A5036831373- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Cardiovascular Function and Risk Factors
- Coffee research and impacts
- Cardiovascular Syncope and Autonomic Disorders
- Acute Myocardial Infarction Research
- Alcohol Consumption and Health Effects
- Cardiac Imaging and Diagnostics
- Cardiovascular Disease and Adiposity
- Cardiac tumors and thrombi
- ECG Monitoring and Analysis
- Neurological disorders and treatments
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac Arrest and Resuscitation
- Mechanical Circulatory Support Devices
- Non-Invasive Vital Sign Monitoring
- Cardiac Structural Anomalies and Repair
- Cardiac Health and Mental Health
- Obstructive Sleep Apnea Research
- Venous Thromboembolism Diagnosis and Management
- Cardiovascular Effects of Exercise
- Heart Rate Variability and Autonomic Control
- Cardiovascular and Diving-Related Complications
The University of Melbourne
2011-2025
St Vincent's Hospital
2024-2025
The Alfred Hospital
2017-2024
Cabrini Hospital
2018-2024
Baker Heart and Diabetes Institute
2017-2024
Royal Australasian College of Physicians
2024
Monash University
2017-2024
Alfred Health
2018-2024
St Vincent's Health
2024
The Royal Melbourne Hospital
2017-2021
Excessive alcohol consumption is associated with incident atrial fibrillation and adverse remodeling; however, the effect of abstinence from on secondary prevention unclear.We conducted a multicenter, prospective, open-label, randomized, controlled trial at six hospitals in Australia. Adults who consumed 10 or more standard drinks (with 1 drink containing approximately 12 g pure alcohol) per week had paroxysmal persistent sinus rhythm baseline were randomly assigned 1:1 ratio to either...
Pulmonary vein isolation (PVI) alone is less effective in patients with persistent atrial fibrillation (AF) compared paroxysmal AF. The left posterior wall may contribute to maintenance of AF, and (PWI) a common PVI adjunct. However, PWI has not been subjected randomized comparison.
Lifestyle risk factors are a modifiable target in atrial fibrillation (AF) management. The relative contribution of individual lifestyle to AF development has not been described. Development and validation an score identify individuals at the general population aims study.The UK Biobank (UKB) Framingham Heart Study (FHS) large prospective cohorts with outcomes measured >10 years. Incident was based on International Classification Diseases version 10 coding. Prior excluded. Cox proportional...
Background: Population studies have demonstrated a range of sex differences including higher prevalence atrial fibrillation (AF) in men and risk AF recurrence women. However, the underlying reasons for this are unknown. This study evaluated whether sex-based electrophysiological substrate exist to account worse ablation outcomes Methods: High-density electroanatomic mapping left atrium was performed 116 consecutive patients with AF. Regional analysis across 6 segments. maps were created...
Abstract Aims Epidemiological studies report the beneficial effects of habitual coffee consumption on incident arrhythmia, cardiovascular disease (CVD), and mortality. However, impact different preparations outcomes survival is largely unknown. The aim this study was to evaluate associations between subtypes outcomes, utilizing UK Biobank. Methods results Coffee were defined as decaffeinated, ground, instant, then divided into 0, <1, 1, 2–3, 4–5, >5 cups/day, compared with...
Importance The impact of atrial fibrillation (AF) catheter ablation on mental health outcomes is not well understood. Objective To determine whether AF associated with greater improvements in markers psychological distress compared medical therapy alone. Design, Setting, and Participants Randomized Evaluation the Impact Catheter Ablation Psychological Distress Atrial Fibrillation (REMEDIAL) study was a randomized trial symptomatic participants conducted 2 centers Australia between June 2018...
Abstract Background and Aims Patterns of atrial fibrillation (AF) recurrence post-catheter ablation for persistent AF (PsAF) are not well described. This study aimed to describe the pattern seen following catheter PsAF implications healthcare utilization quality life (QoL). Methods was a post-hoc analysis CAPLA study, an international, multicentre that randomized patients with symptomatic pulmonary vein isolation plus posterior wall or alone. Patients underwent twice daily single lead ECG,...
Abstract Background and Aims Posterior wall isolation (PWI) is commonly incorporated into catheter ablation (CA) strategies for persistent atrial fibrillation (AF) in an attempt to improve outcomes. In the CAPLA randomized study, adjunctive PWI did not freedom from arrhythmia at 12 months compared with pulmonary vein (PVI) alone. Whether additional reduces recurrence over longer term remains unknown. Methods this multicenter, international, study patients AF undergoing index CA using...
Obesity is associated with higher electrical cardioversion (ECV) failure in persistent atrial fibrillation (PeAF). For ease-of-use, many centers prefer patches over paddles. We assessed the optimum modality and shock vector, as well safety efficacy of Manual Pressure Augmentation (MPA) technique.Patients obesity (BMI ≥ 30) PeAF undergoing ECV using a biphasic defibrillator were randomized into one four arms by (adhesive or handheld paddles) vector (anteroposterior [AP] anteroapical [AA]). If...
Abstract Aims Radiofrequency (RF) ablation for pulmonary vein isolation (PVI) in atrial fibrillation (AF) is associated with the risk of oesophageal thermal injury (ETI). Higher power short duration (HPSD) results preferential local resistive heating over distal conductive heating. Although HPSD has become increasingly common, no randomized study compared ETI conventional lower longer (LPLD) ablation. This aims to compare vs. LPLD on risk. Methods and Eighty-eight patients were 1:1 or...
Background Transesophageal echocardiography-guided direct cardioversion is recommended in patients who are inadequately anticoagulated due to perceived risk of left atrial appendage thrombus (LAAT); however, LAAT factors remain poorly defined. Methods and Results We evaluated clinical transthoracic echocardiographic parameters predict consecutive with fibrillation (AF)/atrial flutter undergoing transesophageal echocardiography before between 2002 2022. Regression analysis identified...