A5075360371- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiovascular Function and Risk Factors
- Cardiac Structural Anomalies and Repair
- Soft Robotics and Applications
- Cardiac pacing and defibrillation studies
- Cardiac Imaging and Diagnostics
- Modular Robots and Swarm Intelligence
- Aortic Disease and Treatment Approaches
- Congenital Heart Disease Studies
- Robot Manipulation and Learning
- Antimicrobial Resistance in Staphylococcus
- Robotics and Automated Systems
- Cardiovascular and Diving-Related Complications
- Robotic Locomotion and Control
- Nuclear and radioactivity studies
- Cardiomyopathy and Myosin Studies
- Cardiac Arrhythmias and Treatments
- Cardiovascular Health and Disease Prevention
- Nuclear reactor physics and engineering
- Airway Management and Intubation Techniques
- Congenital heart defects research
- Surgical Simulation and Training
- Nuclear Materials and Properties
- Cardiac tumors and thrombi
Centro de Investigación en Red en Enfermedades Cardiovasculares
2019-2025
Research Institute Hospital 12 de Octubre
2017-2025
Instituto de Salud Carlos III
2020-2025
Hospital Universitario 12 De Octubre
2018-2024
Clínica Rementería
2023-2024
Centro de Investigación Biomédica en Red
2020-2024
Camilo José Cela University
2024
HM Hospitales
2018-2024
Universidad Complutense de Madrid
2013-2023
Hospital Juan Ramón Jiménez
2023
Two-dimensional echocardiographic (2DE) continuity-equation derived aortic valve area (AVA) in stenosis (AS) relies on non-simultaneous measurement of left ventricular outflow tract (LVOT) velocity and geometric assumptions LVOT area, which can amplify error, especially upper septal hypertrophy (USH). We hypothesized that real-time three-dimensional echocardiography (RT3DE) improve accuracy AVA by directly measuring stroke volume (SV) one window.RT3DE colour Doppler 2DE were acquired 68 AS...
Cardiac resynchronization therapy (CRT) has been shown to reduce functional mitral regurgitation (MR). It proposed that the mechanism of MR reduction relates geometric change or, alternatively, changes in left ventricular (LV) contractile function. Normal valve (MV) function relies on a balance between tethering and closing forces MV leaflets. Functional results from derangement this force-balance relationship, CRT may be an important modulator by its ability enhance relationship MV. We...
Abstract Aims To evaluate echocardiographic and biomarker changes during chemotherapy, assess their ability to early detect predict cardiotoxicity define the best time for evaluation. Methods results Seventy‐two women with breast cancer (52 ± 9.8 years) treated anthracyclines (26 also trastuzumab), were evaluated 14 months (6 echocardiograms/12 laboratory tests). We analysed: high‐sensitivity cardiac troponin T, NT‐proBNP, global longitudinal strain (GLS), left ventricle end‐systolic volume...
Abstract Introduction Arrhythmic Mitral Valve Prolapse (AMVP) constitutes a subgroup of (MVP) patients who, without necessarily having significant insufficiency, exhibit an increased risk malignant ventricular arrhythmias (VA). Although this entity has recently gained attention in the scientific community, its pathophysiology and phenotypic characterization remain not completely elucidated. It been postulated that leaflet displacement increases tension on papillary muscles (PM), causing...
Objective To compare the risk of cardiovascular disease and occurrence events in mid-long term after delivery, between women with without a history early-onset preeclampsia.
Background Cardiovascular (CV) disease is the leading cause of death in women. Although 80% CV events can be prevented, mortality projected to increase, particularly young Objectives To promote health women and encourage appropriate lifestyle changes by increasing awareness through vascular ultrasound imaging. Methods WAKE UP a prospective case-control study target population 720 asymptomatic women, aged 40–70 years with ≥1 major risk factor (RF). Participants will attend baseline visit...
Cardiac dysfunction and arrhythmia are common onerous cardiovascular events in end-stage renal disease (ESRD) patients, especially those on dialysis. Fibroblast growth factor (FGF)-23 is a phosphate-regulating hormone whose levels dramatically increase as function declines. Beyond its role phosphorus homeostasis, FGF-23 may elicit direct effect the heart. Whether modulates ventricular cardiac rhythm unknown, prompting us to study excitation-contraction (EC) coupling.We examined vitro actions...
Background Mitral valve prolapse (MVP) is a common heart disease, the most frequent indication for repair or replacement. MVP characterized by excess extracellular matrix secretion and cellular disorganization, which leads to bulky valves that are unable coapt correctly during ventricular systole resulting in mitral regurgitation, it associated with sudden cardiac death. Here we aim characterize globally biological mechanisms underlying genetic susceptibility better its triggering...
Background Percutaneous closure of paravalvular leak (PVL) has emerged as an alternative treatment. Predictors survival and procedural success are unknown. Objectives To review our experience in the treatment PVL evaluate efficacy, mortality, predictors success, outcomes. Methods Retrospective percutaneous procedures between years 2008 2014. Survival results were compared with a control cohort surgical patients. Results was attempted 51 The group had 36 Defects perimitral 67 patients (77%)....
Haptic interfaces have been used as cooperative systems to reproduce and simulate human actions. The Interface (HI) can be a tool capable of interacting dynamically with the operator using Reactive Robot (RR) technology. RR provide HI capability interpreting actions exert more intelligent force feedback strategy. This paper deals an application theory leach people write Japanese characters, desktop III designed at PERCRO. In this article, we will outline main features system. Human action...
A 39-year-old-man presented to the Emergency Department after 5 days of fever, cough, myalgia, oppressive chest pain, and dyspnoea at rest.He had no cardiovascular risk factors or relevant past medical history.On admission, he a temperature 38.9 C, blood pressure 127/71 mmHg, heart rate 112 b.p.m., oxygen saturation 89%.Physical exam revealed decreased breath sounds base lungs.Chest X-ray showed multifocal bilateral patchy airspace opacities consistent with viral pneumonia (Panel...
Abstract Background Chronic kidney disease (CKD) is associated with increased propensity for arrhythmias. In this context, ventricular repolarization alterations have been shown to predispose fatal arrhythmias and sudden cardiac death. Between mineral bone disturbances in CKD patients, fibroblast growth factor (FGF) 23 decreased Klotho are emerging as important effectors of cardiovascular disease. However, the relationship between imbalanced FGF23-Klotho axis development remains unknown....
Left atrial (LA) remodeling after an acute myocardial infarction (MI) is poorly characterized regarding its determinants or effect on ischemic mitral regurgitation (MR) development. The purpose of this study was: 1) to compare LA structural in experimental MI swine models recapitulating the effects left ventricular (LV) dysfunction, MR, and (LAI); 2) analyze how influences MR Three were generated: proximal circumflex (LCx) coronary artery occlusion involving branch (LAI group); LCx not (LCx...
Mitral valve (MV) prolapse (MVP) is a primary valvular abnormality. We hypothesized that additionally there are concomitant abnormalities of the left ventricle (LV) and MV apparatus in this entity even absence significant mitral regurgitation (MR).