- Aortic Disease and Treatment Approaches
- Cardiac Valve Diseases and Treatments
- Aortic aneurysm repair treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Structural Anomalies and Repair
- Hip and Femur Fractures
- Congenital Heart Disease Studies
- Infective Endocarditis Diagnosis and Management
- Connective tissue disorders research
- Infectious Aortic and Vascular Conditions
- Cardiac Arrest and Resuscitation
- Non-Invasive Vital Sign Monitoring
- ECG Monitoring and Analysis
- Cardiac Imaging and Diagnostics
- Heart Failure Treatment and Management
- Mobile Health and mHealth Applications
- Cardiovascular Function and Risk Factors
- Hemodynamic Monitoring and Therapy
- Cardiovascular Issues in Pregnancy
- Healthcare Systems and Technology
- Ultrasound in Clinical Applications
- Cardiovascular and Diving-Related Complications
- Cardiovascular Effects of Exercise
- Aortic Thrombus and Embolism
- Healthcare Technology and Patient Monitoring
Massachusetts General Hospital
2016-2025
University of Michigan
2014-2024
Harvard University
2015-2024
Lemuel Shattuck Hospital
2021
Vall d'Hebron Hospital Universitari
2004-2020
Hadassah Medical Center
2012-2020
Washington University in St. Louis
2012-2020
Dr. Brill + Dr. Steinmann (Germany)
2011-2018
Methodist Hospital
2018
Technical University of Munich
2018
ContextAcute aortic dissection is a life-threatening medical emergency associated with high rates of morbidity and mortality. Data are limited regarding the effect recent imaging therapeutic advances on patient care outcomes in this setting.ObjectiveTo assess presentation, management, acute dissection.DesignCase series patients enrolled between January 1996 December 1998. were collected at presentation by physician review hospital records.SettingThe International Registry Acute Aortic...
The "2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease" provides recommendations to guide clinicians in diagnosis, genetic evaluation family screening, medical therapy, endovascular surgical treatment, long-term surveillance patients with aortic disease across its multiple clinical presentation subsets (ie, asymptomatic, stable symptomatic, acute syndromes).
Background— Studies of aortic aneurysm patients have shown that the risk rupture increases with size. However, few studies acute dissection and size exist. We used data from our registry to better understand relationship between diameter type A dissection. Methods Results— examined 591 enrolled in International Registry Acute Aortic Dissection 1996 2005 (mean age, 60.8 years). Maximum diameters averaged 5.3 cm; 349 (59%) had <5.5 cm 229 (40%) <5.0 cm. Independent predictors at smaller...
Follow-up survival studies in patients with acute type B aortic dissection have been restricted to a small number of single centers. We used data from contemporary registry better understand factors associated adverse long-term survival.We examined 242 consecutive discharged alive enrolled the International Registry Acute Aortic Dissection (IRAD) between 1996 and 2003. Kaplan-Meier curves were constructed, Cox proportional hazards analysis was performed identify independent predictors...
Patency or thrombosis of the false lumen in type B acute aortic dissection has been found to predict outcomes. The prognostic implications partial have not yet elucidated.We examined 201 patients with who were enrolled International Registry Acute Aortic Dissection between 1996 and 2003 survived hospital discharge. Kaplan-Meier mortality curves stratified according status (patent, thrombosis, complete thrombosis) as determined during index hospitalization. Cox proportional-hazards analysis...
Clinical profiles and outcomes of patients with acute type B aortic dissection have not been evaluated in the current era.Accordingly, we analyzed 384 (65+/-13 years, males 71%) enrolled International Registry Acute Aortic Dissection (IRAD). A majority had hypertension presented chest/back pain. Only one-half showed abnormal findings on chest radiograph, almost all computerized tomography (CT), transesophageal echocardiography, magnetic resonance imaging (MRI), and/or aortogram to confirm...
Background— Few data exist on gender-related differences in clinical presentation, diagnostic findings, management, and outcomes acute aortic dissection (AAD). Methods Results— Accordingly, we evaluated 1078 patients enrolled the International Registry of Acute Aortic Dissection (IRAD) to assess features, in-hospital between men women. Of IRAD (32.1%) with AAD, 346 were Although less frequently affected by AAD (32.1% AAD), women significantly older had more often presented later than ( P...
The definition, prevalence, outcomes, and appropriate treatment strategies for acute intramural hematoma (IMH) continue to be debated.We studied 1010 patients with aortic syndromes who were enrolled in the International Registry of Aortic Dissection (IRAD) delineate presentation, management, outcomes IMH by comparing these those classic dissection (AD). Fifty-eight (5.7%) had IMH, this cohort tended older (68.7 versus 61.7 years; P<0.001) more likely have distal involvement (60.3% 35.3%;...
The clinical profiles and outcomes of patients treated surgically for acute type B aortic dissection (ABAD) are often reported those in small series or cared at a single institution over long time period, during which continuous evolution techniques has occurred. Accordingly, we sought to evaluate the features surgical results enrolled International Registry Acute Aortic Dissection by identifying primary factors that influenced outcome estimating average mortality ABAD current era.A...
Background— In 2010, the American Heart Association and College of Cardiology released guidelines for diagnosis management patients with thoracic aortic disease, which identified high-risk clinical features to assist in early detection acute dissection. The sensitivity these risk markers has not been validated. Methods Results— We examined enrolled International Registry Acute Aortic Dissection from 1996 2009. number confirmed dissection who presented 1 or more 12 proposed was determined. An...