Eric M. Isselbacher

ORCID: 0000-0003-0393-168X
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About
Contact & Profiles
Research Areas
  • Aortic Disease and Treatment Approaches
  • Cardiac Valve Diseases and Treatments
  • Aortic aneurysm repair treatments
  • Cardiac, Anesthesia and Surgical Outcomes
  • Cardiac Structural Anomalies and Repair
  • Hip and Femur Fractures
  • Congenital Heart Disease Studies
  • Infective Endocarditis Diagnosis and Management
  • Connective tissue disorders research
  • Infectious Aortic and Vascular Conditions
  • Cardiac Arrest and Resuscitation
  • Non-Invasive Vital Sign Monitoring
  • ECG Monitoring and Analysis
  • Cardiac Imaging and Diagnostics
  • Heart Failure Treatment and Management
  • Mobile Health and mHealth Applications
  • Cardiovascular Function and Risk Factors
  • Hemodynamic Monitoring and Therapy
  • Cardiovascular Issues in Pregnancy
  • Healthcare Systems and Technology
  • Ultrasound in Clinical Applications
  • Cardiovascular and Diving-Related Complications
  • Cardiovascular Effects of Exercise
  • Aortic Thrombus and Embolism
  • Healthcare Technology and Patient Monitoring

Massachusetts General Hospital
2016-2025

University of Michigan
2014-2024

Harvard University
2015-2024

Lemuel Shattuck Hospital
2021

Vall d'Hebron Hospital Universitari
2004-2020

Hadassah Medical Center
2012-2020

Washington University in St. Louis
2012-2020

Dr. Brill + Dr. Steinmann (Germany)
2011-2018

Methodist Hospital
2018

Technical University of Munich
2018

ContextAcute aortic dissection is a life-threatening medical emergency associated with high rates of morbidity and mortality. Data are limited regarding the effect recent imaging therapeutic advances on patient care outcomes in this setting.ObjectiveTo assess presentation, management, acute dissection.DesignCase series patients enrolled between January 1996 December 1998. were collected at presentation by physician review hospital records.SettingThe International Registry Acute Aortic...

10.1001/jama.283.7.897 article EN JAMA 2000-02-16

Background— Studies of aortic aneurysm patients have shown that the risk rupture increases with size. However, few studies acute dissection and size exist. We used data from our registry to better understand relationship between diameter type A dissection. Methods Results— examined 591 enrolled in International Registry Acute Aortic Dissection 1996 2005 (mean age, 60.8 years). Maximum diameters averaged 5.3 cm; 349 (59%) had <5.5 cm 229 (40%) <5.0 cm. Independent predictors at smaller...

10.1161/circulationaha.107.702720 article EN Circulation 2007-08-21

Follow-up survival studies in patients with acute type B aortic dissection have been restricted to a small number of single centers. We used data from contemporary registry better understand factors associated adverse long-term survival.We examined 242 consecutive discharged alive enrolled the International Registry Acute Aortic Dissection (IRAD) between 1996 and 2003. Kaplan-Meier curves were constructed, Cox proportional hazards analysis was performed identify independent predictors...

10.1161/circulationaha.106.622340 article EN Circulation 2006-11-14

Patency or thrombosis of the false lumen in type B acute aortic dissection has been found to predict outcomes. The prognostic implications partial have not yet elucidated.We examined 201 patients with who were enrolled International Registry Acute Aortic Dissection between 1996 and 2003 survived hospital discharge. Kaplan-Meier mortality curves stratified according status (patent, thrombosis, complete thrombosis) as determined during index hospitalization. Cox proportional-hazards analysis...

10.1056/nejmoa063232 article EN New England Journal of Medicine 2007-07-25

Clinical profiles and outcomes of patients with acute type B aortic dissection have not been evaluated in the current era.Accordingly, we analyzed 384 (65+/-13 years, males 71%) enrolled International Registry Acute Aortic Dissection (IRAD). A majority had hypertension presented chest/back pain. Only one-half showed abnormal findings on chest radiograph, almost all computerized tomography (CT), transesophageal echocardiography, magnetic resonance imaging (MRI), and/or aortogram to confirm...

10.1161/01.cir.0000087386.07204.09 article EN Circulation 2003-09-09

Background— Few data exist on gender-related differences in clinical presentation, diagnostic findings, management, and outcomes acute aortic dissection (AAD). Methods Results— Accordingly, we evaluated 1078 patients enrolled the International Registry of Acute Aortic Dissection (IRAD) to assess features, in-hospital between men women. Of IRAD (32.1%) with AAD, 346 were Although less frequently affected by AAD (32.1% AAD), women significantly older had more often presented later than ( P...

10.1161/01.cir.0000130644.78677.2c article EN Circulation 2004-06-15

The definition, prevalence, outcomes, and appropriate treatment strategies for acute intramural hematoma (IMH) continue to be debated.We studied 1010 patients with aortic syndromes who were enrolled in the International Registry of Aortic Dissection (IRAD) delineate presentation, management, outcomes IMH by comparing these those classic dissection (AD). Fifty-eight (5.7%) had IMH, this cohort tended older (68.7 versus 61.7 years; P<0.001) more likely have distal involvement (60.3% 35.3%;...

10.1161/01.cir.0000156444.26393.80 article EN Circulation 2005-02-15

The clinical profiles and outcomes of patients treated surgically for acute type B aortic dissection (ABAD) are often reported those in small series or cared at a single institution over long time period, during which continuous evolution techniques has occurred. Accordingly, we sought to evaluate the features surgical results enrolled International Registry Acute Aortic Dissection by identifying primary factors that influenced outcome estimating average mortality ABAD current era.A...

10.1161/circulationaha.105.000620 article EN Circulation 2006-07-04

Background— In 2010, the American Heart Association and College of Cardiology released guidelines for diagnosis management patients with thoracic aortic disease, which identified high-risk clinical features to assist in early detection acute dissection. The sensitivity these risk markers has not been validated. Methods Results— We examined enrolled International Registry Acute Aortic Dissection from 1996 2009. number confirmed dissection who presented 1 or more 12 proposed was determined. An...

10.1161/circulationaha.110.988568 article EN Circulation 2011-05-10
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