A5085597834- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Transplantation: Methods and Outcomes
- Renal Transplantation Outcomes and Treatments
- Cardiac pacing and defibrillation studies
- Cardiac Arrest and Resuscitation
- Viral Infections and Immunology Research
- Heart Failure Treatment and Management
- Diversity and Career in Medicine
- Cardiac Valve Diseases and Treatments
- Congenital Heart Disease Studies
- Organ Transplantation Techniques and Outcomes
- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Eosinophilic Disorders and Syndromes
- Cardiovascular Function and Risk Factors
- Pneumocystis jirovecii pneumonia detection and treatment
- Membrane-based Ion Separation Techniques
- Aortic Disease and Treatment Approaches
- Sex and Gender in Healthcare
- Respiratory Support and Mechanisms
- Fuel Cells and Related Materials
- Venous Thromboembolism Diagnosis and Management
- Infective Endocarditis Diagnosis and Management
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
The Alfred Hospital
2016-2025
Alfred Health
2012-2024
Baker Heart and Diabetes Institute
2009-2021
Monash University
2008-2021
Australian Centre for Heart Health
2021
University Hospitals of Cleveland
2018
Netherlands Heart Institute
2010
Office of the Director
2008
Australian Government
2008
National Health and Medical Research Council
2008
ulmonary hypertension affects ~50% of patients with advanced heart failure (AHF) and can be a barrier to cardiac transplantation.While inotropes are commonly used in low output, equipoise exists regarding the optimal agent, particularly context concomitant pulmonary hypertension. 1There remains conflicting data on hemodynamic effects milrinone versus dobutamine.As such, we investigated longer-term continuous intravenous compared dobutamine AHF awaiting transplantation.The for this study...
Cardiac resynchronization therapy (CRT) is advocated in advanced heart failure; however, patient selection remains challenging. We examined the utility of multi-sequential cardiac magnetic resonance imaging (CMR) predicting outcome after CRT. performed CMR on 40 subjects with cardiomyopathy and failure, despite optimized medical therapy. All patients had been recommended for CRT according to accepted clinical guidelines. Patients were defined by as likely responders if they significant...
Abstract Objectives Right ventricular failure following implantation of a durable left assist device (LVAD) is major driver mortality. Reported survival biventricular (BiVAD) or total artificial heart (TAH) remains substantially inferior to LVAD alone. We report our outcomes with and BiVAD HeartMate 3 (HM3). Methods Consecutive patients undergoing an HM3 between November 2014 December 2021, at The Alfred, Australia were included in the study. Comparison was made alone groups. Results A 86...
Improvements in cardiac transplant practice and immunosuppressive treatment have done much to curb the incidence of acute cellular rejection (ACR); however, antibody-mediated (AMR) allograft vasculopathy (CAV) remain prevalent. Recent studies shown that is governed by both allogeneic nonallogeneic factors such as inflammation. Initial suggested vascular endothelial growth factor (VEGF), a leukocyte mitogen produced activated cells leukocytes, may play specific role not only trafficking, but...
Background. Coronary allograft vasculopathy (CAV) remains a significant cause of morbidity and mortality after heart transplantation. The use aspirin for CAV prophylaxis has recently garnered interest as possible therapeutic adjunct in this setting. Methods. This 2-center retrospective cohort study included 372 patients who underwent transplantation between January 2009 March 2018 were stratified according to the commencement during their index transplant admission. primary outcome was...
Abstract Background Fulminant eosinophilic myocarditis (EM) is a rare and often fatal condition that may present atypically be complicated by ventricular arrhythmias. Treatment involves high-dose corticosteroids to suppress eosinophilia, as well increasing use of mepolizumab, an anti-interleukin-5 antibody with evidence for long-term efficacy safety. Case summary A 38-year-old woman presented the emergency department neck pain fatigue, after extensive investigation was diagnosed EM secondary...
Significant gender disparities exist in some medical specialties, particularly cardiology. We assessed work, personal life and work-life balance women cardiology Australia New Zealand (NZ), compared with other to determine factors that may contribute the lack of specialty.
To describe the use of levosimendan in a quaternary referral center with dedicated heart failure service and compare its efficacy safety to continuous outpatient support inotropes (COSI) among patients advanced (AHF) who require bridge-to-decision (BTD) or bridge-to-transplant (BTT) therapy. This study was retrospective, single-center, descriptive AHF received either single infusion COSI between 2018 2021. A total 23 infusion, 14 were started on COSI. Three indications for identified: (1)...
Juvenile hemochromatosis is the most severe form of iron overloading phenotype. Although rare, it should be suspected in patients who present with hypogonadotropic hypogonadism, diabetes mellitus, or cardiomyopathy without a clear cause.A young Serbian male presenting end-stage heart failure was referred for extracorporeal membrane oxygenation. An endomyocardial biopsy revealed cytoplasmic deposits myocytes. His condition stabilized biventricular assist devices and he listed transplantation....