condition occurring in solid organ transplant patients, affecting primarily lung recipients, and associated with Mycoplasma hominis and/or Ureaplasma spp infection. The donor was young man who died of hypoxic brain injury had urethral discharge antemortem. 4 recipients infection M spp. heart both developed altered conscious state HS infections. Despite treatment antibiotics ammonia scavengers, the at day +102 +254, respectively....
Background— Ischemic mitral regurgitation (MR) results from displacement of the papillary muscles caused by ischemic ventricular distortion. Progressive left (LV) remodeling has challenged therapy. Our hypothesis is that repositioning can be achieved injection polyvinyl-alcohol (PVA) hydrogel polymer into myocardium in chronic MR despite advanced LV remodeling. Methods and Results— Ten sheep underwent ligation circumflex branches to produce over 8 weeks. PVA was injected underlying infarcted...
Mitral regurgitation (MR) is the second most common valvular disease in western countries after aortic stenosis. Optimal management of patients with MR depends on etiology and based predominantly left ventricular function functional status. Recent outcome studies report high risk subsets asymptomatic MR, practice guidelines underscore importance a well-established estimation exercise tolerance recommend testing to objectively assess status hemodynamic factors.
ABSTRACT Purpose Childhood leukemia survivors commonly develop late-onset cardiovascular disease after treatment with anthracyclines. Resting echocardiogram is the standard procedure for monitoring cardiac health but this method may not be sensitive enough to detect subclinical injury. Exercise echocardiography provide a viable alternative. Methods Nineteen (9 males; age, 19 ± 3 yr) anthracycline-treated of childhood and 17 (8 males) healthy individuals similar age (22 2 were recruited. All...
We report successful management of left atrial hematoma after ablation supraventricular tachycardia. A 43-year-old female patient experienced chest pain immediately radiofrequency a symptomatic posterolateral accessory pathway. Transthoracic echocardiography demonstrated large mass occupying the atrium. Computed tomography and transesophageal results were consistent with intramural hematoma. She became hemodynamically unstable, requiring emergent surgery. The resolved completely by 6 weeks....
A 47-year-old man was admitted to this hospital because of abdominal pain 5 weeks' duration, which radiated the flank. He had intermittent and constipation for 15 years. born in Central America lived rural urban areas until immigrating United States more than 25 years before admission. Computed tomography abdomen revealed renal abnormalities consistent with infarcts. Echocardiography a left ventricular aneurysm thrombus. diagnostic test performed.
A 63-year-old female presented late with anterior ST-elevation myocardial infarction and cardiogenic shock. This was complicated by acute ventricular septal defect large left-to-right shunt. An Impella CP inserted on day seven rapid haemodynamic improvement. facilitated bridge to cardiac transplant twelve post-MI.
Due to improved therapy in childhood, many patients with congenital heart disease reach adulthood and are termed adults (ACHD). ACHD often develop failure (HF) as a consequence of initial palliative surgery or complex anatomy subsequently require advanced HF therapy. usually excluded from trials evaluating therapies, this context, more data about trajectories needed guide the management suffering HF.The pAtients pResenTing cOngenital heaRt dIseAse Register (ARTORIA-R) will collect evaluated...
A 59-year-old male patient was referred to our centre after a scheduled outpatient echocardiogram demonstrated that he had left ventricular (LV) pseudoaneurysm. The reported chest pain and dyspnea on exertion. He history of delayed presentation myocardial infarction (MI) 6 months prior, with negative cardiac troponin at presentation. At the time MI, smoker but no other past medical note. Percutaneous intervention, placement drug-eluting stent severe mid anterior descending artery lesion...
Background: Dibothriocephalus nihonkaiense (previously known as Diphyllobothrium nihonkaiense) infection is not common in Hong Kong. D. a fish-borne cestode parasite that infects humans after consuming raw or insufficiently cooked fish containing plerocercoids. Case presentation: We reported case of 40-year-old woman who presented with complaint epigastric pain and diarrhea. A curvilinear opacity was seen at the upper quadrant abdomen via abdominal X-ray. An incomplete 80 cm long strobila...