A5070774369- Photoacoustic and Ultrasonic Imaging
- Breast Lesions and Carcinomas
- Optical Imaging and Spectroscopy Techniques
- Breast Cancer Treatment Studies
- Advanced MRI Techniques and Applications
- MRI in cancer diagnosis
- Radiomics and Machine Learning in Medical Imaging
- Ultrasound Imaging and Elastography
- Optical Coherence Tomography Applications
- Global Cancer Incidence and Screening
- Radiopharmaceutical Chemistry and Applications
- BRCA gene mutations in cancer
- AI in cancer detection
- Breast Implant and Reconstruction
- Medical Imaging Techniques and Applications
- Colorectal Cancer Screening and Detection
- Anorectal Disease Treatments and Outcomes
- Cancer survivorship and care
- Photodynamic Therapy Research Studies
- Dysphagia Assessment and Management
- Radiation Dose and Imaging
- Nanoparticle-Based Drug Delivery
- Advanced Radiotherapy Techniques
- Salivary Gland Tumors Diagnosis and Treatment
- Patient-Provider Communication in Healthcare
The University of Texas Health Science Center at San Antonio
2009-2024
The University of Texas Health Science Center at Houston
2007-2022
The University of Texas at San Antonio
2011
Audie L. Murphy Memorial VA Hospital
2004
The University of Texas System
1998
Medizinische Hochschule Hannover
1974-1994
University of Florida
1990-1992
Columbia College - Missouri
1985
Background Gadopiclenol is a macrocyclic gadolinium-based contrast agent (GBCA) with higher relaxivity compared standard GBCAs, potentially allowing gadolinium dose reduction without decreasing efficacy. Purpose To investigate whether gadopiclenol at 0.05 mmol/kg noninferior to gadobutrol 0.1 for lesion visualization in body MRI. Materials and Methods A randomized, double-blind, crossover, phase 3 study was conducted between August 2019 December 2020 33 centers 11 countries. Adults least one...
Background Optoacoustic imaging can assess tumor hypoxia coregistered with US gray-scale images. The combination of optoacoustic and may have a role in distinguishing breast cancer molecular subtypes. Purpose To investigate whether feature scores correlate Materials Methods A total 1972 women (with 2055 masses) underwent prebiopsy prospective multi-institutional study between December 2012 September 2015. Seven readers blinded to pathologic diagnosis scored features the known cancers. within...
Abstract Context.—Management of breast needle core biopsies diagnosed as atypical ductal hyperplasia, lobular and carcinoma in situ is controversial. Current recommendations involve excisional biopsy to rule out and/or invasive carcinoma, which have been reported more than 50% cases some series. Objective.—To determine how frequently these diagnoses made on are ultimately found represent or based specimens, order identify predictive factors. Design.—One thousand eight hundred thirty-six...
Context.-Management of breast needle core biopsies diagnosed as atypical ductal hyperplasia, lobular and carcinoma in situ is controversial. Current recommendations involve excisional biopsy to rule out and/or invasive carcinoma, which have been reported more than 50% cases some series. Objective.-To determine how frequently these diagnoses made on are ultimately found represent or based specimens, order identify predictive factors. Design.-One thousand eight hundred thirty-six image-guided...
We describe two laser optoacoustic imaging systems for breast cancer detection based on arrays of acoustic detectors operated manually in a way similar to standard ultrasonic imaging. The have the advantages light illumination (regardless interrogated part breast), ability visualize any breast, and convenience operation. first system could work both mode, was developed linear probe with parallel rectangular optical bundles. used it pilot clinical study provide time demonstration that...
A study was designed to determine whether plain films, used as a screening modality for magnetic resonance imaging (MRI), could reliably detect intraorbital metallic foreign objects.In the first experiment, 20 metal particles were placed in five human cadaver orbits. Routine orbital film series and computed tomography (CT) obtained, randomized, interpreted blinded by three experienced radiologists.The threshold size of particle detection CT (0.07 mm3) lower than films (0.12 mm3). Placing...
We report on findings from the clinical feasibility study of Imagio<sup>TM</sup>. Breast Imaging System, which acquires two-dimensional opto-acoustic (OA) images co-registered with conventional ultrasound using a specialized duplex hand-held probe. Dual-wavelength technology is used to generate parametric maps based upon total hemoglobin and its oxygen saturation in breast tissues. This may provide functional diagnostic information pertaining tumor metabolism microvasculature, complementary...
Racial and ethnic disparities have included a lack of access to both genetic testing research, resulting in poor understanding the genomic architecture under-represented populations. The South Texas population is primarily Hispanic background has been largely devoid services. We extended this underserved uncovered variants previously not observed, emphasizing need continually improve databases clarification variant significance provide meaningful patient counseling.
We have designed, fabricated and tested a new laser optoacoustic imaging system (LOIS-64/16) for quantitative tomography of breast cancer. The was designed to create single slice an image the with 64 ultrawide band acoustic transducers. Other 16 transducers on back probe were used reconstruct light distribution inside breast. resolution at least 0.5 mm high-aspect-ratio objects. Maximum sensitivity 4.8 mV/Pa RMS noise 3.1 mV, which allowed small (less than 1 cm) tumors depths over 3 cm....
Functional opto-acoustic (OA) imaging was fused with gray-scale ultrasound acquired using a specialized duplex handheld probe. Feasibility Study findings indicated the potential to more accurately characterize breast masses for cancer than conventional diagnostic (CDU). The included OA imagery of 74 that were collected investigational Imagio® system. Superior specificity and equal sensitivity CDU demonstrated, suggesting fusion may potentially obviate need negative biopsies without missing...
We present results from a clinical case study on imaging breast cancer using real-time interleaved two laser optoacoustic system co-registered with ultrasound. The version of Laser Optoacoustic Ultrasonic Imaging System (LOUIS) utilizes commercial linear ultrasonic transducer array, which has been modified to include parallel rectangular optical bundles, operate in both (US) and (OA) modes. In OA mode, the images wavelengths (755 nm 1064 nm) that provide opposite contrasts for absorption...
Two-dimensional optoacoustic imaging with a hand-held probe operated in backward mode is being developed for diagnostic of breast cancer to evaluate the feasibility dual-modality plus ultrasonic system that maps functional information anatomical tissue structures resolution. Tissue illuminated at 757nm and 1064nm optical contrast between hypoxic blood carcinomas normally oxygenated benign masses. The optimized calibrated phantoms pilot clinical study patients masses suspected malignancy....
Objective: The aim of this study was to evaluate the relationship satisfaction with cancer care doctor and health-related quality life (HRQOL) among Latina breast survivors (BCS) by (1) assessing whether would be positively correlated HRQOL (2) significantly influence while controlling for covariates. Methods: cross-sectional used self-report data from 117 BCS. Satisfaction measured Hall Index, Functional Assessment Cancer Therapy–General (FACT-G). Analyses included calculation descriptive...
To evaluate the performance of a biopsy decision support algorithmic model, intelligent-augmented breast cancer risk calculator (iBRISK), on multicenter patient dataset.
We present results from a recent study involving the Imagio<sup>TM</sup> breast imaging system, which produces fused real-time two-dimensional color-coded opto-acoustic (OA) images that are co-registered and temporally inter- leaved with gray scale ultrasound using specialized duplex handheld probe. The use of dual optical wavelengths provides functional blood map tissue tumors displayed high contrast based on total hemoglobin oxygen saturation blood. This diagnostic information pertaining...
Post-operative radiotherapy has commonly been used for early stage breast cancer to treat residual disease. The primary objective of this work was characterize, through dosimetric and radiobiological modeling, a novel focal brachytherapy technique which uses direct intracavitary infusion β-emitting radionuclides (186Re/188Re) carried by lipid nanoparticles (liposomes). Absorbed dose calculations were performed spherical lumpectomy cavity with uniformly injected activity distribution using...