Dean Karavite

ORCID: 0000-0003-0554-5715
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About
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Research Areas
  • Electronic Health Records Systems
  • Cardiac, Anesthesia and Surgical Outcomes
  • Genomics and Rare Diseases
  • Ethics in Clinical Research
  • Healthcare Technology and Patient Monitoring
  • BRCA gene mutations in cancer
  • Acute Myocardial Infarction Research
  • Health Literacy and Information Accessibility
  • Healthcare Policy and Management
  • Mobile Health and mHealth Applications
  • Health Systems, Economic Evaluations, Quality of Life
  • Health Policy Implementation Science
  • Aortic Disease and Treatment Approaches
  • Patient Safety and Medication Errors
  • Hemodynamic Monitoring and Therapy
  • Cardiovascular Function and Risk Factors
  • Clinical practice guidelines implementation
  • Aortic aneurysm repair treatments
  • Surgical site infection prevention
  • Cardiac Valve Diseases and Treatments
  • Emergency and Acute Care Studies
  • Sepsis Diagnosis and Treatment
  • Cardiac Imaging and Diagnostics
  • Healthcare Systems and Technology
  • Cancer Genomics and Diagnostics

Children's Hospital of Philadelphia
2016-2025

National Human Genome Research Institute
2013

National Institutes of Health
2013

Pediatrics and Genetics
2013

Temple University Hospital
2008

University of Michigan–Ann Arbor
1997-2003

Ann Arbor Center for Independent Living
2000-2002

IBM (United States)
2002

St Vincent's Hospital Sydney
1999

ContextAcute aortic dissection is a life-threatening medical emergency associated with high rates of morbidity and mortality. Data are limited regarding the effect recent imaging therapeutic advances on patient care outcomes in this setting.ObjectiveTo assess presentation, management, acute dissection.DesignCase series patients enrolled between January 1996 December 1998. were collected at presentation by physician review hospital records.SettingThe International Registry Acute Aortic...

10.1001/jama.283.7.897 article EN JAMA 2000-02-16
Gail P. Jarvik Laura M. Amendola Jonathan S. Berg Kyle B. Brothers Ellen Wright Clayton and 95 more Wendy K. Chung Barbara J. Evans James P. Evans Stephanie M. Fullerton Carlos J. Gallego Nanibaa’ A. Garrison Stacy W. Gray Ingrid A. Holm Iftikhar J. Kullo Lisa Soleymani Lehmann Catherine A. McCarty Cynthia A. Prows Heidi L. Rehm Richard R. Sharp Joseph K. Salama Saskia C. Sanderson Sara L. Van Driest Marc S. Williams Susan M. Wolf Wendy A. Wolf Wylie Burke John B. Harley Melanie F. Myers Bahram Namjou Alexander A. Vinks John J. Connolly Brendan J. Keating Glenn S. Gerhard Agnes S. Sundaresan Gerard Tromp David R. Crosslin Kathy Leppig Cathy Wicklund Christopher G. Chute John Lynch Mariza de Andrade John A. Heit Jen McCormick Murray H. Brilliant Terrie Kitchner Marylyn D. Ritchie Erwin P. Böttinger Inga Peter Stephen D. Persell Laura J. Rasmussen‐Torvik Tracy L. McGregor Dan M. Roden Armand H. Matheny Antommaria Rosetta Chiavacci Andy Faucett David H. Ledbetter Janet L. Williams Andrea L. Hartzler Carolyn R. Rohrer Vitek Norm Frost Kadija Ferryman Carol R. Horowitz Rosamond Rhodes Randi E. Zinberg Sharon Aufox Vivian Pan Rochelle M. Long Erin M. Ramos Jackie Odgis Anastasia L. Wise Sara Chandros Hull Jonathan Gitlin Robert C. Green Danielle R. Metterville Amy L. McGuire Sek Won Kong Sue Trinidad David L. Veenstra Myra I. Roche Debra Skinner Kelly Raspberry Julianne O’Daniel William H. Parsons Christine M. Eng Susan G. Hilsenbeck Dean Karavite Laura K. Conlin Nancy B. Spinner Ian D. Krantz Marni J. Falk Avni Santani Elizabeth T. DeChene Matthew C. Dulik Barbara A. Bernhardt Scott M. Schuetze Jessica N. Everett Michele C. Gornick Ben Wilfond Holly K. Tabor Amy A. Lemke

10.1016/j.ajhg.2014.04.009 article EN publisher-specific-oa The American Journal of Human Genetics 2014-05-08
Jodell E. Linder Aimee Allworth Harris T. Bland Pedro J. Caraballo Rex L. Chisholm and 95 more Ellen Wright Clayton David R. Crosslin Ozan Dikilitas Alanna J. DiVietro Edward D. Esplin Sophie Forman Robert R Freimuth Adam S Gordon Richard Green Maegan Harden Ingrid A. Holm Gail P. Jarvik Elizabeth W. Karlson Sofia Labrecque Niall J. Lennon Nita A. Limdi Kathleen F. Mittendorf Shawn N. Murphy Lori A. Orlando Cynthia A. Prows Luke V. Rasmussen Laura J. Rasmussen‐Torvik Robb Rowley Konrad Teodor Sawicki Tara Schmidlen Shannon Terek David L. Veenstra Digna R. Velez Edwards Devin Absher Noura S. Abul‐Husn Jorge Alsip Hana Bangash Mark Beasley Jennifer E. Below Eta S. Berner James Booth Wendy K. Chung James J. Cimino John J. Connolly Patrick Davis Beth Devine Stephanie M. Fullerton Candace Guiducci Melissa L. Habrat Heather S. Hain Hákon Hákonarson Margaret Harr Eden Haverfield Valentina Hernandez Christin Hoell Martha Horike‐Pyne George Hripcsak Marguerite R. Irvin Christopher Kachulis Dean Karavite Eimear E. Kenny Atlas Khan Krzysztof Kiryluk Bruce R. Korf Leah C. Kottyan Iftikhar J. Kullo Katie Larkin Cong Liu Edyta Małolepsza Teri A. Manolio Thomas May Elizabeth M. McNally Frank Mentch Alexandra Miller Sean D Mooney Priyanka Murali Brenda Mutai Naveen Muthu Bahram Namjou Emma Perez Megan J. Puckelwartz Tejinder Rakhra-Burris Dan M. Roden Elisabeth A. Rosenthal Seyedmohammad Saadatagah Maya Sabatello Dan Schaid Baergen I. Schultz Lynn Seabolt Gabriel Q. Shaibi Richard R. Sharp Mingjian Shi Johanna L. Smith Jordan W. Smoller Rene Sterling Sabrina A. Suckiel Jeritt G. Thayer Hemant K. Tiwari Susan Brown Trinidad Theresa L. Walunas

10.1016/j.gim.2023.100006 article EN cc-by-nc-nd Genetics in Medicine 2023-01-06

To improve human papillomavirus (HPV) vaccination rates, we studied the effectiveness of targeting automated decision support to families, clinicians, or both.Twenty-two primary care practices were cluster-randomized receive a 3-part clinician-focused intervention (education, electronic health record-based alerts, and audit feedback) none. Overall, 22, 486 girls aged 11 17 years due for HPV vaccine dose 1, 2, 3 randomly assigned within each practice family-focused with educational telephone...

10.1542/peds.2012-3122 article EN PEDIATRICS 2013-05-07

Electronic health record (EHR)-linked patient portals are a promising approach to facilitate shared decision-making between families of children with chronic conditions and pediatricians. This study evaluated the feasibility, acceptability, impact MyAsthma, an EHR-linked portal supporting for pediatric asthma.We conducted 6-month randomized controlled trial MyAsthma at 3 primary care practices. Families were which tracks families' asthma treatment concerns goals, children's symptoms,...

10.1542/peds.2014-3167 article EN PEDIATRICS 2015-03-10

Pediatric populations are uniquely vulnerable to the usability and safety challenges of electronic health records (EHRs), particularly those related medication, yet little is known about specific issues contributing hazards. To understand medication errors in care children, we analyzed 9,000 patient reports, made period 2012-17, from three different institutions that were likely EHR use. Of 3,243 (36 percent) had a issue contributed event, 609 (18.8 might have resulted harm. The general...

10.1377/hlthaff.2018.0699 article EN Health Affairs 2018-11-01

To assess the effects of electronic health record-based clinical decision support (CDS) and physician performance feedback on adherence to guidelines for acute otitis media (AOM) with effusion (OME).We conducted a factorial-design cluster randomized trial primary care practices (n = 24) as unit randomization visits analysis. Between December 2007 September 2010, data were collected from 139,305 made by 55,779 children aged 2 months 12 years. When activated, CDS system provided...

10.1542/peds.2012-1988 article EN PEDIATRICS 2013-03-12

The technical challenges in the development of a quality-controlled registry percutaneous coronary interventions (PCIs) are currently unknown. This article describes authors' experience regional, PCI registry. In 1996, 16 centers Michigan were invited to participate multicenter Nine agreed pilot data collection and, as July 2001, eight still actively collecting data. An Oracle database was developed by coordinating center. A common form and standard set definitions on during several...

10.1111/j.1540-8183.2002.tb01072.x article EN Journal of Interventional Cardiology 2002-10-01

Patient portals may improve communication between families of children with asthma and their primary care providers outcomes. However, the feasibility using to collect patient-reported outcomes from barriers facilitators portal implementation across diverse pediatric settings have not been established.We evaluated a patient for in care, its impact on management, success.We conducted mixed-methods study 20 practices (11 states). Using portal, parents aged 6-12 years completed monthly surveys...

10.2196/jmir.5610 article EN cc-by Journal of Medical Internet Research 2016-06-29

Objective Experiences sharing complex workflow-integrated clinical decision support (CDS) across health systems are sparse and not well reported. This case study presents the of a hybrid electronic record (EHR)-native SMART-compatible CDS tool for automating provision smoking cessation treatment caregivers during pediatric visits. Materials & Methods We conducted comprehensive needs assessment using socio-technical frameworks to identify workflow gaps technical requirements. A...

10.1055/a-2535-5823 article EN Applied Clinical Informatics 2025-02-11

Abstract Background Primary care pediatricians play an important role in genetic testing, including referrals, test ordering, responding to results, assessing risk, treatment, and managing care. As testing rapidly evolves include new tests identifying patients at risk for certain conditions, alert-based clinical decision support is insufficient assisting pediatric primary providers working with patients, parents, genetics, other specialties. Supporting the return of these results requires...

10.1055/a-2445-9185 article EN Applied Clinical Informatics 2025-01-01

Abstract Objective Sepsis recognition among infants in the Neonatal Intensive Care Unit (NICU) is challenging and delays can result devastating consequences. Although predictive models may improve sepsis outcomes, clinical adoption has been limited. Our focus was to align model behavior with clinician information needs by developing a machine learning (ML) pipeline two components: (1) predict baseline risk (2) detect evolving (dynamic) due physiologic changes. We then compared performance of...

10.1093/jamiaopen/ooaf015 article EN cc-by-nc JAMIA Open 2025-03-06

We describe the user-centered development of an electronic medical record–based portal, "MyAsthma," designed to facilitate shared decision making in pediatric asthma. Interviews and focus groups with 7 parents children asthma 51 clinical team members elicited 2 overarching requirements: that portal should support sustained communication ensure patient safety. Parents clinicians prioritized features including collecting parent child concerns goals; symptom, side effect, medication adherence...

10.1097/jac.0000000000000025 article EN Journal of Ambulatory Care Management 2014-03-03

Develop and evaluate an interactive information visualization embedded within the electronic health record (EHR) by following human-centered design (HCD) processes leveraging modern exchange standards.We applied HCD process to develop a Fast Healthcare Interoperability Resources (FHIR) application that displays patient's asthma history clinicians in pediatric emergency department. We performed preimplementation comparative system evaluation measure time on task, number of screens, retrieval...

10.1093/jamia/ocab016 article EN Journal of the American Medical Informatics Association 2021-01-21

Abstract Background Medical errors in blood product orders and administration are common, especially for pediatric patients. A failure modes effects analysis our health care system indicated high risk from the electronic ordering process. Objectives There two objectives of this study as follows: (1) To describe differences design original order sets (original design), new designed by expert committee (DEC), a third-version developed through user-centered (UCD). (2) compare number type...

10.1055/s-0039-3402714 article EN Applied Clinical Informatics 2019-10-01

To assess the current landscape of clinical decision support (CDS) tools in PICUs order to identify priority areas focus this field.International, quantitative, cross-sectional survey.Role-specific, web-based survey administered November and December 2020.Medical directors, bedside nurses, attending physicians, residents/advanced practice providers at Pediatric Acute Lung Injury Sepsis Network-affiliated PICUs.None.The was completed by 109 respondents from 45 institutions, primarily...

10.1097/pcc.0000000000002973 article EN Pediatric Critical Care Medicine 2022-04-28

Helping parents quit smoking is a public health priority. However, are rarely, if ever, offered tobacco use treatment through pediatric settings. Clinical decision support (CDS) systems developed for the workflows of primary care may consistent screening, treatment, and referral.This study aimed to develop CDS system by using human-centered design (HCD) that identifies who smoke, provides motivational messages (informed behavioral science), supports delivery evidence-based treatment.Our...

10.1055/s-0042-1748148 article EN Applied Clinical Informatics 2022-03-01
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