A5041517424- Memory and Neural Mechanisms
- Neuroscience and Neuropharmacology Research
- Neural dynamics and brain function
- Neurogenesis and neuroplasticity mechanisms
- Photoreceptor and optogenetics research
- MicroRNA in disease regulation
- Zebrafish Biomedical Research Applications
- Neuroinflammation and Neurodegeneration Mechanisms
- Olfactory and Sensory Function Studies
- Nerve injury and regeneration
- Adipose Tissue and Metabolism
- Receptor Mechanisms and Signaling
- Concrete Corrosion and Durability
- Ion channel regulation and function
- Sleep and Wakefulness Research
- Neurobiology and Insect Physiology Research
- Functional Brain Connectivity Studies
- Dam Engineering and Safety
- Congenital heart defects research
- Geological formations and processes
- Visual perception and processing mechanisms
- Soil and Unsaturated Flow
Centre Neurosciences intégratives et Cognition
2023-2024
Institut de Neurosciences Cognitives et Intégratives d’Aquitaine
2024
Université Paris Cité
2017-2023
Centre National de la Recherche Scientifique
2017-2023
Centre Interdisciplinaire de Recherche en Biologie
2018-2023
Inserm
2015-2021
Collège de France
2018-2021
Université Paris Sciences et Lettres
2021
Sorbonne Université
2017-2018
Institut du Cerveau
2017-2018
Abstract Orientation in space is represented specialized brain circuits. Persistent head direction signals are transmitted from anterior thalamus to the presubiculum, but identity of presubicular target neurons, their connectivity and function local microcircuits unknown. Here, we examine how thalamic afferents recruit principal neurons Martinotti interneurons, ensuing synaptic interactions between these cells. Pyramidal neuron activation cells superficial layers strongly facilitating such...
Article18 October 2021Open Access Transparent process Npas4 regulates medium spiny neuron physiology and gates cocaine-induced hyperlocomotion Thomas Lissek Corresponding Author [email protected] orcid.org/0000-0003-4748-5474 Interdisciplinary Center for Neurosciences, Department of Neurobiology, Heidelberg University, Heidelberg, Germany Search more papers by this author Andry Andrianarivelo orcid.org/0000-0002-6369-4201 INSERM, UMR-S 1130, Neuroscience Paris Seine, Institute Biology Paris,...
The presubiculum contains head direction cells that are crucial for spatial orientation. Here, we examined the connectivity and strengths of thalamic inputs to presubicular layer 3 neurons projecting medial entorhinal cortex in mouse. We recorded pairs projection interneurons while optogenetically stimulating afferent fibers from anterior nuclei. Thalamic input differentially affects neurons: pyramidal fast-spiking parvalbumin-expressing directly monosynaptically activated, with depressing...
The presubiculum (PrS) is part of an interconnected network distributed brain regions where individual neurons signal the animals heading direction. PrS sends axons to medial entorhinal cortex (MEC), it reciprocally connected with anterior thalamic nuclei (ATNs), and feedback projections lateral mammillary nucleus (LMN), involved in generating head direction signal. intrinsic properties projecting will influence pathway-specific transmission activity. Here, we used projection-specific...
Summary Head-direction (HD) signals function as the brain’s internal compass. They are organized an attractor, and anchor to environment via visual landmarks. Here we examine how thalamic HD landmark information from retrosplenial cortex combine in presubiculum. We find that monosynaptic excitatory connections anterior nucleus converge on single layer 3 pyramidal neurons dorsal portion of mouse Independent dual wavelength photostimulation these inputs slices leads action potential generation...
Head-direction (HD) signals function as the brain’s internal compass. They are organized an attractor, and anchor to environment via visual landmarks. Here we examine how thalamic HD landmark information from retrosplenial cortex combine in presubiculum. We find that monosynaptic excitatory connections anterior nucleus converge on single layer 3 pyramidal neurons dorsal portion of mouse Independent dual wavelength photostimulation these inputs slices leads action potential generation...
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ABSTRACT The presubiculum contains head direction cells that are crucial for spatial navigation. Here, we examined the connectivity and strengths of thalamic inputs to presubicular layer 3 neurons projecting medial entorhinal cortex in mouse. We recorded pairs projection interneurons while optogenetically stimulating afferent fibers from anterior nuclei (ATN). Thalamic input differentially affects neurons: pyramidal fast-spiking parvalbumin expressing (PV) directly monosynaptically...
Oligodendrocytes form myelin for central nervous system axons and release factors which signal to neurons during myelination. Here, we ask how oligodendroglial influence hippocampal GABAergic neuron physiology. In mixed cultures, fired action potentials (APs) of short duration received high frequencies excitatory synaptic events. purified neuronal cultures without glial cells, excitability increased the frequency events decreased. These effects were largely reversed by adding oligodendrocyte...
ABSTRACT Orientation in space is represented specialized brain circuits. Persistent head direction signals are transmitted from anterior thalamus to the presubiculum, but identity of presubicular target neurons, their connectivity and function local microcircuits unknown. Here we examine how thalamic afferents recruit principal neurons Martinotti interneurons ensuing synaptic interactions between these cells. Pyramidal neuron activation cells superficial layers strongly facilitating such...
ABSTRACT Oligodendrocytes form myelin for central nervous system axons and release factors which signal to neurons during myelination. Here, we ask how oligodendroglial influence hippocampal GABAergic neuron physiology. In mixed cultures fired action potentials of short duration received high frequencies excitatory synaptic events. purified neuronal without glial cells, excitability increased the frequency events decreased. These effects were largely reversed by adding oligodendrocyte...
Head-direction (HD) signals function as the brain’s internal compass. They are organized an attractor, and anchor to environment via visual landmarks. Here we examine how thalamic HD landmark information from retrosplenial cortex combine in presubiculum. We find that monosynaptic excitatory connections anterior nucleus converge on single layer 3 pyramidal neurons dorsal portion of mouse Independent dual wavelength photostimulation these inputs slices leads action potential generation...
Les géosynthétiques bentonitiques (GSB) sont souvent utilisés pour la réalisation de barrières étanches. Afin mesurer les débits traversant un GSB et, en particulier, dans zones recouvrement, nouvel appareillage a été développé au laboratoire URGC-Géotechnique l’INSA Lyon. Après avoir présenté résultats d’un essai recouvrement réalisé avec différentes conditions confinement et charge hydraulique, nous montrons l’intérêt simulation numérique compréhension tel écoulement, détermination...