A5102913165- Orbital Angular Momentum in Optics
- Cancer, Hypoxia, and Metabolism
- Cancer-related Molecular Pathways
- Autophagy in Disease and Therapy
- Chronic Myeloid Leukemia Treatments
- Microfluidic and Bio-sensing Technologies
- Plasmonic and Surface Plasmon Research
- Eosinophilic Disorders and Syndromes
- Glutathione Transferases and Polymorphisms
- Quantum Dots Synthesis And Properties
- RNA modifications and cancer
- Chronic Lymphocytic Leukemia Research
- Anodic Oxide Films and Nanostructures
- Silicon Nanostructures and Photoluminescence
- Click Chemistry and Applications
- Cold Atom Physics and Bose-Einstein Condensates
- Nanoparticle-Based Drug Delivery
- Viral Infectious Diseases and Gene Expression in Insects
- Nanowire Synthesis and Applications
- Digital Holography and Microscopy
- Semiconductor Quantum Structures and Devices
- Mechanical and Optical Resonators
- Dendrimers and Hyperbranched Polymers
- Liver Disease Diagnosis and Treatment
- Copper-based nanomaterials and applications
Guiyang Medical University
2023-2024
Affiliated Hospital of Guizhou Medical University
2023-2024
Tongji University
2023-2024
National Institute of Metrology
2023-2024
Biopharma Technology (United Kingdom)
2017
BioPharm (United Kingdom)
2017
University at Buffalo, State University of New York
2016
Chongqing Medical University
2011
Abstract Bone marrow mesenchymal stem cell (BMSC) transplantation is a promising regenerative therapy; however, the survival rate of BMSCs after low. Oxidative stress one main reasons for high apoptosis transplantation, so there an urgent need to explore mechanism oxidative stress-induced BMSCs. Our previous transcriptome sequencing results suggested that expression P53-induced nuclear protein 1 (TP53INP1) and tumor suppressor P53 (P53) was significantly upregulated during process The...
Optical meron is a type of nonplanar topological texture mainly observed in surface plasmon polaritons and highly symmetric points photonic crystals the reciprocal space. Here, we report Poynting-vector merons formed at real space crystal for Γ-point illumination. can be utilized subwavelength-resolution manipulation nanoparticles, resembling Hall effect on electrons via magnetic merons. In particular, staggered antimerons impose strong radiation pressure large gold nanoparticles (AuNPs),...
Hypoxia-induced apoptosis of bone marrow mesenchymal stem cells (BMSCs) limits the efficacy their transplantation for steroid-induced osteonecrosis femoral head (SONFH). As and RNA methylation are closely related, exploring role mechanism in hypoxic BMSCs is expected to identify new targets SONFH enhance efficacy. We performed methylated immunoprecipitation sequencing (MeRIP-seq) combined with RNA-seq on a hypoxia-induced BMSC model found that methyltransferase-like 3 (METTL3) involved...
Sorting nanoparticles is of paramount importance in numerous physical, chemical, and biomedical applications. Current technologies for sorting dielectric have a common size limit resolution approximately 20 10 nm, respectively. It remains grand challenge to push the limit. Herein, new physics that deploys toroidal multipole responses metasurface exert strong distinguishable optical forces on sub‐10 nm unravelled. The electric dipole, quadrupole emerge with distinct light force patterns,...
Optofluidic Sorting In article number 2300100, Xiang Fang, Yuzhi Shi, Xinbin Cheng, and co-workers achieve 1 nm-precision sorting of sub-10 nm polystyrene nanoparticles 3 exsomes by exploiting the electromagnetic toroidal dipole multipoles in a dielectric metasurface. Medium-sized can be screened out from mixture different gold sorted with photonic slot.
Kinase inhibitors that target Bcr-Abl are highly effective in the treatment of chronic myeloid leukemia (CML).However, these often invalidated due to drug resistance.Therefore, discovery and development novel is required overwhelm resistance CML resistant currently used first-line inhibitors.Herein we have described a newly developed inhibitor CT-721, which displayed potent inhibitory effects on wild-type T315I mutant Bcr-Abl.It functioned as typically ATP-competitive inhibitor, superior...
To achieve higher therapeutic efficiency with catabatic side effects, desirable nanocarriers should be designed to retain the loaded drug tightly during systemic circulation, but release rapidly and efficiently upon endocytosis by tumor cells. Herein, we synthesized a novel folate conjugated poly(ethylene glycol)-poly(L-glutamic acid)-poly(L-phenylalanine) (folate-PEG-PLG(HS)-PPhe) copolymer desired controlled delivery of doxorubicin (DOX). The could self-assemble into interlayer-crosslinked...
Abstract Bone marrow mesenchymal stem cell (BMSC) transplantation is a promising regenerative therapy, but the survival rate of BMSCs after low. Oxidative stress one main reasons for high apoptosis transplantation, so there an urgent need to explore mechanism oxidative stress-induced BMSCs. Our previous transcriptome sequencing results suggested that expression P53-induced nuclear protein 1 (TP53INP1) and tumor suppressor P53 (P53) was significantly upregulated during process The present...
Harnessing exotic optical forces promises a plethora of biophysical applications and novel light-matter interactions. The pulling force (OPF) lateral (OLF) have been studied separately, yet synthesizing both candidates simultaneously remains an unsolved challenge could offer more powerful manoeuvre particles. Here, we report coordinated scheme to harness these two together present dynamically controlled two-dimensional (2D) microvehicle. strategy is leverage unexplored helicity-dependent...
GaAs nanostructures were grown on patterned (111) B substrates with molecular beam epitaxy. Nanopatterns achieved by patterning a thin film of silicon dioxide (SiO2) the substrate surface self-organized porous alumina template. Growth took place through holes in SiO2 film. The authors obtained two kinds nanostructures: nanopillars and nanodots. majority had tops, i.e., hexagonal flat top pyramidal top, as observed scanning electron microscope. High resolution transmission microscopy studies...