A5011129307- Sirtuins and Resveratrol in Medicine
- Cryptography and Data Security
- Blockchain Technology Applications and Security
- MicroRNA in disease regulation
- Adipose Tissue and Metabolism
- Autophagy in Disease and Therapy
- Pancreatic function and diabetes
- Metabolism, Diabetes, and Cancer
- Cloud Data Security Solutions
- Diet, Metabolism, and Disease
- Renal and related cancers
- Adenosine and Purinergic Signaling
- Plant-derived Lignans Synthesis and Bioactivity
- Epigenetics and DNA Methylation
- Endoplasmic Reticulum Stress and Disease
- Estrogen and related hormone effects
- Biochemical effects in animals
- Diet and metabolism studies
- Olfactory and Sensory Function Studies
- Iron Metabolism and Disorders
- Privacy-Preserving Technologies in Data
- Advanced Chemical Sensor Technologies
- Birth, Development, and Health
- FOXO transcription factor regulation
- Genomics, phytochemicals, and oxidative stress
China Medical University
2014-2024
Fourth Affiliated Hospital of China Medical University
2019-2024
First Hospital of China Medical University
2019
This study examines gender differences in associations of serum ferritin and diabetes, metabolic syndrome (MetS), obesity Chinese.Based on a nationwide, population-based China Health Nutrition survey this included 8564 men women aged 18 years or older. Anthropometric fasting blood glucose, insulin, lipids, ferritin, transferrin data were collected. Ferritin concentrations higher than (201.55 ± 3.6 versus 80.46 1.64 ng/mL, p < 0.0001). The prevalences MetS, obesity, overweight 8.05, 8.97,...
Aims: To explore the molecular mechanism by which 17β-estradiol (estrogen 2, E2) regulates glucose transporter 2 (GLUT2) and insulin secretion in islet β cells through G protein-coupled estrogen receptor (GPER) via Akt/mTOR pathway. Methods: SPF-grade SD male rats were used to establish an vivo type diabetes model treated with E2. Rat insulinoma (INS-1) cultured normal or high media without Immunofluorescence double staining was detect GPER, GLUT2, insulin, glucagon immunolocalization rat...
The study is aimed at verifying miR-154-5p and Smurf1 combination in glomerular mesangial cells regulating TGFβ1/Smad3 pathway-related protein ubiquitination the model of diabetic rats renal tissues, primary cells, cell lines.The SD rat high-glucose-cultured lines were established. mimic inhibitor, siRNA, TGF β 1/Smad3 inhibitor (SB431542) pretreated to make pathway ubiquitin changes. Fluorescence situ hybridization was used for localization; molecular biological detection adopted...
Thyroid carcinoma (TC) is one of the frequent endocrine malignancies, and growing evidence suggests that aberrant microRNA (miRNA) expression contributes to TC development progression. Nevertheless, function miR-330-5p in progression remains unknown. The levels miR-330-5 patients with thyroid healthy controls were detected, their potential diagnostic prognostic values analyzed. In this study, we firstly found was markedly upregulated tissue cell lines. Functionally, downregulation suppressed...
Arctium lappa has a long medicinal and edible history with great economic importance. We combined Illumina PacBio sequences to generate the first high-quality chromosome-level draft genome of A. lappa. The assembled is approximately 1.79 Gb N50 contig size 6.88 Mb. Approximately 1.70 (95.4%) were anchored onto 18 chromosomes using Hi-C data; scaffold was improved be 91.64 Furthermore, we obtained 1.12 (68.46%) repetitive 32,771 protein-coding genes; 616 positively selected candidate genes...
With the extensive application of blockchain technology, there is an increasing demand for querying data. Verifiable query processing (VQPBC) assures integrity without need to store entire database. To best our knowledge, prior work Vchain+ serves as state art in VQPBC. However, it still suffers from following limitations: (i) fewer SQL-like queries; (ii) low efficiency; and (iii) impractical public key management. this end, we propose a novel solution, which additionally supports aggregate...