A5007026936- BRCA gene mutations in cancer
- Genomics and Rare Diseases
- Nutrition, Genetics, and Disease
- Ethics in Clinical Research
- Behavioral Health and Interventions
- CRISPR and Genetic Engineering
- Genetic Associations and Epidemiology
- Obesity and Health Practices
- Obesity, Physical Activity, Diet
- Ovarian cancer diagnosis and treatment
- Health Systems, Economic Evaluations, Quality of Life
- Cancer Genomics and Diagnostics
- Genetics, Bioinformatics, and Biomedical Research
- Climate Change Communication and Perception
- Eating Disorders and Behaviors
- Patient Dignity and Privacy
- Autism Spectrum Disorder Research
- Global Cancer Incidence and Screening
- Risk Perception and Management
- Health Promotion and Cardiovascular Prevention
- Smoking Behavior and Cessation
- Genetically Modified Organisms Research
- Media Influence and Health
- Prenatal Screening and Diagnostics
- Biomedical Ethics and Regulation
University College London
2008-2025
King's College London
2024-2025
PHG Foundation
2021-2025
Genomics (United Kingdom)
2025
Michigan State University
2024
Dominion University College
2024
Old Dominion University
2024
Great Ormond Street Hospital for Children NHS Foundation Trust
2018-2023
Icahn School of Medicine at Mount Sinai
2011-2022
Great Ormond Street Hospital
2016-2020
Prejudice against those who are perceived as 'fat' or obese (anti-fat prejudice) is rife, increasing, and associated with negative outcomes for targeted such treatment. The present review sought to identify describe published research on interventions reduce anti-fat prejudice. A systematic search of relevant databases (e.g. PsychInfo, PubMed, Scopus) found 16 studies that had Most notable was the lack reducing Methodological problems limit interpretability results were identified in...
Individual differences in several aspects of eating style have been implicated the development weight problems children and adults, but there are presently no reliable valid scales that assess a range dimensions style. This paper describes preliminary validation parent‐rated instrument to eight children; Children's Eating Behaviour Questionnaire (CEBQ). Constructs for inclusion were derived both from existing literature on behaviour interviews with parents. They included reponsiveness food,...
Abstract Objective: This study was designed to determine whether a community sample of obese mothers with young children used different feeding styles compared matched normal‐weight mothers. Four aspects style were assessed: emotional feeding, instrumental (using food as reward), prompting/encouragement eat, and control over eating. Research Methods Procedures: Participants from 214 families same‐sex twins; 100 in which both parents overweight or 114 normal weight lean. Results: We found...
In 2011, an Advanced Notice of Proposed Rulemaking proposed that de-identified human data and specimens be included in biobanks only if patients provide consent. The National Institutes Health Genomic Data Sharing policy went into effect 2015, requiring broad consent from almost all research participants.We conducted a systematic literature review attitudes toward biobanking, consent, sharing. Bibliographic databases MEDLINE, Web Science, EthxWeb, GenETHX. Study screening was using...
Background The risk of thromboembolic events in adults with primary immune thrombocytopenia has been little investigated despite findings increased susceptibility other thrombocytopenic autoimmune conditions. objective this study was to evaluate the among adult patients and without UK General Practice Research Database.Design Methods Using Database, 1,070 (≥18 years) coded records for first referenced between January 1st 1992 November 30th 2007, having at least one year pre-diagnosis three...
<h3>Background</h3> Self-Rated Health (SRH) as assessed by a single-item measure is an independent predictor of health outcomes. However, it remains uncertain which elements the subjective experience most strongly captures. In view its ability to predict outcomes, elucidation what determines SRH potentially important in provision services. This study aimed determine extent dimensions physical, mental and social functioning are associated with SRH. <h3>Methods</h3> We studied 20 853 men women...
Technological advances raise the possibility of systematic population-based genetic testing for cancer-predisposing mutations, but it is uncertain whether benefits outweigh disadvantages. We directly compared psychological/quality-of-life consequences such an approach to family history (FH)-based testing.In a randomized controlled trial BRCA1/2 gene-mutation in Ashkenazi Jewish (AJ) population, we all participants population screening (PS) arm with those fulfilling standard FH-based clinical...
Population-based testing for BRCA1/2 mutations detects the high proportion of carriers not identified by cancer family history (FH)-based testing. We compared cost-effectiveness population-based BRCA with standard FH-based approach in Ashkenazi Jewish (AJ) women.A decision-analytic model was developed to compare lifetime costs and effects amongst AJ women UK founder-mutation amongst: 1) all population age 30 years or older 2) just those a strong FH (≥10% mutation risk). The assumes that are...
Whole exome/genome sequencing (WES/WGS) is increasingly offered to ostensibly healthy individuals. Understanding the motivations and concerns of research participants seeking out personal WGS their preferences regarding return-of-results data sharing will help optimize protocols for WES/WGS. Baseline interviews including both qualitative quantitative components were conducted with (n=35) in HealthSeq project, a longitudinal cohort study individuals receiving results. Data recorded during...